导师风采
金晶
个人信息
Personal Information
- 性别：女
- 导师类型：博士生导师
- 职称：主任医师
- 该职称任职时间：15
联系方式
Contact Information
- 所属院系：肿瘤医院
- 所属专业：
- 邮箱 : jinjing@csco.org.cn
- 工作电话 : 075566618168
个人简介
Personal Profile
金晶教授，博士生导师，中国医师协会结直肠肿瘤专业委员会放射治疗专业委员会主任委员，中国临床肿瘤学会（CSCO）胃癌专家委员会副主任委员，中国抗癌协会肿瘤放射治疗专业委员会常务委员。擅长消化系统肿瘤、乳腺癌、泌尿系统肿瘤、恶性淋巴瘤、软组织肿瘤等放射治疗。曾在国际最好的肿瘤专科医院美国MD安德森肿瘤中心进修学习，对国内外最新的放射治疗技术与药物治疗，如立体定向照射、图像引导放疗、质子/重离子放疗以及适形调强放疗、靶向治疗与免疫治疗有较深刻的了解和掌握。有独立诊断、处置疑难病例的能力，在国内外肿瘤专业杂志以第一作者/通讯作者发表百余篇论文，其中SCI文章三十余篇，如Journal of Oncology, JAMA子刊等，近5年以第一作者或通讯作者发表SCI论文近20篇，累计影响因子达108.378。多次获得中国医学科学院/北京协和医科大学以及北京市抗癌协会青年科技论文优秀奖，获得第一届深圳“最美科技工作者”称号。在消化道肿瘤放射治疗的医学实践和理论研究中，学术造诣高深，召集和组织来自全国的放疗同行，开展多项、多中心消化道肿瘤放化疗随机临床研究，取得丰硕成果，获得国际、国内相关领域认可，研究结果并被NCCN指南引用。以项目负责人获得包括国家自然科学基金、首都卫生发展科研专项、国家863计划项目、吴阶平医学基金会、卫生部临床学科重点项目等资助。国际会议发言10余次，国际会议壁报30余篇；在北美放射肿瘤年会获得best of ASTRO（ASTRO优秀论文）4次。
团队简介
Team Profile
待补充更新
- 研究方向Research Directions
消化道肿瘤的放射治疗和综合治疗,直肠癌放疗敏感性相关基础研究
- 在校研究生Current Graduate Students
硕士研究生 3 名，博士研究生 3 名
- 科研项目Research Projects
| # | 项目名称 | 起止日期 | 金额 | 项目类型 | 本人角色 |
|---|---|---|---|---|---|
| 1 | 基于危险度分层的直肠癌新辅助放化疗前瞻性、多中心、随机对照研究 | 2020-07-01 —— 2023-06-30 | 70.0 | 主持在研的国家或省部级科研项目 | 主持者 |
| 2 | 环状RNA circDNAJC3及其靶分子在直肠癌放疗敏感性调控中的机制研究 | 2021-01-01 —— 2024-12-31 | 55.0 | ||
| 3 | 局部晚期直肠癌新辅助治疗联合免疫治疗的临床研究及疗效预测 | 2024-01 —— 2027-12 | 200万元 | 主持在研的国家或省部级科研项目 | 主持人 |
- 发表论文Papers
| # | 论文题目 | 期刊名称 | 发表年份 | 论文署名 |
|---|---|---|---|---|
| 1 | Development and Validation of an MRI-Based Nomogram Model for Predicting Disease-Free Survival in Locally Advanced Rectal Cancer TreatedWith Neoadjuvant Radiotherapy. | Frontiers in Oncology | 2022-07-31 | 金晶 |
| 2 | Safety and efficacy of preoperative chemoradiotherapy in fit older patients with intermediate or locally advanced rectal cancer evaluated by comprehensive geriatric assessment: A planned interim analysis of a multicenter, phase II trial | Journal of Geriatric Oncology | 2022-06-01 | 金晶 |
| 3 | Preoperative Concurrent Chemoradiotherapy Versus Neoadjuvant Chemotherapy for Locally Advanced Gastric Cancer: Phase II Randomized Study | Frontiers in Oncology | 2022-07-07 | 金晶 |
| 4 | Assessment and validation of the internal gross tumour volume of gastroesophageal junction cancer during simultaneous integrated boost radiotherapy | Radiation Oncology | 2022-07-07 | 金晶 |
| 5 | Associations of genetic variations in mismatch repair genes MSH3 and PMS1 with acute adverse events and survival in patients with rectal cancer receiving postoperative chemoradiotherapy | Cancer Research and Treatment | 2022-07-07 | 金晶 |
| 6 | Response prediction and risk stratification of patients with rectal cancer after neoadjuvant therapy through an analysis of circulating tumour DNA | eBioMedicine | 2022-07-31 | 金晶 |
| 7 | Tomotherapy as an adjuvant treatment for gastroesophageal junction and stomach cancer may reduce bowel and bone marrow toxicity compared to intensity-modulated radiotherapy and volumetric-modulated arc therapy | Oncotarget | 2022-07-07 | 金晶 |
| 8 | Radiomics Analysis of Fat-Saturated T2-Weighted MRI Sequences for the Prediction of Prognosis in Soft Tissue Sarcoma of the Extremities and Trunk Treated With Neoadjuvant Radiotherapy | Frontiers in Oncology | 2022-07-31 | 金晶 |
