导师风采
张传宝
个人信息
Personal Information
- 性别：男
- 导师类型：博士生导师
- 职称：研究员
- 该职称任职时间：2014
联系方式
Contact Information
- 所属院系：国家卫生健康委临床检验中心
- 所属专业：
- 邮箱 : cbzhang@nccl.org.cn
- 工作电话 : 010-58115050
个人简介
Personal Profile
研究员，博士生导师；国家卫生健康委临床检验中心副主任。 社会兼职包括： 中国医院协会临床检验专业委员会副主任委员兼秘书长，中国医学装备协会 现场快速检测（POCT）装备技术分会 副会长；《中华检验医学杂志》编委，《检验医学杂志》编委，《临床检验杂志》常务编委。
团队简介
Team Profile
待补充更新
- 研究方向Research Directions
临床检验质量管理，临床生化检验标准化
- 在校研究生Current Graduate Students
硕士研究生 6 名，博士研究生 0 名
- 科研项目Research Projects
| # | 项目名称 | 起止日期 | 金额 | 项目类型 | 本人角色 |
|---|---|---|---|---|---|
| 1 | 老年人群临床常用检验项目参考区间的建立与应用研究 | 2022-12-26 —— 2025-12 | 300.0 | 主持在研的国家或省部级科研项目 | 主持者 |
| 2 | 免疫抑制剂、维生素B、类固醇激素参考测量程序建议与验证 | 2024-01 —— 2024-12 | 300万元 | 主持的企业/行业委托重大项目 | 主持 |
- 发表论文Papers
| # | 论文题目 | 期刊名称 | 发表年份 | 论文署名 |
|---|---|---|---|---|
| 1 | Investigation of the quantitative detection of serum Helicobacter pylori antibody in clinical laboratories in China | .J Clin Lab Anal | 2023-01 | 张传宝 |
| 2 | Prevalence of methylmalonic acidemia among newborns and the clinical-suspected population: a meta-analyse | The Journal of Maternal-Fetal & Neonatal Medicine | 2022-12 | 张传宝 |
| 3 | A Simple and Accurate Measurement Procedure for Serum Chloride by Ion Chromatography and Evaluation of Bias of Six Common Used Ion Selective Electrode Methods in China | Clinical Laboratory | 2018-09 | 张传宝 |
| 4 | Therapeutic drug monitoring status of four common antibiotics: vancomycin, meropenem, linezolid and teicoplanin | Scandinavian Journal of Clinical and Laboratory Investigation | 2023-11 | 张传宝 |
| 5 | A simple method for rapid screening and diagnosis of common organic acidemias: quantitative detection of serum and urine organic acid profles based on liquid chromatography tandem mass spectrometry | Analytical and Bioanalytical Chemistry | 2023-11 | 张传宝 |
| 6 | The establishment of LC-MS/MS assays-specific reference intervals for serum folates and its application in evaluating FA-supplemented folate deficiency patients: Appeals for a suitable and individualized supplementation | Clinica Chimica Acta | 2022-12 | 张传宝 |
| 7 | Measurement of serum 17α- hydroxyprogesterone using isotope dilution liquid chromatography tandem mass spectrometry candidate reference method and its application on method evaluation | Clin Chem Lab Med | 2020-11 | 张传宝 |
| 8 | Commutability of reference materials for alkaline phosphatase measurements | SCAND J CLIN LAB INV | 2020-09 | 张传宝 |
| 9 | Evaluation of the Bias of Serum Magnesium Measurements and the Commutability of Processed Materials | Clin. Lab | 2022-06-15 | 张传宝 |
| 10 | Commutability of external quality assessment materials for serum sodium and potassium measurements | Clin Chem Lab Med | 2019-03 | 张传宝 |
| 11 | Analysis of current status of quantitative detection of biomarkers for liver fibrosis in Clinical labs in China | J Clin Lab Anal | 2022-05 | 张传宝 |
| 12 | Icaritin inhibits CDK2 expression and activity to interfere with tumor progression | iScience | 2022-08 | 张传宝 |
| 13 | A Rapid, Simple, Trace, Cost-Effective, and High-Throughput Stable Isotope-Dilution Liquid Chromatography–Tandem Mass Spectrometry Method for Serum Methylmalonic Acid Quantification and Its Clinical Applications | Diagnostics | 2022-09 | 张传宝 |
| 14 | A candidate reference method and multiple commutable control materials for serum 25‐hydroxyvitamin D measurement in Journal of Clinical Laboratory Analysis has the following publication status | J Clin Lab Anal | 2022-12 | 张传宝 |
| 15 | The spectrum of plasma renin activity and hypertension diseases: Utility, outlook, and suggestions | J Clin Lab Anal | 2022-10 | 张传宝 |
