导师风采
樊赛军
个人信息
Personal Information
- 性别：男
- 导师类型：博士生导师
- 职称：教授
- 该职称任职时间：
联系方式
Contact Information
- 所属院系：放射医学研究所（天津）
- 所属专业：
- 邮箱 : fansaijun@irm-cams.ac.cn
- 工作电话 :
个人简介
Personal Profile
樊赛军，国家杰出青年，国务院政府特殊津贴获得者。中国医学科学院/北京协和医学院放射医学研究所副所长，协和长聘教授。天津市放射医学与核医学重点实验室主任。 中华预防医学会放射卫生专业委员会主任委员，中国抗癌协会肿瘤放射防护专业委员会主任委员，《国际放射医学核医学杂志》总编。 樊赛军长期从事肿瘤放射治疗增敏与防护药物、核辐射损伤救治和康复等方面的研发工作。樊赛军已在包括Science等在内的国内外杂志上发表论文460多篇，论文总引用次数超过13,800余次。已申请国家发明专利和实用新型专利62项，已获得授权专利36项。在2014-2020年连续七次入选爱思唯尔发布的中国高被引学者(Most Cited Chinese Researchers)榜单。
团队简介
Team Profile
待补充更新
- 研究方向Research Directions
放射医学防护、救治与康复的研究
- 在校研究生Current Graduate Students
硕士研究生 0 名，博士研究生 0 名
- 科研项目Research Projects
| # | 项目名称 | 起止日期 | 金额 | 项目类型 | 本人角色 |
|---|---|---|---|---|---|
| 1 | 核辐射损伤防治医药和器械研发与示范应用 | 2021-10-01 —— | 4800.0 | 主持者 | |
| 2 | 新型医疗技术和药械研发转化平台建设 | 2022-10-24 —— | 2400.0 | ||
| 3 | 微塑料影响放射性损伤及其机制研究 | 2023-01-01 —— | 52.0 | 主持者 |
- 发表论文Papers
| # | 论文题目 | 期刊名称 | 发表年份 | 论文署名 |
|---|---|---|---|---|
| 1 | Stable colonization of Akkermansia muciniphila educates host intestinal microecology and immunity to battle against inflammatory intestinal diseases | Experimental and Molecular Medicine | 2023-07-08 | 樊赛军 |
| 2 | The exciting encounter between lncRNAs and radiosensitivity in IR-induced DNA damage events | Molecular Biology Reports | 2023-07-08 | 樊赛军 |
| 3 | Social Hierarchy Dictates Intestinal Radiation Injury in a Gut Microbiota-Dependent Manner | International Journal of Molecular Sciences | 2023-07-08 | 樊赛军 |
| 4 | D-galactose protects the intestine from ionizing radiation-induced injury by altering the gut microbiome | Journal of Radiation Research | 2023-07-08 | 樊赛军 |
| 5 | High-fat diet alters the radiation tolerance of female mice and the modulatory effect of melatonin | Food & Function | 2023-07-08 | 樊赛军 |
| 6 | Biomodified Extracellular Vesicles Remodel the Intestinal Microenvironment to Overcome Radiation Enteritis | ACS Nano | 2023-07-08 | 樊赛军 |
| 7 | PET imaging of new target CDK19 in prostate cancer | European Journal of Nuclear Medicine and Molecular Imaging | 2023-07-08 | 樊赛军 |
| 8 | Sexual sexual dimorphism of gut microbiota dictates therapeutics efficacy of radiation injuries | Adv Sci (Weinh) | 2022-07-11 | 樊赛军 |
| 9 | Enzyme-instructed self-assembly of a novel histone deacetylase inhibitor with enhanced selectivity and anticancer efficiency | Biomater Sci | 2022-07-11 | 樊赛军 |
| 10 | Caloric restriction alleviates radiation injuries in a sex-dependent fashion | FASEB J | 2022-07-11 | 樊赛军 |
