导师风采
代华平

个人信息

Personal Information

  • 性别:女
  • 导师类型:博士生导师
  • 职称:教授
  • 该职称任职时间:20150730

联系方式

Contact Information

  • 所属院系:中日友好医院
  • 所属专业:内科学
  • 邮箱 : daihuaping@ccmu.edu.cn
  • 工作电话 : 84206271

个人简介

Personal Profile

代华平,女,主任医师,教授。现任中日医院呼吸中心副主任,内科教研室主任,中国医学科学院北京协和医学院博士研究生导师,首都医科大学博士研究生导师,中华医学会呼吸病学分会常务委员兼副秘书长,中华医学会呼吸病学分会间质性肺疾病学组组长,中国医师协会呼吸医师分会常务委员兼总干事,《国际呼吸杂志》、《中国临床医生杂志》副主编,《Chin Med J》、《Cur Med Sci》、《中华结核与呼吸杂志》编委。长期从事呼吸系统疾病医、教、研工作,积累了丰富经验,擅长间质性肺疾病与呼吸疑难杂症的诊治。1980-1985毕业于武汉同济医科大学,获医学临床学士学位;1985-1988毕业于武汉同济医科大学,获医学硕士学位;1996-1999毕业于德国Essen大学医学院,获医学博士学位。1988.07-2015.06:北京朝阳医院住院、主治、副主任、主任医师2004.07-2005.01:美国圣路易斯华盛顿大学医学院访问学者2015.08-至今:中日友好医院呼吸与危重症医学科主任医师论文成果:以第一或责任作者在Eur Respir J、Chest、Cell Research、中华医学杂志等国内外著名学术刊物发表论文100余篇,主编/主译、副主编专著/教材20部,参编全国高等医学教材《内科学》第8版、第9版。

