导师风采
于胜吉
个人信息
Personal Information
- 性别：男
- 导师类型：博士生导师
- 职称：主任医师
- 该职称任职时间：35
联系方式
Contact Information
- 所属院系：肿瘤医院
- 所属专业：
- 邮箱 : shengjiyu@126.com
- 工作电话 : 87788722
个人简介
Personal Profile
于胜吉，男，56岁。主任医师、博士生导师。 现为中国医学科学院肿瘤医院主任医师、教授、骨科主任。从事骨科临床工作30余年，擅长各种骨与软组织良、恶性肿瘤、腹膜后软组织肿瘤、皮肤肿瘤、骨转移癌的诊治，以及各种肿瘤切除后的组织修复与功能重建技术。 研究方向为骨与软组织肉瘤的临床与基础研究，包括骨转移癌的临床诊疗与分子机制、骨肉瘤干细胞在肿瘤生长中的发生发展研究等。在研课题6项，完成省部级课题3项，主编著作4部，主译著作4部，参编著作10部,自1998年以第一作者或通讯作者发表SCI期刊论文及中文核心期刊论文30余篇。 目前担任的学术职务：中国医药教育协会骨与软组织肿瘤专业委员会主任委员、中国抗癌学会肉瘤专业青年委员会主任委员、国家肿瘤微创治疗产业技术创新战略联盟专家委员会副主任委员、中国老年学和老年医学学会理事、北京肿瘤学会理事、中华医学会肿瘤学分会骨与软组织肿瘤学会委员、中华医学会北京分会骨肿瘤学组委员、中国医疗保健国际交流促进会软组织肿瘤分会常务委员、中国研究型医院学会骨科创新与转化专业委员会骨肿瘤学组常务委员、北京医学会手外科学分会常务委员、北京抗癌学会肉瘤专业委员会委员等。
团队简介
Team Profile
待补充更新
- 研究方向Research Directions
肿瘤学
- 在校研究生Current Graduate Students
硕士研究生 2 名，博士研究生 2 名
- 科研项目Research Projects
| # | 项目名称 | 起止日期 | 金额 | 项目类型 | 本人角色 |
|---|---|---|---|---|---|
| 1 | 软组织肉瘤多中心数据库的建立及诊治分析 | —— | 40.0 | 主持者 | |
| 2 | 建立人源化骨与软组织肉瘤类器官模型库用于精准生物治疗研究的探索 | —— | 78 | 主持在研的国家或省部级科研项目 | 主持人 |
- 发表论文Papers
| # | 论文题目 | 期刊名称 | 发表年份 | 论文署名 |
|---|---|---|---|---|
| 1 | Lower Expression of GBP2 Associated With Less Immune Cell Infiltration and Poor Prognosis in Skin Cutaneous Melanoma (SKCM) | JOURNAL OF IMMUNOTHERAPY | 2022-05-31 | 于胜吉 |
| 2 | Epithelioid sarcoma: A single-institutional retrospective cohort study of 36 cases | Journal of Orthopaedic Surgery | 2022-05-31 | 于胜吉 |
| 3 | Potential application of genomic profiling for the diagnosis and treatment of patients with sarcoma | Oncology Letters | 2022-05-31 | 于胜吉 |
| 4 | Inhibition of ATR-Chk1 signaling blocks DNA double-strand break repair and induces cytoplasmic vacuolization in metastatic osteosarcoma | Therapeutic Advances in Medical Oncology | 2022-05-31 | 于胜吉 |
| 5 | 环状RNA在肿瘤领域中的研究进展 | 癌症进展 | 2022-05-31 | 于胜吉 |
| 6 | 恶性外周神经鞘瘤的预后影响因素研究进展 | 癌症进展 | 2022-05-31 | 于胜吉 |
| 7 | miR-429 inhibits migration and invasion of breast cancer cells in vitro | INT J ONCOL | 2022-05-31 | 于胜吉 |
| 8 | 术中电子线放射治疗技术在肢体关节周围骨与软组织恶性肿瘤保肢手术中的应用 | 中华肿瘤杂志 | 2022-05-31 | 于胜吉 |
| 9 | PMEL as a Prognostic Biomarker and Negatively Associated With Immune Infiltration in Skin Cutaneous Melanoma (SKCM) | JOURNAL OF IMMUNOTHERAPY | 2022-05-31 | 于胜吉 |
| 10 | Clinical evaluation of percutaneous kyphoplasty for the management of osteoblastic-related metastatic vertebral lesions | ACADEMIC RADIOLOGY | 2022-05-31 | 于胜吉 |
| 11 | Effiacy of percutaneous vertebroplasty for the relief of osteoblastic spinal metastasis pain | Experimental and Therapeutic Medicine | 2022-05-31 | 于胜吉 |