| 11 | 富天冬酰胺蛋白增强拟南芥辐射抗性的研究 | 国际放射医学核医学杂志 | 2022-07-11 | 樊赛军 |
| 12 | The effects of melatonin administration on intestinal injury caused by abdominal irradiation from mice | Int J Mol Sci | 2022-07-11 | 樊赛军 |
| 13 | Amelioration of whole abdominal irradiation-induced intestinal injury in mice with 3,3′-Diindolylmethane (DIM) | Free Radical Biology and Medicine | 2022-07-11 | 樊赛军 |
| 14 | Enhanced radiotherapy using photothermal therapy based on dual-sensitizer of gold nanoparticles with acid-induced aggregation | Nanomedicine-Nanotechnology Biology and Medicine | 2022-07-11 | 樊赛军 |
| 15 | Metformin fights against radiation-induced early developmental toxicity | Science of the Total Environment | 2022-07-11 | 樊赛军 |
| 16 | Activation of STAT3 and Bcl-2 and reduction of reactive oxygen species (ROS) promote radioresistance in breast cancer and overcome of radioresistance with niclosamide | Oncogene | 2022-07-11 | 樊赛军 |
| 17 | ASTL抗体中和ASTL对人宫颈癌ME-180细胞放射敏感性的影响 | 国际放射医学核医学杂志 | 2022-07-11 | 樊赛军 |
| 18 | Tetrabromobisphenol a exacerbates the overall radioactive hazard to zebrafish (Danio rerio) | Environmental Pollution | 2023-07-08 | 樊赛军 |
| 19 | CLPTM1L induces estrogen receptor β signaling-mediated radioresistance in non-small cell lung cancer cells | Cell Communication and Signaling | 2023-07-08 | 樊赛军 |
| 20 | Identification of Key Genes and Pathways Associated With Irradiation in Breast Cancer Tissue and Breast Cancer Cell Lines | Dose-Response | 2023-07-08 | 樊赛军 |
| 21 | Exosome is involved in total body irradiation-induced intestinal injury in mice | Acta Pharmacol Sin | 2022-07-11 | 樊赛军 |
| 22 | Mouse parabiosis model promotes recovery of lymphocytes in irradiated mice | Int J Radiat Biol | 2022-07-11 | 樊赛军 |
| 23 | Identification of odor biomarkers in irradiation injury urine based on headspace SPME-GC-MS | Int J Radiat Biol | 2022-07-11 | 樊赛军 |
| 24 | Gut microbiota-derived indole 3-propionic acid protects against radiation toxicity via retaining acyl-CoA-binding protein | Microbiome | 2022-07-11 | 樊赛军 |
| 25 | STAT5与肿瘤关系的研究进展 | 天津医药 | 2022-07-11 | 樊赛军 |
| 26 | 基于生物信息学筛选乳腺癌放疗抵抗相关微小RNA的研究 | 国际生物医学工程杂志 | 2022-07-11 | 樊赛军 |
| 27 | Low dose irradiation facilitates hepatocellular carcinoma genesis involving HULC | Molecular Carcinogenesis | 2022-07-11 | 樊赛军 |
| 28 | 藿香正气合剂对γ射线照射小鼠的防护作用研究 | 国际放射医学核医学杂志 | 2022-07-11 | 樊赛军 |
| 29 | hsa-miR-212 Modulates the Radiosensitivity of Glioma Cells by Targeting BRCA1 | Oncol Rep | 2022-07-11 | 樊赛军 |