团队简介

Team Profile

待补充更新

  • 研究方向Research Directions
内科学(呼吸系病)
  • 在校研究生Current Graduate Students

硕士研究生 0 名,博士研究生 5 名

  • 科研项目Research Projects
# 项目名称 起止日期 金额 项目类型 本人角色
1中国特发性肺(间质)纤维化疾病注册登记研究 Idiopathic Pulmonary Fibrosis Registry China Study (PORTRAY)2017-07-01 —— 2025-12960万元主持在研的国家或省部级科研项目主持者
2基于全国性百万自然人群队列和生物银行的资 源共享平台建设和多病防控应用研究2021-09-30 —— 2025-12-31480.0主持在研的国家或省部级科研项目参与者
3纤维化间质性肺疾病的早期识别与治疗策略2021-12-20 —— 2024-11-012600.0主持在研的国家或省部级科研项目主持者
4衰老相关通路TSP-1-YAP调控肺泡再生与肺纤维化2024-01 —— 2027-1248万元参与在研的国家或省部级科研项目主持人
5纤维化间质性肺疾病的综合管理体系构建研究2024-01 —— 2026-12130万元参与在研的国家或省部级科研项目主持人
6PCCM专培结业学员职业发展跟踪调查(2022-HX-106-jz)2022-10 —— 2025-0687.46万元参与在研的国家或省部级科研项目主持人
  • 发表论文Papers
# 论文题目 期刊名称 发表年份 论文署名
1胰岛素样生长因子Ⅰ/细胞外信号调节激酶通路在肺纤维化中的作用及可能机制中华医学杂志2022-06-12代华平
2原发性干燥综合征合并间质性肺疾病的生物标志物进展国际呼吸杂志2022-06-12代华平
3Rapamycin increases CCN2 expression of lung fibroblasts via phosphoinositide 3-kinase.Lab Invest.2022-06-12代华平
4Fatty Acid Metabolism and Idiopathic Pulmonary FibrosisFront Physiol. 2022,12:7946292022-06-12代华平
5中国肺结节病诊断和治疗专家共识中华结核和呼吸杂志2022-06-12代华平
6抗合成酶综合征合并间质性肺疾病患者的临床特征中华医学杂志2022-06-12代华平
7The Role of Diverse Immune Cells in SarcoidosisFRONTIERS IN IMMUNOLOGY,2021,12.2022-06-12代华平
8Therapeutic Applications of Mesenchymal Stem Cells in Idiopathic Pulmonary FibrosisFRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY,2021,9.2022-06-12代华平
9Paracrine factors from mesenchymal stem cells attenuate epithelial injury and lung fibrosisMol Med Rep.2022-06-12代华平
10Down-regulation of USP13 mediates phenotype transformation of fibroblasts in idiopathic pulmonary fibrosis.Respir Res.2022-06-12代华平
11终末期结节病患者肺移植时机及预后中华结核和呼吸杂志2022-06-12代华平
12The effect of 1.9-mm versus 2.4-mm probes in transbronchial cryobiopsies for interstitial lung diseases: a prospective analysisANNALS OF TRANSLATIONAL MEDICINE,2021,9(1).2022-06-12代华平
13嗜酸性肉芽肿性血管炎43例临床分析中华医学杂志2022-06-12代华平
14Incidence and Clinical Characteristics of Pulmonary Hypertension in Patients with Idiopathic Pulmonary FibrosisChin Med J (Engl). 2022-06-12代华平
15"Using contrast-enhanced CT and non-contrast-enhanced CT to predict EGFR mutation status in NSCLC patients-a radiomics nomogram analysis"Eur Radiol. 2022,32(4):2693-2703.2022-06-12代华平
16Graft dysfunction and rejection of lung transplant, a review on diagnosis and managementClin Respir J. 2022,16(1):5-12. 2022-06-12代华平
17The autocrine CXCR4/CXCL12 axis contributes to lung fibrosis through modulation of lung fibroblast activityExp Ther Med.?2020 Mar;19(3):1844-1854.2022-06-12代华平
18Krebs von den Lungen-6 levels in untreated idiopathic pulmonary fibrosis"Clin Respir J . 2022,16(3):234-243."2022-06-12代华平
19Pirfenidone ameliorates silica-induced lung inflammation and fibrosis in mice by inhibiting the secretion of interleukin-17AActa Pharmacol Sin. 2022,43(4):908-918. 2022-06-12代华平
20Current therapies for patients with acute exacerbation of idiopathic pulmonary fibrosisChin Med J (Engl). 2020 Jun 20;133(12):1470-1472.2022-06-12代华平
21Serum Krebs von den Lungen-6 level as a diagnostic biomarker for interstitial lung disease in Chinese patients.Clin Respir J.2022-06-12代华平
22Drug-induced pulmonary toxicity in breast cancer patients treated with systemic therapy: a systematic literature reviewEXPERT REVIEW OF ANTICANCER THERAPY,2021,21(12):1399-1410.2022-06-12代华平