| 9 | Patients with pathological stage N2 rectal cancer treated with early adjuvant chemotherapy have a lower treatment failure rate | BMC Cancer | 2022-07-07 | 金晶 |
| 10 | Nfatc1 colonic stem cells contribute to regeneration upon colitis | J Gastroenterol Hepatol | 2022-07-31 | 金晶 |
| 11 | The prognostic value of MRI-detected extramural vascular invasion (mrEMVI) for rectal cancer patients treated with neoadjuvant therapy: a meta-analysis | European Radiology | 2022-06-01 | 金晶 |
| 12 | Associations of Genetic Variations in MicroRNA Seed Regions With Acute Adverse Events and Survival in Patients With Rectal Cancer Receiving Postoperative Chemoradiation Therapy | International journal of radiation oncology, biology, physics | 2022-06-01 | 金晶 |
| 13 | Postoperative Chemoradiotherapy With Capecitabine and Oxaliplatin vs Capecitabine for Stage II to III Rectal Cancer: A Randomized Clinical Trial | JAMA Netw Open | 2022-06-01 | 金晶 |
| 14 | LncRNA and mRNA signatures associated with neoadjuvant chemoradiotherapy downstaging effects in rectal cancer | J Cell Biochem | 2022-06-01 | 金晶 |
| 15 | MiR-320b/RAD21 axis affects hepatocellular carcinoma radiosensitivity to ionizing radiation treatment through DNA damage repair signaling | Cancer Science | 2022-06-01 | 金晶 |
| 16 | MiR-92b targets p57kip2 to modulate the resistance of hepatocellular carcinoma (HCC) to ionizing radiation (IR) -based radiotherapy | Biomedicine & pharmacotherapy | 2022-06-01 | 金晶 |
| 17 | A prospective phase I study of hypo-fractionated neoadjuvant radiotherapy for locally advanced gastric cancer | BMC Cancer | 2022-06-01 | 金晶 |
| 18 | Down-staging depth score to predict outcomes in locally advanced rectal cancer achieving ypI stage after neoadjuvant chemo-radiotherapy versus denovo stage pI cohort: A propensity score-matched analysis | Chinese Journal of Cancer Research | 2022-06-01 | 金晶 |
| 19 | Multicenter, Randomized, Phase III Trial of Short-Term Radiotherapy Plus Chemotherapy Versus Long-Term Chemoradiotherapy in Locally Advanced Rectal Cancer (STELLAR) | Journal of Clinical Oncology | 2022-06-01 | 金晶 |
| 20 | Outcomes after hypofractionated stereotactic radiotherapy for colorectal cancer oligometastases | Journal of surgical oncology | 2022-06-01 | 金晶 |
| 21 | S-1 chemotherapy and intensity-modulated radiotherapy after D1/D2 lymph node dissection in patients with node-positive gastric cancer: a phase I/II study | British journal of cancer | 2022-06-01 | 金晶 |
| 22 | Efficacy and toxicity of capecitabine combined with intensity-modulated radiotherapy after D1/D2 lymph node dissection in patients with gastric cancer | World J GastrointestOncol | 2022-06-01 | 金晶 |
| 23 | Down-staging depth score could be a survival predictor for locally advanced gastric cancer patients after preoperative chemoradiotherapy | Chinese Journal of Cancer Research | 2022-06-01 | 金晶 |
| 24 | Preoperative versus postoperative chemo-radiotherapy for locally advanced gastric cancer: a multicenter propensity score-matched analysis | BMC Cancer | 2022-07-07 | 金晶 |
| 25 | Metastasis risk stratification and response prediction through dynamic viable circulating tumor cell counts for rectal cancer in a neoadjuvant setting | Cancer medicine | 2023-05 | 第一作者：刘文扬；通讯作者：金晶 |