| 30 | Quantitative proteomic analysis of the effects of melatonin treatment for mice suffered from small intestinal damage induced by γ-ray radiation | Int J Radiat Biol | 2022-07-11 | 樊赛军 |
| 31 | 应用生物信息学确定结直肠癌辐射抗性细胞的差异表达基因 | 国际放射医学核医学杂志 | 2022-07-11 | 樊赛军 |
| 32 | Hydrogen-water ameliorates radiation-inducedgastrointestinal toxicity via MyD88's effects onthe gut microbiota | Experimental and Molecular Medicine | 2022-07-11 | 樊赛军 |
| 33 | Lncrna hotair enhances breast cancer radioresistance through facilitating hspa1a expression via sequestering mir-449b-5p | Thorac Cancer | 2022-07-11 | 樊赛军 |
| 34 | Increased activation of cGAS-STING pathway enhances radiosensitivity of non-small cell lung cancer cells | Thorac Cancer | 2022-07-11 | 樊赛军 |
| 35 | The Oncoprotein HBXIP promotes human breast cancer growth through down-regulating p53 via miR-18b/MDM2 and pAKT/MDM2 pathways | Acta Pharmacol Sin | 2022-07-11 | 樊赛军 |
| 36 | Elevated BTG2 improves the radiosensitivity of non‐small cell lung cancer (NSCLC) through apoptosis | Thorac Cancer | 2022-07-11 | 樊赛军 |
| 37 | CLPTM1L induces estrogen receptor β signaling-mediated radioresistance in non-small cell lung cancer cells | Cell Communication and Signaling | 2022-07-11 | 樊赛军 |
| 38 | HJC0152 suppresses human non-small-cell lung cancer by inhibiting STAT3 and modulating metabolism | Cell Proliferation | 2022-07-11 | 樊赛军 |
| 39 | 姜黄素对非小细胞肺癌细胞A549和H460放射敏感性的影响 | 国际放射医学核医学杂志 | 2022-07-11 | 樊赛军 |
| 40 | 组织基质金属蛋白酶抑制剂-2的表达纯化及活性鉴定 | 生物工程学报 | 2022-07-11 | 樊赛军 |
| 41 | MiR-148a对肺癌细胞放射敏感性的影响 | 国际放射医学核医学杂志 | 2022-07-11 | 樊赛军 |
| 42 | FOXO4-DRI多肽增加非小细胞肺癌细胞放射敏感性研究 | 中华放射医学与防护杂志 | 2022-07-11 | 樊赛军 |
| 43 | Commensal microbiota in the digestive tract: a review of its roles in carcinogenesis and radiotherapy | Cancer Biol Med | 2022-07-11 | 樊赛军 |
| 44 | Gut Microbiota Metabolite Fights Against Dietary Polysorbate 80-Aggravated Radiation Enteritis | Frontiers in Microbiology | 2022-07-11 | 樊赛军 |
| 45 | MiR-145 modulates the radiosensitivity of non-small cell lung cancer cells by suppression of TMOD3 | Carcinogenesis | 2022-07-11 | 樊赛军 |
| 46 | 白藜芦醇对辐射致小肠损伤的防护作用 | 国际生物医学工程杂志 | 2022-07-11 | 樊赛军 |
| 47 | Low-intensity exercise modulates gut microbiota to fight against radiation-induced gut toxicity in mouse models | Front Cell Dev Biol | 2022-07-11 | 樊赛军 |
| 48 | Gut microbiota modulates alcohol withdrawal-induced anxiety in mice | Toxicology Letters | 2022-07-11 | 樊赛军 |