23Global and regional burden of interstitial lung disease and pulmonary sarcoidosis from 1990 to 2019: results from the Global Burden of Disease study 2019Thorax. 2021;thoraxjnl-2020-216732.2022-06-12代华平
24结节病的免疫学研究进展中华结核和呼吸杂志2022-06-12代华平
25与基因和家族遗传相关的间质性肺疾病中华医学杂志2022-06-12代华平
26特发性肺纤维化:咳嗽及其处理中华结核和呼吸杂志2022-06-12代华平
27特发性肺纤维化注册登记研究介绍中华结核和呼吸杂志2022-06-12代华平
28特发性肺纤维化急性加重研究进展华西医学2022-06-12代华平
29Spectrum of interstitial lung disease in China from 2000 to 2012.Eur Respir J. 2018 Sep 6;52(3)2022-06-12代华平
30miR-130b-3p Modulates Epithelial-Mesenchymal Crosstalk in Lung Fibrosis by Targeting IGF-1Plos One. 2022-06-12代华平
31[THE CLINICAL FEATURES OF PRIMARY OR METASTATIC MALIGNANCIES PRESENTING WITH MULTIPLE LUNG CAVITIES].中华结核和呼吸杂志2022-06-12代华平
32Safety and diagnostic efficacy of cone beam computed tomography-guided transbronchial cryobiopsy for interstitial lung disease: a cohort studyEur Respir J. 2020 Mar 26;20007242022-06-12代华平
33Coronavirus disease 2019-associated pulmonary fibrosis: clinical findings, pathogenesis, and potential treatmentCHINESE MEDICAL JOURNAL,2021,134(15):1792-17942022-06-12代华平
34Dihydromyricetin Alleviates Pulmonary Fibrosis by Regulating Abnormal Fibroblasts Through the STAT3/p-STAT3/GLUT1 Signaling Pathway"Front Pharmacol . 2022 Mar 14;13:834604."2022-06-12代华平
35日本2018年特发性肺纤维化治疗指南介绍中华结核和呼吸杂志2022-06-12代华平
36第482例 慢性乙型肝炎—肾病综合征—右肺空洞—左肺实变中华医学杂志2022-06-12代华平
37外泌体在肺部疾病中的研究进展中华结核和呼吸杂志2022-06-12代华平
38Toll-like receptor 4 promotes fibrosis in bleomycin-induced lung injury in miceGenet Mol Res.2022-06-12代华平
39Recurrent bilateral spontaneous pneumothorax secondary to lung adenocarcinoma with epidermal growth factor receptor mutation. Thorac Cancer.2022-06-12代华平
40Pulmonary fibrosis in a mouse model of sarcoid granulomatosis induced by booster challenge with Propionibacterium acnes.Oncotarget.2022-06-12代华平
41Modeling alveolar injury using microfluidic co-cultures for monitoring bleomycin-induced epithelial/fibroblastic crosstalk disorderRSC Advances, 2017,7, 42738-492022-06-12代华平
42Independent Clinical Factors Relevant to Prognosis of Patients with Idiopathic Pulmonary Fibrosis.Med Sci Monit.?2019 Jun 5;25:4193-4201.2022-06-12代华平
43IL-25/IL-33/TSLP contributes to idiopathic pulmonary fibrosis: Do alveolar epithelial cells and (myo)fibroblasts matter?Exp Biol Med (Maywood). 2020 May;245(10):897-901.2022-06-12代华平
44Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosisCell Res. 2020 Jun 16;1-162022-06-12代华平
45Possible association of idiopathic pulmonary hemosiderosis with rheumatoid arthritis: A case reportExp Ther Med. 2020 Sep; 20(3):2291-2297.2022-06-12代华平
46不同类型特发性间质性肺炎患者小气道病变的差异中华医学杂志2022-06-12代华平
47急性弥漫性肺浸润性改变的临床特征中华医学杂志2022-06-12代华平
48慢性阻塞性肺疾病与致纤维化型间质性肺疾病患者阻塞性睡眠呼吸暂停对比研究中国实用内科杂2022-06-12代华平
49氢气在医学五大领域研究进展创伤与急危重病医学2022-06-12代华平
50当间质性肺疾病遇到新型冠状病毒肺炎:挑战与对策中华结核和呼吸杂志2022-06-12代华平
51Mass Spectrometry-based Proteomics in Acute Respiratory Distress Syndrome: A Powerful Modality for Pulmonary Precision MedicineChinese Medical Journal.2022-06-12代华平
52 Ouabain ameliorates bleomycin induced pulmonary fibrosis by inhibiting proliferation and promoting apoptosis of lung fibroblastsAm J Transl Res. 2018 Sep 15;10(9):2967-2974.2022-06-12代华平
53二甲双胍对博来霉素诱导的小鼠肺纤维化的作用中华医学杂志2022-06-12代华平
54Serum?prealbumin?is a?prognostic?indicator?in ?idiopathic pulmonary?fibrosisClin Respir J. 2019 Aug;13(8):493-4982022-06-12代华平
