导师风采
斯建勇

个人信息

Personal Information

  • 性别:男
  • 导师类型:博士生导师
  • 职称:研究员
  • 该职称任职时间:20070711

联系方式

Contact Information

  • 所属院系:药用植物研究所
  • 所属专业:生药学
  • 邮箱 : jysi@implad.ac.cn
  • 工作电话 : 01057833299

个人简介

Personal Profile

斯建勇2000/09-2004/07 协和医科大学, 生药学,博士。1995/09-1998/07协和医科大学,生药学,硕士。1981/09-1985/07 西安医科大学,药学, 学士。工作经历:1987/01-至今 中国医学科学院药用植物研究所,任天然药物化学研究中心研究员,研究中心副主任,博士生导师、新疆中药民族药研究所客座研究员。科技部创新基金评审专家、卫生部食品新资原评审专家,广西柳州市政府科技顾问等。 研究方向天然药物药效物质基础及中药质量控制方法研究中药创新药物临床前药学研究 主持或参加科研项目项目情况1. “重大新药创制”科技重大专项—降脂中药5类新药“木豆总芪降脂胶囊研究”的研制(2009ZX09103-341),2008-2011,主持人。2.“重大新药创制”科技重大专项—综合性新药研究开发技术大平台(2009ZX09301-003)单元平台4-3,2009-2012,负责人。3. “重大新药创制”科技重大专项—综合性新药研究开发技术大平台(2009ZX09301-002)单元平台1-27,2012-2015,负责人。4. 国家自然基金课题“新疆阿魏种子抗肿瘤作用的物质基础及作用机理研究”(81460661)50万,2015-2018,负责人。5. 国家自然基金--新疆珍稀植物阿魏内生真菌与共生机制及药效物质生成相关性研究,(2015-2018年)主要参加者6.中国医学科学院医学与健康科技创新工程--含吡咯里西啶生物碱的中药安全风险评估及预警,2018-2021,负责人.