| 16 | Ligand binding assay-related underestimation of 25-hydroxyvitamin D in pregnant women exaggerates the prevalence of vitamin D insufficiency | Clin Chem Lab Med | 2023-01 | 张传宝 |
| 17 | wo comments for the curent commutability assessment | Clin Chem Lab Med | 2022-09 | 张传宝 |
| 18 | Performance of HDL-C measurements assessed by a 4-year trueness-based EQA/PT program in China | Clin Chem Lab Med | 2022-09 | 张传宝 |
| 19 | Commutability Assessment of Processed Human Plasma Samples for Normetanephrine and Metanephrine Measurements Based on the Candidate Reference Measurement Procedure | Ann Lab Med | 2022-09 | 张传宝 |
| 20 | Comparison of four different immunoassays and a rapid isotope-dilution liquid chromatography-tandem mass spectrometry assay for serum folate | Clin Chem Lab Med | 2022-08 | 张传宝 |
| 21 | Development of a designated comparison method for alkaline phosphatase measurements and its application to evaluating routine methods | Scandinavian Journal of Clinical and Laboratory Investigation | 2021-03 | 张传宝 |
| 22 | Measurement of serum progesterone by isotope dilution liquid chromatography tandem mass spectrometry: a candidate reference method and its application to evaluating immunoassays | Anal Bioanal Chem | 2019-02 | 张传宝 |
| 23 | Preparation, stability and commutability of candidate reference materials for lactate dehydrogenase (LDH) | Clinical Biochemistry | 2021-02 | 张传宝 |
| 24 | Current Status of Serum Insulin and C-Peptide Measurement in Clinical Laboratories: Experience from 94 Laboratories in China. | Ann Lab Med | 2022-07 | 张传宝 |
| 25 | Evaluation of serum electrolytes measurement through the 6-year trueness veri？cation program in China | Clin Chem Lab Med | 2020-07 | 张传宝 |
| 26 | Performance of electrolyte measurements assessed by a trueness verification program | Clin Chem Lab Med | 2016-08 | 张传宝 |
| 27 | Structural Analysis of the 5'-Flanking Region of Human Alpha-Fetoprotein Encoding Gene | Molecular Biology | 2022-11 | 张传宝 |
| 28 | Commutability Assessment of Candidate External Quality Assessment Materials for Aminotransferase Activity Measurements Based on Different Approaches in China | Ann Lab Med | 2021-01 | 张传宝 |
| 29 | Alpha-fetoprotein accelerates the progression of hepatocellular carcinoma by promoting Bcl-2 gene expression through an RA-RAR signaling pathway | J Cell Mol Med | 2020-12 | 张传宝 |
| 30 | The potential for isotope dilution-LC-MS/MS to improve laboratory measurement of C-peptide: Reasons and critical determinants. | Journal of Mass Spectrometry and Advances in the Clinical Lab | 2021-08 | 张传宝 |
| 31 | Assessment of enzyme measurement procedures in China through a truenes verification program | Clinca Chimica Acta | 2016-10 | 张传宝 |
| 32 | Commutability of external quality assessment materials for serum magnesium and calcium measurements | SCAND J CLIN LAB INV | 2019-10 | 张传宝 |
| 33 | Hepatitis B virus X protein upregulates alpha-fetoprotein to promote hepatocellular carcinoma by targeting miR-1236 and miR-329 | J Cell Biochem | 2020-03 | 张传宝 |
| 34 | Determination of serum calcium levels by 42Ca isotope dilution inductively coupled plasma mass spectrometry | Clin Chem Lab Med | 2017-11 | 张传宝 |
| 35 | Effects of calcium dobesilate(CaD) interference on serum creatinine measurements: a national External Quality Assessment (EQA)-based educational survey of drug-laboratory test interactions | Clin Chem Lab Med | 2020-07 | 张传宝 |
| 36 | Laboratory practice of organic acid analysis based on gas chromatography–mass spectrometry in China | Journal of Laboratory Medicine | 2021-09 | 张传宝 |
| 37 | Commutability of possible external quality assessment materials for progesterone measurement | Clinical Biochemistry | 2021-01 | 张传宝 |