| 26 | Wu YL, Liu W, Zhao T, Jin J. P4HA2 contributes to head and neck squamous cellcarcinoma progression and EMT through PI3K/AKT signaling pathway. Med Oncol. | Med Oncol | 2024-05 | 金晶 |
| 27 | Preoperative chemoradiotherapy in older patients with rectal cancer guided by comprehensive geriatric assessment within a multidisciplinary team-a multicenter phase II trial. | BMC Geriatr | 2024-01 | Wen-Yang, Liu., Yuan, Tang., Ning, Li., Yu, Tang., Yun-Jie, Cheng., Lin, Yang., Hui, Fang., Ning-Ning, Lu., Shu-Nan, Qi., Bo, Chen., Shu-Lian, Wang., Yong-Wen, Song., Yue-Ping, Liu., Ye-Xiong, Li., Zheng, Liu., Jian-Wei, Liang., Wei, Pei., Xi-Shan, Wang., Hai-Zeng, Zhang., Jun, Wang., Hai-Tao, Zhou., Jing, Jin. |
| 28 | The efficacy and safety of short-course radiotherapy followed by sequential chemotherapy and Cadonilimab for locally advanced rectal cancer: a protocol of a phase II study. | BMC Cancer | 2024-04 | Xu T, Feng L, Zhang W, Li H, Ma H, Abulimiti M, Tan Y, Deng F, Huang W, Zou S, Kang W, Jiang L, Wang Y, Hu C, Chen Y, Zhou H, Tang Y, Jin J. |
| 29 | A deep neural network predictor to predict the sensitivity of neoadjuvant chemoradiotherapy in locally advanced rectal cancer. Cancer Letters. | Cancer Letters. | 2024-01 | Liu Y, Shi J, Liu W, Tang Y, Shu X, Wang R, Chen Y, Shi X, Jin J, Li D. A |
| 30 | The short-term efficacy and safety of induction chemotherapy combined with PD-1 inhibitor or anti-EGFR in locoregionally advanced nasopharyngeal carcinoma. | Front Oncol, | 2023-05 | Xiang Xiaoyong., Chen Peng., Lan Fengming., Ma Li., Jin Jing., Zhang Ye. |
| 31 | Nomogram for predicting the overall survival of patients after D2/R0 resection and chemoradiotherapy for stage III gastric cancer or gastroesophageal junction cance | Radiation Medicine and Protection | 2023-09 | Jinming Shi, Wenzhe Kang, Songlin Gao , Wenyang Liu , Yuan Tang, Ning Li, Qiang Zeng, Huiying Ma, Haoyue Li, Yantao Tian, Jing Jin . |
| 32 | Xiang X, Ji Z, Jin J. Brachytherapy is an effective and safe salvage option for re-irradiation in recurrent glioblastoma (rGBM): A systematic review. | Radiother Oncol | 2023-11 | Xiang X, Ji Z, Jin J. |
| 33 | Chinese expert recommendations on management of hepatocellular carcinoma during COVID-19 pandemic: a nationwide multicenter survey. | HPB (Oxford) | 2022-03 | Zhao H, Zhou A, Zhou J, Bi X, Yan S, Jin J, Wei W, Li M, Gong C, Chen Q, Luo Z, Li N, Mao R, Chen X, Chen B, Zheng R, Zhao J, Han Y, Li Z, Che X, Tang Y, SunY, Huang Z, Zhang Y, Wang X, Zhang Y, Lu Z, Dang X, Song T, Liu C, Yue P, Yan D,Yue A, Zhang R, Luo S, Tan J, Zhang X, Bai X, Zhang X, He M, Xie Y, Wang W, Yang P, Yang Y, Zhang Y, Li Q, Peng T, Wang Z, Chen Y, Shang C, Liang Y, Zhang B,Zhang F, Wang L, Li D, Liu B, Zhu X, Hu Q, Chen M, Xiu D, Xia F, Zhang Y, Zeng Y, Mao Y, Li X, Ba Y, Liang T, Shen F, Liu L, Cai X, Zhou J, Cai J. |
| 34 | Genetic polymorphisms in genes regulating cell death and prognosis of patients with rectal cancer receiving postoperative chemoradiotherapy[J] | Cancer Biology & Medicine | 2023-09 | Hongxia Chen，Luxi Yin，Jie Yang，Ningxin Ren，Jinna Chen，Qixuan Lu，Ying Huang，Yanru Feng，Weihu Wang，Shulian Wang，Yueping Liu，Yongwen Song，Yexiong Li，Jing Jin，Wen Tan，Dongxin Lin |