55Single-cell RNA sequencing profiling of the effects of aging on alveolar stem cellsSci China Life Sci. 2019 Aug;62(8):1028-10372022-06-12代华平
56 Single-Cell Transcriptomics Reveals Peripheral Immune Responses in Anti-Synthetase Syndrome-Associated Interstitial Lung DiseaseFront Immunol. 2022,13:804034.2022-06-12代华平
57吸入性三联药物治疗慢性阻塞性肺疾病的研究进展中华结核和呼吸杂志2022-06-12代华平
58特发性肺纤维化合并肺癌的研究进展国际呼吸杂志2022-06-12代华平
59纤维化间质性肺疾病——早期识别与干预国际呼吸杂志2022-06-12代华平
60Phosphatase and tensin homolog deleted on chromosome 10 contributes to phenotype transformation of fibroblasts in idiopathic pulmonary fibrosis via multiple pathways.Exp Biol Med .2022-06-12代华平
61Incidence and radiologic-pathological features of lung cancer in idiopathic pulmonary fibrosis.Clin Respir J. 2018 Apr;12(4):1320-1360.2022-06-12代华平
62The profibrotic effect of downregulated Na,K-ATPase 1 subunit in alveolar epithelial cells during lung fibrosisInt J Mol Med. 2019 Jul;44(1):273-2802022-06-12代华平
63Quantitative analysis of high-resolution computed tomography features of idiopathic pulmonary fibrosis: a structure-function correlation studyQUANTITATIVE IMAGING IN MEDICINE AND SURGERY2023-07-10代华平
64Chest wall muscle mass depletion is related to certain pulmonary functions and diseases in patients with bronchiectasisCHRONIC RESPIRATORY DISEASE 2023-07-10代华平
65Construction and validation of prognostic nomograms for elderly patients with metastatic non-small cell lung cancerCLINICAL RESPIRATORY JOURNAL2023-07-10代华平
66Construction and validation of prognostic nomograms for elderly patients with metastatic non-small cell lung cancerCLINICAL RESPIRATORY JOURNAL2023-07-10代华平
67Every road leads to Rome: therapeutic effect and mechanism of the extracellular vesicles of human embryonic stem cell-derived immune and matrix regulatory cells administered to mouse models of pulmonary fibrosis through different routesSTEM CELL RESEARCH & THERAPY2023-07-10代华平
68Serum Osteopontin, KL-6, and Syndecan-4 as Potential Biomarkers in the Diagnosis of Coal Workers'' Pneumoconiosis: A Case-Control StudyPHARMACOGENOMICS & PERSONALIZED MEDICINE 2023-07-10代华平
69Lung shrinking assessment on HRCT with elastic registration technique for monitoring idiopathic pulmonary fibrosisEUROPEAN RADIOLOGY 2023-07-10代华平
70The Potential Diagnostic Biomarkers for the IgG Subclass in Coal Workers'' PneumoconiosisJOURNAL OF IMMUNOLOGY RESEARCH2023-07-10代华平
71Expert Consensus on the Diagnosis and Treatment of Anticancer Drug-Induced Interstitial Lung DiseaseCURRENT MEDICAL SCIENCE 2023-07-10代华平
72Incidence and risk factors of venous thrombotic events in patients with interstitial lung disease during hospitalizationTHROMBOSIS JOURNAL2023-07-10代华平
73A Mouse Model of Pulmonary Fibrosis Induced by Nasal Bleomycin NebulizationJOVE-JOURNAL OF VISUALIZED EXPERIMENTS 2023-07-10代华平
74Case report: Corticosteroid-resistant acute fibrinous and organizing pneumonia with myelodysplastic syndromeFRONTIERS IN MEDICINE2023-07-10代华平
75Idiopathic pulmonary fibrosis disease progression: a dynamic quantitative chest computed tomography follow-up analysisQUANTITATIVE IMAGING IN MEDICINE AND SURGERY2023-07-10代华平
76The early and late intervention effects of collagen-binding FGF2 on elastase-induced lung injuryBIOMEDICINE & PHARMACOTHERAPY?2023-07-10代华平
