个人信息
Personal Information
联系方式
Contact Information
个人简介
Personal Profile
副研究员,博士生导师。从事共生微生态介导放射损伤修复与放疗增敏的基础与应用研究。入选国家高层次人才特殊支持计划青年拔尖人才、天津市杰出青年、天津市青年创优能手、中国辐射防护学会优秀青年科学家、天津市创新人才推进计划青年科技优秀人才、天津市高校 “131”创新型人才第二层次人选。以第一作者/通讯作者身份在Cell Reports、EMBO Molecular Medicine、Microbiome、Cancer Research、Advanced Science、Gut Microbes等杂志发表SCI论文三十余篇。授权国家发明专利七项。主持国家自然科学基金面上项目、青年项目等多项基金。
团队简介
Team Profile
待补充更新
硕士研究生 3 名,博士研究生 2 名
# | 项目名称 | 起止日期 | 金额 | 项目类型 | 本人角色 |
---|---|---|---|---|---|
1 | 国家高层次人才特殊支持计划青年拔尖人才 | 2021-12-01 —— | 140.0 | 主持在研的国家或省部级科研项目 | 主持者 |
2 | 天津市杰出青年科学基金 | 2020-10-01 —— | 60.0 | 主持在研的国家或省部级科研项目 | 主持者 |
3 | 皮肤微生物修复放射性皮肤损伤的基础与应用研究 | 2024-01 —— | 49 | 主持在研的国家或省部级科研项目 | 主持者 |
# | 论文题目 | 期刊名称 | 发表年份 | 论文署名 |
---|---|---|---|---|
1 | Oral microbiota affects the efficacy and prognosis of radiotherapy for colorectal cancer in mouse models. | Cell Rep | 2022-07-07 | 通讯作者 |
2 | Commensal microbiota in the digestive tract: a review of its roles in carcinogenesis and radiotherapy. | Cancer Biol Med | 2021-08 | 通讯作者 |
3 | Caloric restriction alleviates radiation injuries in a sex-dependent fashion. | FASEB J | 2021-08 | 通讯作者 |
4 | Ambient temperature structures the gut microbiota of zebrafish to impact the response to radioactive pollution. | Environ Pollut | 2022-01 | 通讯作者 |
5 | Gut Commensal Derived-Valeric Acid Protects against Radiation Injuries. | Gut Microbes | 2020-01 | 通讯作者 |
6 | Gut microbiota metabolite fights against dietary polysorbate 80-aggravated radiation enteritis. | Front Microbiol | 2020-06 | 通讯作者 |
7 | Gamma-irradiation fluctuates the mRNA N 6-methyladenosine (m 6 A) spectrum of bone marrow in hematopoietic injury. | Environ Pollut | 2021-09 | 通讯作者 |
8 | Metformin fights against radiation-induced early developmental toxicity. | Sci Total Environ | 2020-08 | 通讯作者 |
9 | SREBP1/FASN/cholesterol axis facilitates radioresistance in colorectal cancer. | FEBS Open Bio | 2021-05 | 通讯作者 |
10 | Gut Microbiota-Derived L-Histidine/Imidazole Propionate Axis Fights against the Radiation-Induced Cardiopulmonary Injury. | Int J Mol Sci | 2021-10 | 通讯作者 |
11 | Sexual dimorphism in gut microbiota dictates therapeutic efficacy of intravenous immunoglobulin on radiotherapy complications | J Adv Res | 2023-04 | 通讯作者 |
12 | Sexual dimorphism of gut microbiota dictates therapeutics efficacy of radiation injuries. | Adv Sci | 2019-08 | 通讯作者 |
13 | Low-Intensity Exercise Modulates Gut Microbiota to Fight Against Radiation-Induced Gut Toxicity in Mouse Models. | Front Cell Dev Biol | 2021-10 | 通讯作者 |
14 | Oral microbiota transplantation fights against head and neck radiotherapy-induced oral mucositis in mice. | Comput Struct Biotechnol J | 2021-10 | 通讯作者 |
15 | LncRNA HOTAIR enhances breast cancer radioresistance through facilitating HSPA1A expression via sequestering miR-449b-5p. | Thorac Cancer | 2020-07 | 通讯作者 |
16 | Cordycepin sensitizes breast cancer cells toward irradiation through elevating ROS production involving Nrf2. | Toxicol Appl Pharmacol | 2019-02 | 通讯作者 |
17 | Gut microbiota-derived indole 3-propionic acid protects against radiation toxicity via retaining acyl-CoA binding protein. | Microbiome | 2020-05 | 通讯作者 |
18 | Gut microbiota-derived PGF2α fights against radiation-induced lung toxicity through the MAPK/NF-κB pathway. | Antioxidants | 2021-12 | 通讯作者 |
19 | Roseburia intestinalis sensitizes colorectal cancer to radiotherapy through the butyrate/OR51E1/RALB axis. | Cell Rep | 2024-02 | 通讯作者 |
20 | Marasmius androsaceus mitigates depression-exacerbated intestinal radiation injuries through reprogramming hippocampal miRNA expression. | Biomed Pharmacother | 2023-07 | 通讯作者 |
21 | Stable colonization of Akkermansia muciniphila educates host intestinal microecology and immunity to battle against inflammatory intestinal diseases. | Exp Mol Med | 2023-01 | 通讯作者 |
22 | Social Hierarchy Dictates Intestinal Radiation Injury in a Gut Microbiota-Dependent Manner. | Int J Mol Sci | 2022-10 | 通讯作者 |
23 | 一种肠道微生物代谢产物混合物对肝癌的影响 | 微生物学报 | 2024-05 | 通讯作者 |
24 | 乳化剂吐温-80和丁酸对辐射诱导胆汁酸肠肝循环障碍的影响 | 中华放射医学与防护杂志 | 2021-05 | 通讯作者 |
无
# | 成果类型 | 项目/专利/新品种名称 |
---|---|---|
1 | 作为主创人员获得授权的发明专利和新品种 | 3. 一种药物组合物及其制备方法和用途; |
2 | 作为主创人员获得授权的发明专利和新品种 | 2. 吲哚丙酸在制备用于预防和/或治疗肿瘤放疗副反应的药物中的用途; |
3 | 作为主创人员获得授权的发明专利和新品种 | 1. 戊酸在制备用于预防和/或治疗肿瘤放疗副反应的药物中的用途 |
4 | 作为主创人员获得授权的发明专利和新品种 | 4. 包含正戊酸、吲哚丙酸和正丁酸钠的药物组合物的新用途; |