| 38 | A candidate reference method for serum calcium measurement by inductively coupled plasma mass spectrometry | Clinca Chimica Acta | 2016-10 | 张传宝 |
| 39 | A candidate reference method for serum potassium measurement by inductively coupled plasma mass spectrometry | Clin Chem Lab Med | 2017-08 | 张传宝 |
| 40 | Current status of therapeutic drug monitoring for methotrexate, imatinib, paclitaxel in China | Clin Biochem | 2022-06 | 张传宝 |
| 41 | Inductively Coupled Plasma Mass Spectrometry as a Reference Method to Evaluate Serum Calcium Measurement Bias and the Commutability of Processed Materials during Routine Measurements | Chinese Medical Journal | 2018-07 | 张传宝 |
| 42 | Investigation and analysis of hemoglobin A1c measurement systems’ performance for 135 laboratories in China | Chinese Medical Journal | 2017-05 | 张传宝 |
| 43 | The consistency of aminotransferase analysis in China: a comparison of six mainstream aminotransferase routine methods and recalibration using human pooled serum preparations supplemented with human recombinant aminotransferases | Scandinavian Journal of Clinical and Laboratory Investigation | 2022-02 | 张传宝 |
| 44 | Comparison of four different immunoassays and a rapid isotope-dilution liquid chromatography-tandem mass spectrometry assay for serum folate | Clin Chem Lab Med | 2022-06 | 张传宝 |
| 45 | Quantitation of plasma metanephrines using isotope dilution liquid chromatography tandem mass spectrometry (ID-LC/MS/MS): a candidate reference measurement procedure and its application to evaluating routine ID-LC/MS/MS methods | Analytical and Bioanalytical Chemistry | 2021-12 | 张传宝 |
| 46 | Standardization evaluation of measurement procedures for serum uric acid by an 8-year accuracy-based external quality assessment program in China | Clin Chem Lab Med | 2019-03 | 张传宝 |
| 47 | Evaluation of serum alkaline phosphatase measurement through the 4-year trueness verification program in China | Clin Chem Lab Med | 2018-11 | 张传宝 |
| 48 | Commutability Assessment of Processed Human Plasma Samples for Normetanephrine and Metanephrine Measurements Based on the Candidate Reference Measurement Procedure | Ann Lab Med | 2022-09 | 张传宝 |
| 49 | Commutability assessment of candidate reference materials for plasma renin activity measurement: current challenges | Clinical Chemistry and Laboratory Medicine | 2023-07 | Zhenni Liu , Lizi Jin , Zijia Ma , Xiaerbanu Nizhamuding , Jie Zeng , Tianjiao Zhang , Jiangtao Zhang , Weiyan Zhou , Chuanbao Zhang |
| 50 | Abnormal kynurenine-pathway metabolites in gout: Biomarkers exploration based on orthogonal partial least squares-discriminant analysis | Clinica Chimica Acta | 2023-09 | Zhenni Liu , Lizi Jin , Zijia Ma , Xiaerbanu Nizhamuding , Jie Zeng , Tianjiao Zhang , Jiangtao Zhang , Weiyan Zhou , Chuanbao Zhang |
| 51 | Development of a designed comparison method based on isotope dilution liquid chromatography-tandem mass spectrometry for determining plasma renin activity and its clinical assessment of renin activity stability in plasma | Analytical Methods | 2023-01 | Zhenni Liu , Lizi Jin , Jiangtao Zhang , Tianjiao Zhang , Jie Zeng , Weiyan Zhou , Chuanbao Zhang |
| 52 | Quality management of the newborn screening network: the Chinese experience | Chinese Medical Journal | 2023-09 | Lizi Jin , Falin He , Chuanbao Zhang |
| 53 | Evaluation of imprecision in the different detection methods of Zn based on 5 years of data from an external quality assessment program in China | Journal of Trace Elements in Medicine and Biology | 2024-07 | Chao Zhang , Ying Yan , Chuanbao Zhang |