77Malignancies in Patients with Interstitial Lung Diseases: A Single Center Observational StudyJOURNAL OF CLINICAL MEDICINE2023-07-10代华平
78d Chest Wall Motion in People with Normal Pulmonary Function: A Study with Free-Breathing Dynamic MRIJOURNAL OF CLINICAL MEDICINE 2023-07-10代华平
79Blood monocyte counts as a prognostic biomarker and predictor in Chinese patients with idiopathic pulmonary fibrosisFRONTIERS IN MEDICINE2023-07-10代华平
80IL-17A promotes lung fibrosis through impairing mitochondrial homeostasis in type II alveolar epithelial cellsJOURNAL OF CELLULAR AND MOLECULAR MEDICINE2023-07-10代华平
81The potential role of interleukin (IL)-25/IL-33/thymic stromal lymphopoietin (TSLP) on the pathogenesis of idiopathic pulmonary fibrosisCLINICAL RESPIRATORY JOURNAL2023-07-10代华平
82USP13 Deficiency Impairs Autophagy and Facilitates Age-related Lung FibrosisAMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY 2023-07-10代华平
83A transcriptomics-based meta-analysis identifies a cross-tissue signature for sarcoidosisFRONTIERS IN MEDICINE2023-07-10代华平
84Extensive Pulmonary Cyst Formation in Erdheim-Chester DiseaseAMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 2023-07-10代华平
85The associations of radiological features of high-resolution computed tomography with the outcomes of transbronchial cryobiopsy in interstitial lung diseases: A cohort studyFRONTIERS IN MEDICINE 2023-07-10代华平
86Small airway dysfunction in Chinese patients with idiopathic pulmonary fibrosisBMC PULMONARY MEDICINE2023-07-10代华平
87Three-dimensional ultrashort echo time magnetic resonance imaging in assessment of idiopathic pulmonary fibrosis, in comparison with high-resolution computed tomographyQUANTITATIVE IMAGING IN MEDICINE AND SURGERY2023-07-10代华平
88特发性肺纤维化患者报告结局:健康相关生活质量量表中国实用内科杂志2023-07-10代华平
89MRI在评价呼吸力学中的研究进展中国医学影像学杂志 2023-07-10代华平
90进展性纤维化间质性肺疾病的诊治进展临床内科杂志2023-07-10代华平
91人工智能在间质性肺疾病评价中的应用进展中国医学影像学杂志 2023-07-10代华平
92淋巴管肌瘤病生物标志物研究新进展中国临床新医学 2023-07-10代华平
93Feature Article: IL-25 contributes to lung fibrosis by directly acting on alveolar epithelial cells and fibroblastsExp Biol Med (Maywood). 2019 Jun;244(9):770-7802022-06-12代华平
94Clinical features and prognosis of microscopic polyangiitis with usual interstitial pneumonia compared with idiopathic pulmonary fibrosis.Clin Respir J. 2019 Jul;13(7):460-466.?2022-06-12代华平
95Water-Soluble C-60 Protects Against Bleomycin-Induced Pulmonary Fibrosis in MiceInt J Nanomedicine. 2020 Mar 31; 15: 2269–22762022-06-12代华平
96Direct medical costs of hospitalized patients with idiopathic pulmonary fibrosis in a tertiary hospital in ChinaCHINESE MEDICAL JOURNAL,2020,133(20):2498-2500.2022-06-12代华平
97A novel macrolide derivative ameliorates smoke-induced inflammation and emphysema by inhibiting NF-kappa B activationAMERICAN JOURNAL OF TRANSLATIONAL RESEARCH,2021,13(3):1209-1220.2022-06-12代华平
98Feasibility and Mechanism Analysis of Shenfu Injection in the Treatment of Idiopathic Pulmonary FibrosisRONTIERS IN PHARMACOLOGY,2021,12.2022-06-12代华平
99Telomere shortening impairs alveolar regenerationCell Prolif.2022 Mar 11;e13211.2022-06-12代华平
100特发性肺纤维化急性加重诊断和治疗中国专家共识中华医学杂志2022-06-12代华平
101Fibrinolytic system related to pulmonary arterial pressure and lung function of patients with idiopathic pulmonary fibrosis.Clin Respir J. 2017 Sep;11(5):640-647.2022-06-12代华平