| 35 | Adjuvant Chemoradiotherapy Versus Adjuvant Chemotherapy for Stage III Gastric or Gastroesophageal Junction Cancer After D2/R0 Resection. | Front. Oncol. | 2022-08 | Shi J, Kang W, Tang Y, Li N, Jiang L,Yang L, Wang S, Song Y, Liu Y,Fang H, Lu N, Qi S, Chen B, Li Y,Tian Y and Jin J✳ |
| 36 | Total neoadjuvant therapy for locally advanced gastric cancer and esophagogastric junction adenocarcinoma: study protocol for a prospective, multicenter, single-arm, phase II clinical trial. | BMC Gastroenterol | 2022-01 | Shi Jinming., Li Ning., Tang Yuan., Jiang Liming., Yang Lin., Wang Shulian., Song Yongwen., Liu Yueping., Fang Hui., Lu Ningning., Qi Shunan., Chen Bo., Li Ziyu., Liu Shixin., Wang Jun., Wang Wenling., Zhu Suyu., Yang Jialin., Li Yexiong., Zhao Dongbing. |
| 37 | Radiotherapy guidelines for rectal cancer in China (2020 Edition).Prac | Radiat Oncol. | 2022-01 | Shixin Liu, Jing Jin. |
| 38 | The safety of an MRI simulation-guided boost after short-course preoperative radiotherapy for unresectable rectal cancer (SUNRISE): interim analysis of a randomized phase II trial. | Radiat Oncol | 2022-04 | Liu Wen-Yang., Shi Jin-Ming., Li Ning., Wang Xin., Gao Yuan-Hong., Chi Yihebali., Sun Yong-Kun., Zhao Qing., Zhu Yong-Jian., Chen Hong-Da., Fang Hui., Lu Ning-Ning., Qi Shu-Nan., Chen Bo., Wang Shu-Lian., Song Yong-Wen., Liu Yue-Ping., Li Ye-Xiong., Liu Zheng., Zhou Hai-Tao., Liang Jian-Wei., Wang Xi-Shan., Zhang Hai-Zeng., Tang Yuan. |
| 39 | Genetic polymorphisms in genes regulating cell death and prognosis of patients with rectal cancer receiving postoperative chemoradiotherapy | Cancer Biology & Medicine | 2022-05 | Hongxia Chen，Luxi Yin，Jie Yang，Ningxin Ren，Jinna Chen，Qixuan Lu，Ying Huang，Yanru Feng，Weihu Wang，Shulian Wang，Yueping Liu，Yongwen Song，Yexiong Li，Jing Jin，Wen Tan，Dongxin Lin. |
- 科研获奖Research Awards
| # | 获奖证书编号 | 奖项名称 | 获奖级别 | 获奖类别 | 获奖等级 | 获奖日期 | 颁奖单位 | 本单位是否为第一完成单位 | 完成单位排名 | 本人排序 | 备注 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 201303041P0803 | 中华医学科技奖 | 国家级 | 其他国家级奖励 | 三等奖 | 2013-06-16 | 中华医学会 | 是 | 1 | 3 | |
| 2 | 2013医-2-010-03 | 北京市科学技术奖 | 省部级 | 省（市、自治区）政府自然科学奖、技术发明奖 | 二等奖 | 2014-01-08 | 北京市人民政府 | 是 | 1 | 3 | |
| 3 | 201202019P1003 | 中华医学科技奖 | 省部级 | 其他省部级奖励 | 三等奖 | 2013-01-27 | 中华医学会 | 是 | 1 | 3 | |
| 4 | -- | 华夏医学科技奖 | 省部级 | 其他省部级奖励 | 一等奖 | 2014-05-24 | 中国医疗保健国际交流促进会 | 是 | 1 | 3 | |
| 5 | -- | 北京抗癌协会第八届北京青年科技论文评选奖 | 省部级 | 其他省部级奖励 | 二等奖 | 2005-06-14 | 北京抗癌协会 | 1 | 1 | ||
| 6 | 2012医-3-011-03 | 北京市科学进步奖 | 省部级 | 省（市、自治区）政府自然科学奖、技术发明奖 | 三等奖 | 2013-02-22 | 北京市人民政府 | 1 | 3 |
- 研究成果Research Findings
| # | 成果类型 | 项目/专利/新品种名称 |
|---|---|---|
| 1 | 作为主创人员获得授权的发明专利和新品种 | 一种检测直肠癌放疗敏感性的环状RNA分子及其应用 |
| 2 | 出版高水平专著 | 结直肠癌肝转移外科治疗策略与实践 |
| 3 | 出版高水平专著 | 头颈恶性肿瘤的规范性治疗 |
| 4 | 出版高水平专著 | 现代肿瘤学第二版 |
| 5 | 出版高水平专著 | 恶性肿瘤规范化、标准化诊治丛书 |
| 6 | 出版高水平专著 | 肿瘤放射治疗学 |
| 7 | 出版高水平专著 | 放射肿瘤学—治疗策略与实施 |
| 8 | 出版高水平专著 | 胰腺癌，国家重大出版工程项目/中国常见癌症丛书第一版 |
| 9 | 出版高水平专著 | 肿瘤放射治疗学第四版 |
| 10 | 出版高水平专著 | 现代结肠、直肠及肛管区肿瘤学 |
| 11 | 出版高水平专著 | 肿瘤放射治疗手册 |
| 12 | 出版高水平专著 | 肿瘤外科学 基础、循证和新技术 |
| 13 | 出版高水平专著 | 直肠癌综合治疗问答 |