| 54 | Exploration of suitable external quality assessment materials for serum C-peptide measurement | Clinical Chemistry and Laboratory Medicine | 2023-05 | Yuhang Deng , Chao Zhang , Bingqiong Li , Jing Wang , Jie Zeng , Jiangtao Zhang , Tianjiao Zhang , Haijian Zhao , Weiyan Zhou , Chuanbao Zhang |
| 55 | An LC-MS/MS method for serum cystatin C quantification and its comparison with two commercial immunoassays | Clinical Chemistry and Laboratory Medicine | 2024-01 | Li Zhang, Xiaerbanu Nizhamuding, Hao Zheng, Jie Zeng, Xinyi Yuan, Zijia Ma, Weiyan Zhou, Chao Zhang, Tianjiao Zhang* and Chuanbao Zhang* |
| 56 | Imprecision remains to be improved in the measurement of serum cystatin C with heterogeneous systems | Clinical Chemistry and Laboratory Medicine | 2023-07 | Zeng Jie, Zhang Li, Zhang Jiangtao, Zhou Weiyan, Zhang Tianjiao, Wang Jing, Zhao Haijian and Zhang Chuanbao |
| 57 | An Accurate Isotope Dilution Liquid Chromatography-Tandem Mass Spectrometry Method for Serum C-Peptide and Its Use in Harmonization in China | Annals of Laboratory Medicine | 2023-07 | Yuhang Deng , Chao Zhang , Jing Wang , Jie Zeng , Jiangtao Zhang , Tianjiao Zhang , Haijian Zhao , Weiyan Zhou , Chuanbao Zhang |
| 58 | Poor comparability of plasma renin activity measurement in determining patient samples: the status quo and recommendations for harmonization Clinical Chemistry and Laboratory Medicine | Clinical Chemistry and Laboratory Medicine | 2023-04 | Zhenni Liu , Lizi Jin , Jie Zeng , Tianjiao Zhang , Jiangtao Zhang , Weiyan Zhou , Chuanbao Zhang |
| 59 | Application of serum pools in insulin harmonization: Commutability and stability | Annals of Clinical Biochemistry | 2023-05 | Yuhang Deng , Chao Zhang , Jing Wang , Jie Zeng , Jiangtao Zhang , Tianjiao Zhang , Haijian Zhao , Miao Li , Yang Zhao , Wei Gan , Yan Shao , Hongyuan Yu , Weiyan Zhou , Chuanbao Zhang |
| 60 | Evaluation of blood lead measurements by the 6-year external quality assessment program in China | Clinica Chimica Acta | 2023-04 | Chao Zhang, Ying Yan, Jie Zeng, Jiali Liu, Na Dong, Chuanbao Zhang |
| 61 | Altered neopterin and IDO in kynurenine metabolism based on LC-MS/MS metabolomics study: Novel therapeutic checkpoints for type 2 diabetes mellitus | Clinica Chimica Acta | 2024-03 | Zhenni Liu, Zijia Ma, Lizi Jin, Xiaerbanu Nizhamuding, Jie Zeng, Tianjiao Zhang, Jiangtao Zhang, Jing Wang, Haijian Zhao, Weiyan Zhou, Chuanbao Zhang |
| 62 | Insight into the status of plasma renin and aldosterone measurement: findings from 526 clinical laboratories in China | Clinical Chemistry and Laboratory Medicine | 2024-05 | Zhou Weiyan, DengYuhang, MaWenjun, ZhaoHaijian, WangKaijun, ZhangQian, GanWei, ChenWenxiang, CaiJun and ZhangChuanbao |
| 63 | The Role of IL‑6 in Neurodegenerative Disorders | Neurochemical Research | 2024-04 | Chen Shan, Chao Zhang, Chuanbao Zhang |
- 科研获奖Research Awards
| # | 获奖证书编号 | 奖项名称 | 获奖级别 | 获奖类别 | 获奖等级 | 获奖日期 | 颁奖单位 | 本单位是否为第一完成单位 | 完成单位排名 | 本人排序 | 备注 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2022-J-4-2-02-R01 | 我国重大慢病相关诊断标志物计量溯源体系的建立及全国标准化应用 | 省部级 | 其他省部级奖励 | 二等奖 | 2023-04-01 | 中国计量测试学会 | 是 | 1 | 1 | |
| 2 | 201202052U0101 | 临床生化检验项目参考体系的建立与应用 | 省部级 | 科技进步奖、哲学社科奖 | 二等奖 | 2012-12-18 | 中华医学会 | 是 | 1 | 2 | |
| 3 | 2010医-3-006 | 临床生化检验重要常规项目参考方法体系的建立与应用 | 省部级 | 科技进步奖、哲学社科奖 | 三等奖 | 2011-11-01 | 北京市人民政府 | 是 | 1 | 3 | |
| 4 | 2022-J06-2-12-R07 | 基于质谱技术的内分泌代谢病精准检测平台构建与推广应用 | 省部级 | 北京市科学技术奖 | 二等奖 | 2023-10-31 | 北京市人民医院 | 否 | 2 | 7 |
- 研究成果Research Findings
| # | 成果类型 | 项目/专利/新品种名称 |
|---|---|---|
| 1 | 获得省部级及以上科研奖励 | 2022年中国计量测试学会科学技术进步奖二等奖（第一完成人） |
| 2 | 获得新药研究成果 | 2023年北京市科学技术奖二等奖（第7完成人） |