102Eosinophilic BronchitisThe NEW ENGLAND JOURNAL of MEDICINE. 2017 Aug 31;377(9):8732022-06-12代华平
103Hydrogen inhalation attenuated bleomycin-induced pulmonary fibrosis by inhibiting transforming growth factor-beta 1 and relevant oxidative stress and epithelial-to-mesenchymal transitionExp Physiol. 2019 Dec;104(12):1942-19512022-06-12代华平
104不同类型特发性间质性肺炎患者胶原与血管生成相关因子的表达差异实用医学杂志2022-06-12代华平
105富勒烯C60对博来霉素诱导的小鼠肺纤维化的影响中华医学杂志2022-06-12代华平
106Metformin ameliorates bleomycin-induced pulmonary fibrosis in mice by suppressing IGF-1 Am J Transl Res. 2020 ;12(3):940-949. 2022-06-12代华平
107The accuracy of electromagnetic navigation bronchoscopy compared to fluoroscopy in navigation of transbronchial lung cryobiopsy in patients with interstitial lung diseaseBMC PULMONARY MEDICINE2024-03通讯作者
108The tolerability and efficacy of antifibrotic therapy in patients with idiopathic pulmonary fibrosis: Results from a real-world studyPULMONARY PHARMACOLOGY & THERAPEUTICS2024-03通讯作者
109Crazy-Paving Pattern in Pulmonary SarcoidosisNEW ENGLAND JOURNAL OF MEDICINE2024-02通讯作者
110Mesenchymal Stem Cells-Derived Exosomes Alleviate Acute Lung Injury By Inhibiting Alveolar Macrophage PyroptosisSTEM CELLS TRANSLATIONAL MEDICINE2024-02通讯作者
111Prevalence and Types of Comorbidities in Pneumoconiosis - China, 2018-2021CHINA CDC WEEKLY2023-09通讯作者
112Assessment of lung deformation in patients with idiopathic pulmonary fibrosis with elastic registration technique on pulmonary three-dimensional ultrashort echo time MRIINSIGHTS INTO IMAGING2024-01通讯作者
113External validation of the GAP model in Chinese patients with idiopathic pulmonary fibrosisCLINICAL RESPIRATORY JOURNAL2023-09通讯作者
114Evaluation of the Clinical Value of KL-6 and Tumor Markers in Primary Sjogren''s Syndrome Complicated with Interstitial Lung DiseaseJOURNAL OF CLINICAL MEDICINE2023-08通讯作者
115Interleukin-17A plays a key role in pulmonary fibrosis following Propionibacterium acnes-induced sarcoidosis-like inflammationEXPERIMENTAL BIOLOGY AND MEDICINE2023-07通讯作者
116Imbalanced distribution of regulatory T cells and Th17.1 cells in the peripheral blood and BALF of sarcoidosis patients: relationship to disease activity and the fibrotic radiographic phenotypeFRONTIERS IN IMMUNOLOGY2023-07通讯作者
117Clinical characteristics of hypersensitivity pneumonitis: non-fibrotic and fibrotic subtypesCHINESE MEDICAL JOURNAL2023-12通讯作者
118Elastic Registration Algorithm Based on Three-dimensional Pulmonary MRI in Quantitative Assessment of Severity of Idiopathic Pulmonary FibrosisJOURNAL OF THORACIC IMAGING2023-11通讯作者
119Association of family sequence similarity gene 13A gene polymorphism and interstitial lung disease susceptibility: A systematic review and meta-analysisMOLECULAR GENETICS & GENOMIC MEDICINE2023-11通讯作者
120结节病样肉芽肿动物模型的研究进展中国病理生理杂志2023-12通讯作者
121间质性肺疾病多学科讨论:现状、问题与对策国际呼吸杂志2023-11第一作者
  • 科研获奖Research Awards


  • 研究成果Research Findings
# 成果类型 项目/专利/新品种名称
1作为主创人员获得授权的发明专利和新品种人工气道阻塞/窒息报警装置
2作为主创人员获得授权的发明专利和新品种联合培养细胞的微流控芯片
3作为主创人员获得授权的发明专利和新品种一种肺灌洗管路
4作为主创人员获得授权的发明专利和新品种一种多功能动物实验操作台
5作为主创人员获得授权的发明专利和新品种一种可调长度可吸痰的气切套管扣
6作为主创人员获得授权的发明专利和新品种一种带导向插入孔的储氧面罩
7出版高水平专著移植感染
8出版高水平专著间质性肺疾病
9出版高水平专著呼吸病学新进展
10出版高水平专著内科学(第9版)
11出版高水平专著临床路径释义,呼吸疾病分册
12出版高水平专著呼吸病学(第三版)
13出版高水平专著国家卫生健康委员会住院医师规范化培训规划教材—内科学 呼吸与危重症医学分册(第2版)
14出版高水平专著呼吸与危重症医学2018-2019
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