| 49 | 自噬对肿瘤放射治疗疗效的影响 | 国际放射医学核医学杂志 | 2022-07-11 | 樊赛军 |
| 50 | 三磷酸腺苷对高剂量γ射线照射小鼠的防护作用研究 | 国际生物医学工程杂志 | 2022-07-11 | 樊赛军 |
| 51 | MiR-365 enhances the radiosensitivity of non-small cell lung cancer cells through targeting CDC25A | Biochem Biophys Res Commun | 2022-07-11 | 樊赛军 |
| 52 | Mouse serum protects against total body irradiation-induced hematopoietic system injury by improving the systemic environment after radiation | Free Radical Biology and Medicine | 2022-07-11 | 樊赛军 |
| 53 | 秀丽隐杆线虫识别辐射损伤小鼠尿液的研究 | 国际放射医学核医学杂志 | 2022-07-11 | 樊赛军 |
| 54 | Matrices and Affinity Ligands for Antibody Purification and Corresponding Applications in Radiotherapy | Biomolecules | 2022-07-11 | 樊赛军 |
| 55 | 日本福岛核废水排放入海的影响及建议措施 | 国际放射医学核医学杂志 | 2022-07-11 | 樊赛军 |
| 56 | FOXO4 peptide targets myofibroblast ameliorates bleomycin‐induced pulmonary fibrosis in mice through ECM‐receptor interaction pathway | J Cell Mol Med | 2022-07-11 | 樊赛军 |
| 57 | Oral microbiota affects the efficacy and prognosis of radiotherapy for colorectal cancer in mouse models | Cell Rep | 2022-07-11 | 樊赛军 |
| 58 | 禁食对137Cs γ射线照射诱导小鼠肠道辐射损伤的代谢组学研究 | 中华放射医学与防护杂志 | 2022-07-11 | 樊赛军 |
| 59 | 茶黄素对胸腺放射性损伤的防护作用 | 天津医药 | 2022-07-11 | 樊赛军 |
| 60 | 长链非编码RNA NBR2对乳腺癌细胞放射敏感性的影响 | 国际放射医学核医学杂志 | 2022-07-11 | 樊赛军 |
| 61 | Gut commensal derived-valeric acid protects against radiation injuries | Gut Microbes | 2022-07-11 | 樊赛军 |
| 62 | LncRNA调控肿瘤细胞辐射敏感性作用的研究进展 | 国际放射医学核医学杂志 | 2022-07-11 | 樊赛军 |
| 63 | 137Cs γ射线全身照射对小鼠骨髓细胞中circRNA m6A修饰谱的影响 | 中华放射医学与防护杂志 | 2022-07-11 | 樊赛军 |
| 64 | Cordycepin sensitizes breast cancer cells toward irradiation through elevating ROS production involving Nrf2. Toxicol Appl Pharmacol | Toxicology and applied pharmacology | 2022-07-11 | 樊赛军 |
- 科研获奖Research Awards
| # | 获奖证书编号 | 奖项名称 | 获奖级别 | 获奖类别 | 获奖等级 | 获奖日期 | 颁奖单位 | 本单位是否为第一完成单位 | 完成单位排名 | 本人排序 | 备注 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2019JB-2-061-R8 | 核辐射突发事件伤员诊断和救治方法的建立及应用 | 省部级 | 科技进步奖、哲学社科奖 | 二等奖 | 2020-01-22 | 天津市人民政府 | 是 | 1 | 8 |
- 研究成果Research Findings
| # | 成果类型 | 项目/专利/新品种名称 |
|---|---|---|
| 1 | 作为主创人员获得授权的发明专利和新品种 | DPP4抑制剂在防治辐射诱导骨髓抑制药物中的应用 |
| 2 | 作为主创人员获得授权的发明专利和新品种 | 一种盛放生物样本和生物试剂EP管的装置 |
| 3 | 作为主创人员获得授权的发明专利和新品种 | 含硝基咪唑基团的苯胺喹唑啉类化合物及其制备方法和应用 |
| 4 | 作为主创人员获得授权的发明专利和新品种 | 戊酸在制备用于预防和/或治疗肿瘤放疗副反应的药物中的用途 |
| 5 | 作为主创人员获得授权的发明专利和新品种 | 一类具有辐射防护作用的新化合物、其制备方法及其药物应用 |
| 6 | 作为主创人员获得授权的发明专利和新品种 | 一种药物组合物及其制备方法和用途 |
| 7 | 作为主创人员获得授权的发明专利和新品种 | 吲哚丙酸在制备用于预防和/或治疗肿瘤放疗副反应的药物中的用途 |