导师风采
曹永彤

个人信息

Personal Information

  • 性别:男
  • 导师类型:博士生导师
  • 职称:教授、主任医师
  • 该职称任职时间:2014

联系方式

Contact Information

  • 所属院系:中日友好医院
  • 所属专业:临床检验诊断学
  • 邮箱 : caoyongtong92@sina.com
  • 工作电话 : 010-84205213

个人简介

Personal Profile

曹永彤,医学博士,教授、主任医师,博士研究生导师,中日友好医院检验科、输血科主任。相继从事心血管临床医疗、检验、输血治疗工作。现兼任中国中西医结合学会检验医学专业委员会候任主任委员、中华医学会检验分会委员、北京医学会检验医学分会候任主任委员、中华检验医学杂志副总编等。承担多项国家科技部支撑课题、国家自然科学基金课题、国家“863”专项及北京市首都特色专项课题。目前在研国家自然科学基金面上项目2项,发表学术论文累计163篇,其中SCI论文56篇,获发明专利11项,副主编/参编专著4部,牵头撰写《中国早期胃癌筛查检验技术专家共识》、《临床检验样本转运及保存规范化专家共识》、《县级医院医学检验科建设和管理指南》等3部指南和专家共识。

团队简介

Team Profile

曹永彤团队依托于北京市临床检验重点专科和国家呼吸医学中心、国家中西医结合医学中心,研究围绕临床诊疗中常见慢病和疑难病的生物标志物挖掘与验证,发挥临床检验诊断学在疾病诊断中的作用。主要研究方向:慢性肾病及心血管疾病诊断标志物的临床应用及基础研究,具体包括:Lp-PLA2/LPC作为糖尿病肾脏疾病内皮功能紊乱标志物的临床价值及其机制研究;FTO通过m6A修饰LINC00921调控细胞铁死亡在糖尿病心肌梗死中的临床价值及机制研究。研究团队有博导和硕导各1名,在读博士生和硕士生共5名。

  • 研究方向Research Directions
①检验医学研究新技术与新方法;②心血管疾病临床与基础研究;③糖尿病肾病标志物研究
  • 在校研究生Current Graduate Students