团队简介

Team Profile

待补充更新

  • 研究方向Research Directions
生药学,中药学
  • 在校研究生Current Graduate Students

硕士研究生 2 名,博士研究生 -1 名

  • 科研项目Research Projects


  • 发表论文Papers
# 论文题目 期刊名称 发表年份 论文署名
1Cryptoporic acid S, a new drimane-type sesquiterpene ether of isocitric acid from the fruiting bodies of Cryptoporus volvatusJournal of Asian Natural Products Research2022-06-02斯建勇
2Sesquiterpene coumarins from seeds of Ferula sinkiangensisFitoterapia2022-06-02斯建勇
3Two new sesquiterpene coumarins from the seeds of Ferula sinkiangensisPhytochem Lett2022-06-02斯建勇
4基于UPLC-MS /MS同时测定番泻叶中吡咯里西啶生物碱的含量中国现代中药2022-06-02斯建勇
5天山假狼毒地上部分化学成分研究天然产物研究与开发2022-06-02斯建勇
6Antidepressant activity of an aqueous extract from okra seedsRSC Advances2022-06-02斯建勇
7Novel Triterpenoid Alkaloids With Their Potential Cytotoxic Activity From the Roots of Siraitia grosvenoriiFrontiers in Chemistry2022-06-02斯建勇
8Analysis of pyrrolizidine alkaloids in Eupatorium fortunei Turcz. and their in vitro neurotoxicityFood and Chemical Toxicology2022-06-02斯建勇
9Simultaneous Determination and Risk Assessment of Pyrrolizidine Alkaloids in Artemisia capillaris Thunb. by UPLC-MS/MS Together with ChemometricsMolecules2022-06-02斯建勇
10A new terpene coumarin microbial transformed by Mucor polymorphosporus induces apoptosis of human gastric cancer cell line MGC-803Archives of Pharmacal Research2022-06-02斯建勇
11Apoptosis induction and cell cycle arrest induced by Sinkiangenone B,a novel phenylpropanoid derivative from the resin of Ferula sinkiangensis K.M.shenRSC Advances2022-06-02斯建勇
12Antiinflammatory and Analgesic Activities of Ethanol Extract and Isolated Compounds from Millettia pulchraBiol Pharm Bull2022-06-02斯建勇
13Two New Coumarins from the Leaves of PhellodendronamurenseSOJ Pharmacy & Pharmaceutical Sciences2022-06-02斯建勇
14An unusual sesquiterpene coumarin from the seeds of Ferula sinkiangensisJournal of asian natural Products research2022-06-02斯建勇
15基于 UPLC/Q-TOF/MS和网络药理学研究甘草渣活性部位治疗溃疡性 结肠炎的潜在机制西北药学杂志2022-06-02斯建勇
16化学计量学辅助分析罗布麻中的黄酮类成分西北药学杂志2022-06-02斯建勇
17响应曲面法优化新疆阿魏种子总倍半萜香豆素提取工艺中国现代中药2022-06-02斯建勇
18Glycyrrhetinic Acid Maintains Intestinal Homeostasis via HuRFrontiers in Pharmacology2022-06-02斯建勇
19Synergistic Anti-tumor Activity and Mechanisms of Total Glycosides from Cimicifuga Dahurica in Combination with CisplatinCHIN J INTEGR MED2022-06-02斯建勇
20Licoflavone B, an isoprene flavonoid derived from licorice residue, relieves dextran sodium sulfate-induced ulcerative colitis by rebuilding the gut barrier and regulating intestinal microfloraEuropean Journal of Pharmacology2022-06-02斯建勇
21The Regulatory Effects of Licochalcone A on the Intestinal Epithelium and Gut Microbiota in Murine ColitisMOLECULES2022-06-02斯建勇
22The Inhibition of Gastric Cancer Cells’ Progression by 23,24-Dihydrocucurbitacin E through Disruption of the Ras/Raf/ERK/MMP9 Signaling PathwayMolecules2022-06-02斯建勇
23Antiviral effects of ergosterol peroxide in a pig model of porcine deltacoronavirus (PDCoV) infection involves modulation of apoptosis and tight junction in the small intestineVeterinary Research2022-06-02斯建勇
24Determination of Toxic Pyrrolizidine Alkaloids in Traditional Chinese Herbal Medicines by UPLC-MS/MS and Accompanying Risk Assessment for Human HealthMolecules2022-06-02斯建勇
25葫芦烷型降三萜类化合物的研究进展中草药2022-06-02斯建勇
26美洲大蠊化学成分及生物活性的研究进展现代生物医学进展2022-06-02斯建勇
27隐孔菌子实体化学成分的研究中国现代中药2022-06-02斯建勇
28附子总碱及其模拟炮制品对大鼠离体心脏的毒性作用中国实验方剂学杂志2022-06-02斯建勇
29麦角甾醇过氧化物抑制猪繁殖与呼吸综合征病毒复制试验中国兽医杂志2022-06-02斯建勇
30康复新液 HPLC 指纹图谱建立及6种成分测定中成药2022-06-02斯建勇
31新疆阿魏种子化学成分的研究中草药2022-06-02斯建勇
32Quantitative analysis of pyrrolizidine alkaloids in Gynura procumbens by liquid chromatography–tandem quadrupole mass spectrometry after enrichment by PCX solid-phase extractionInternational Journal of Environmental Analytical Chemistry2022-06-02斯建勇
33Chemical constituents from the fruiting bodies of Cryptoporus volvatusArchives of pharmacal research2022-06-02斯建勇
34一点红HPLC指纹图谱研究及咖啡酰奎宁酸类成分的含量测定中华中医药杂志2022-06-02斯建勇
35Inhibition of Ovalitenin A on Proliferation of Hela Cells via Apoptosis, G2/M Cell Cycle Arrest, and Down-regulation of COX-2Chinese Herbal Medicines2022-06-02斯建勇
36Oxidative stress suppression by luteolin-induced heme oxygenase-1 expressionToxicology and Applied Pharmacology2022-06-02斯建勇
37Inhibition of Ovalitenin A on Proliferation of Hela Cells via Apoptosis, G2/M Cell Cycle Arrest, and Down-regulation of COX-2Chinese Herbal Medicines2022-06-02斯建勇
38Sesquiterpene coumarins from Ferula sinkiangensis K.M.Shen and their cytotoxic activitiesPhytochemistry2022-06-02斯建勇
39Two new cryptoporic acid derivatives from the fruiting bodies of Cryptoporus volvatus.Phytochemistry Letters2022-06-02斯建勇
40天山假狼毒和瑞香狼毒叶中挥发性成分的分析研究新疆医科大学学报2022-06-02斯建勇
41康复新液化学成分研究中国现代中药2022-06-02斯建勇
42Chemical Constituents, Biological Activities, and Proposed Biosynthetic Pathways of Steroidal Saponins from Healthy Nutritious Vegetable—AlliumNutrients2023-07-10斯建勇
43Undescribed sesquiterpene coumarins from the aerial parts of Ferula sinkiangensis and their anti-inflammatory activities in lipopolysaccharide-stimulated RAW 264.7 macrophagesphytochemistry2023-07-10斯建勇
44新疆阿魏地上部位中的1对新的非对映异构体中国现代中药2023-07-10斯建勇
  • 科研获奖Research Awards


  • 研究成果Research Findings
# 成果类型 项目/专利/新品种名称
1作为主创人员获得授权的发明专利和新品种一种具有抗肿瘤作用的药物的制备和应用
2作为主创人员获得授权的发明专利和新品种一种具有神经保护作用的药物的制备和应用.
3作为主创人员获得授权的发明专利和新品种新疆阿魏种子中一种具有抗流感病毒作用的药物的应用
4作为主创人员获得授权的发明专利和新品种萜类香豆素类化合物在治疗胃癌方面的应
5作为主创人员获得授权的发明专利和新品种一种治疗心脑血管疾病的药物组合物及其制备方法
6作为主创人员获得授权的发明专利和新品种一种防治禽流感的药物及其制备方法