硕士研究生 1 名,博士研究生 3 名

  • 科研项目Research Projects
# 项目名称 起止日期 金额 项目类型 本人角色
1FTO通过m6A修饰LINC00921调控细胞铁死亡在糖尿病心肌梗死中的临床价值及机制研究2023-01-01 —— 2026-1252万元主持在研的国家或省部级科研项目主持人
  • 发表论文Papers
# 论文题目 期刊名称 发表年份 论文署名
1EDTA plasma in glass and polyethylene terephthalate tubes is suitable for measurement of B-type natriuretic peptide on the Mindray CL-6000iANNALS OF CLINICAL BIOCHEMISTRY2023-09通讯作者
2Fast and Sensitive Detection of SARS-CoV-2 Nucleic Acid Using a Rapid Detection System Free of RNA ExtractionINTERNATIONAL JOURNAL OF ANALYTICAL CHEMISTRY2023-01通讯作者
3Persistent increase of carbohydrate antigen 19-9 with an unknown reason: A seven-year follow-up caseJOURNAL OF CLINICAL LABORATORY ANALYSIS2022-12通讯作者
4Association of ABCC2 polymorphism with clopidogrel response in Chinese patients undergoing percutaneous coronary interventionFRONTIERS IN PHARMACOLOGY2022-10通讯作者
5Case report: First case of pemetrexed plus cisplatin-induced immune hemolytic anemia in a patient with lung adenocarcinomaFRONTIERS IN MEDICINE2022-08通讯作者
6Rapid detection of the irinotecan-related UGT1A128 polymorphism by asymmetric PCR melting curve analysis using one fluorescent probeJOURNAL OF CLINICAL LABORATORY ANALYSIS2022-08通讯作者
7The ceRNA Crosstalk between mRNAs and lncRNAs in Diabetes Myocardial InfarctionDISEASE MARKERS2022-05通讯作者
8A novel method for early detection of colorectal cancer based on detection of methylation of two fragments of syndecan-2 (SDC2) in stool DNABMC GASTROENTEROLOGY2022-04通讯作者
9A Novel Stool Methylation Test for the Non-Invasive Screening of Gastric and Colorectal CancerFRONTIERS IN ONCOLOGY2022-03通讯作者
10Analysis of the relationship between phenotypes and genotypes in 60 Chinese patients with propionic acidemia: a fourteen-year experience at a tertiary hospitalORPHANET JOURNAL OF RARE DISEASES2022-03通讯作者
11Association of AGTR1 A1166C and CYP2C9*3 Gene Polymorphisms with the Antihypertensive Effect of ValsartanINTERNATIONAL JOURNAL OF HYPERTENSION2022-03通讯作者
12Relationship between Body Roundness Index and Risk of Type 2 Diabetes in Japanese Men and Women: A Reanalysis of a Cohort StudyINTERNATIONAL JOURNAL OF ENDOCRINOLOGY2021-12通讯作者
13Globular adiponectin inhibits osteoblastic differentiation of vascular smooth muscle cells through the PI3K/AKT and Wnt/beta-catenin pathwayJOURNAL OF MOLECULAR HISTOLOGY2021-10通讯作者
14Susceptibility of ApoB and PCSK9 Genetic Polymorphisms to Diabetic Kidney Disease Among Chinese Diabetic PatientsFRONTIERS IN MEDICINE2021-04通讯作者
15Association of Apolipoprotein E Polymorphisms and Risks of Ischemic Stroke in Chinese Patients with Type 2 Diabetes MellitusJOURNAL OF DIABETES RESEARCH2021-01通讯作者
16Short-term biological variation and Reference change values of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine and 8-oxo-7,8-dihydroguanosineJOURNAL OF CLINICAL LABORATORY ANALYSIS2020-12通讯作者
17A Linear Relationship Between a Body Shape Index and Risk of Incident Type 2 Diabetes: A Secondary Analysis Based on a Retrospective Cohort Study in JapanDIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY2020-06通讯作者
18Association of Epoxide Hydrolase 2 Gene Arg287Gln with the Risk for Primary Hypertension in ChineseINTERNATIONAL JOURNAL OF HYPERTENSION2020-02通讯作者
19The Dose-Response Relationship between Gamma-Glutamyl Transferase and Risk of Diabetes Mellitus Using Publicly Available Data: A Longitudinal Study in JapanINTERNATIONAL JOURNAL OF ENDOCRINOLOGY2020-02通讯作者
20Characteristics of women infected with human papillomavirus in a tertiary hospital in Beijing China, 2014-2018BMC INFECTIOUS DISEASES2019-07通讯作者
21Genetically elevated circulating homocysteine concentrations increase the risk of diabetic kidney disease in Chinese diabetic patientsJOURNAL OF CELLULAR AND MOLECULAR MEDICINE2019-04通讯作者
22Interaction of MTHFR C677T polymorphism with smoking in susceptibility to diabetic nephropathy in Chinese men with type 2 diabetesJOURNAL OF HUMAN GENETICS2019-01通讯作者
23Regulation of soluble epoxide hydrolase in renal-associated diseases: insights from potential mechanisms to clinical researches.FRONTIERS IN ENDOCRINOLOGY2024-02通讯作者
24Normal triglyceride concentration and the risk of diabetes mellitus type 2 in the general population of ChinaFRONTIERS IN ENDOCRINOLOGY2024-02通讯作者
25Development of a Novel Multiplex PCR Method for the Rapid Detection of SARS-CoV-2, Influenza A Virus, and Influenza B VirusINTERNATIONAL JOURNAL OF ANALYTICAL CHEMISTRY2024-02通讯作者
26Serum circPRDM5 as a novel diagnostic biomarker for acute myocardial infarctionGENE2024-03通讯作者
27Tangshen formula improves diabetic nephropathy in STZ-induced diabetes rats fed with hyper-methionine by regulating the methylation status of kidneyCLINICAL EPIGENETICS2024-01通讯作者
28Experimental Characteristics of Patients with Newly Diagnosed Multiple MyelomaALTERNATIVE THERAPIES IN HEALTH AND MEDICINE2023-11通讯作者
29A novel assay based on DNA melting temperature for multiplexed identification of SARS-CoV-2 and influenza A/B virusesFRONTIERS IN MICROBIOLOGY2023-12通讯作者
30CircRNA and ferroptosis in human disease: Insights for new treatmentsANIMAL MODELS AND EXPERIMENTAL MEDICINE2023-12通讯作者
31Role of HLA class I and II alleles in susceptibility to ankylosing spondylitis in Chinese HanJOURNAL OF CLINICAL LABORATORY ANALYSIS2023-12通讯作者
32Discrimination of SARS-CoV-2 omicron variant and its lineages by rapid detection of immune-escape mutations in spike protein RBD using asymmetric PCR-based melting curve analysisVIROLOGY JOURNAL2023-08通讯作者
33Severe autoimmune hemolytic anemia complicating hereditary spherocytosis treated successfully with glucocorticoids and cyclosporine: a case reportHEMATOLOGY2023-12通讯作者
34高密度脂蛋白量和质在动脉粥样硬化中的临床应用中华检验医学杂志2023-07通讯作者
35中国早期胃癌筛查检验技术专家共识中华检验医学杂志2023-04第一作者
36临床检验样本转运及保存规范化专家共识中华检验医学杂志2023-03通讯作者
37县级医院医学检验科建设和管理指南中华检验医学杂志2022-07第一作者
38冠心病患者血清CTRP3与Lp-PLA2水平监测的临床价值分析中华检验医学杂志2021-07通讯作者
39动脉粥样硬化性心血管疾病风险评估中进一步脂质检测与应用中华检验医学杂志2021-07通讯作者
402型糖尿病患者载脂蛋白E基因多态性与心肌梗死的相关性中华检验医学杂志2021-10通讯作者
41EPHX2 rs751141变异位点对肾脏微炎症的影响及其分子机制研究首都医科大学学报2021-10通讯作者
42核酸快速检测系统在新型冠状病毒检测中的应用评价中华预防医学杂志2021-02通讯作者
43肺移植患者术中输血的关联因素分析及输血对患者预后的影响分析解放军医学院学报2021-10通讯作者
44载脂蛋白E基因多态性与2型糖尿病患者发生脑梗死的相关性研究中华检验医学杂志2020-02通讯作者
45血管紧张素转换酶基因多态性与2型糖尿病肾病的相关性研究中华检验医学杂志2019-02通讯作者
46A sensitive LC-MS/MS method for the quantification of serum epoxyeicosatrienoic and dihydroxyeicosatrienoic acids in the identification of diabetic kidney diseaseANALYTICAL AND BIOANALYTICAL CHEMISTRY2025-05通讯作者
47Comparative urine proteomic study involving papillary thyroid carcinoma and benign thyroid nodulesFRONTIERS IN ONCOLOGY2025-04通讯作者
48New insights in the treatment of DKD: recent advances and future prospectsBMC NEPHROLOGY2025-02通讯作者
49A mammary gland secretion function exploratory study based on a quantitative comparison between milk and serumMOLECULAR AND CELLULAR BIOCHEMISTRY2025-05通讯作者
50Early blood pressure drop predicts renal function deterioration and mortality in ICU patients with liver failure: a retrospective cohort studyMEDICINA INTENSIVA2025-03通讯作者
51The Analysis of Plasma Proteomics for Luminal A Breast CancerCANCER MEDICINE2024-12通讯作者
52Association between estimated glucose disposal rate and cardiovascular mortality across the spectrum of glucose tolerance in the US populationDIABETES OBESITY & METABOLISM2024-12通讯作者
53The utility of methylmalonic acid, methylcitrate acid, and homocysteine in dried blood spots for therapeutic monitoring of three inherited metabolic diseasesFRONTIERS IN NUTRITION2024-06通讯作者
54血清钙结合蛋白S100A9与特发性肺纤维化患者肺功能的相关性研究中华检验医学杂志2025-03通讯作者
55凝血项目参考区间建立中直接法与间接法的比较及应用中华预防医学杂志2025-03通讯作者
56衰老相关分泌表型在特发性肺纤维化中的研究进展中华检验医学杂志2024-10通讯作者
57尿液蛋白质组学对间质性肺病诊断价值中华检验医学杂志2024-10通讯作者
58基于检验指标构建多参数模型在特发性肺纤维化临床评估中的应用中华检验医学杂志2024-10通讯作者
59特发性肺纤维化诊断与预后生物标志物研究进展中华检验医学杂志2024-10通讯作者
  • 科研获奖Research Awards


  • 研究成果Research Findings
# 成果类型 项目/专利/新品种名称
1作为主创人员获得授权的发明专利和新品种一种一次性真空采血管保存盒
2作为主创人员获得授权的发明专利和新品种一种人ABCC2基因多态性检测的引物设计方法及试剂盒
3作为主创人员获得授权的发明专利和新品种一种流式细胞检测前的样本避光实验盒
4作为主创人员获得授权的发明专利和新品种一种基于胶乳增强免疫比浊法的检测试剂及其制备方法和试剂盒
5作为主创人员获得授权的发明专利和新品种一种荧光微球和抗体的偶联方法以及免疫层析试纸条
6作为主创人员获得授权的发明专利和新品种免疫反应干扰物及应用
7作为主创人员获得授权的发明专利和新品种同时检测n种目标基因的荧光实时检测系统、方法、多重引物、试剂盒
8作为主创人员获得授权的发明专利和新品种一种改良型微量试剂瓶
9作为主创人员获得授权的发明专利和新品种用于检测线粒体m.3243A>G突变率的引物对双探针组合物及其试剂盒与方法
10作为主创人员获得授权的发明专利和新品种一种检测UGT1A1基因多态性的试剂及检测方法
11出版高水平专著国家卫生健康委员会住院医师规范化培训规划教材配套精选习题集:检验医学科分册
12出版高水平专著检验医学病例与临床思维分析(检验医学科住院医技师规范化培训用书)
13出版高水平专著分子诊断标准化操作程序(第2版)