| 12 | 躯干及四肢平滑肌肉瘤的临床特征及预后因素分析 | 重庆医学 | 2022-05-31 | 于胜吉 |
| 13 | 四肢和躯干II~III期未分化高级别多形性肉瘤的治疗及预后影响因素分析 | 中华肿瘤杂志 | 2022-05-31 | 于胜吉 |
| 14 | CDK7-dependent transcriptional addiction in bone and soft tissue sarcomas: Present and Future | Biochim Biophys Acta Rev Cancer | 2022-05-31 | 于胜吉 |
| 15 | Comparison of the clinical outcomes of percutaneous kyphoplasty for the management of osteolytic and osteoblastic-related metastatic vertebral lesions | Journal of NeuroInterventional Surgery | 2022-05-31 | 于胜吉 |
| 16 | Establishment and Characterization of a Novel Dedifferentiated Chondrosarcoma Cell Line DDCS2 | Cancer Control | 2022-05-31 | 于胜吉 |
| 17 | 术前18F氟代脱氧葡萄糖PET-CT诊断四肢及躯干皮肤黑色素瘤淋巴结转移的应用价值 | 中华肿瘤杂志 | 2022-05-31 | 于胜吉 |
| 18 | 射频消融联合经皮椎体成形治疗脊柱转移瘤的临床应用 | 中国骨与关节杂志 | 2022-05-31 | 于胜吉 |
| 19 | 前哨淋巴结活检术在肢体黑色素瘤治疗中的作用和意义 | 中华肿瘤杂志 | 2022-05-31 | 于胜吉 |
| 20 | Inhibition of CDK7-dependent transcriptional addiction is a potential therapeutic target in synovial sarcoma | BIOMEDICINE & PHARMACOTHERAPY | 2022-05-31 | 于胜吉 |
| 21 | 不明原因骨转移瘤的诊疗进展 | 癌症进展 | 2022-05-31 | 于胜吉 |
| 22 | 未分化多形性肉瘤的临床研究进展 | 癌症进展 | 2022-05-31 | 于胜吉 |
| 23 | 足踝部软组织肿瘤和骨肿瘤的临床病理特征及预后影响因素分析 | 中华肿瘤杂志 | 2022-05-31 | 于胜吉 |
| 24 | 椎体增强术及其联合应用治疗脊柱转移瘤的现状 | 中国肿瘤 | 2022-05-31 | 于胜吉 |
| 25 | 140例恶性外周神经鞘瘤的临床病理特征与预后分析 | 中华肿瘤杂志 | 2022-05-31 | 于胜吉 |
| 26 | Analysis of prognostic factors in 171 patients with myxofibrosarcoma of the trunk and extremities: a cohort study | Annals of Translational Medicine | 2022-05-31 | 于胜吉 |
| 27 | The landscape of gene mutations and clinical significance of tumor mutation burden in patients with soft tissue sarcoma who underwent surgical resection and received conventional adjuvant therapy | INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS | 2022-05-31 | 于胜吉 |
| 28 | Perforator Propeller Flap for Oncologic Reconstruction of Soft Tissue Defects in Trunk and Extremities | ANNALS OF PLASTIC SURGERY | 2022-05-31 | 于胜吉 |
| 29 | 四肢和关节附近软组织肉瘤术中电子线 放疗的并发症和近期疗效 | 中华肿瘤杂志 | 2022-05-31 | 于胜吉 |
| 30 | Molecular targeted therapy for advanced or metastatic soft tissue sarcoma | Cancer Control | 2022-05-31 | 于胜吉 |
| 31 | Factors associated with bone metastasis in breast cancer: a systematic review and meta-analysis | Annals of Palliative Medicine | 2022-05-31 | 于胜吉 |
| 32 | Dermatofibrosarcoma Protuberans: A Clinicopathologic and Therapeutic Analysis of 254 Cases at a Single Institution | DERMATOLOGIC SURGERY | 2022-05-31 | 于胜吉 |
| 33 | 应用高通量测序技术分析成人软组织肉瘤的基因变异情况 | 中华肿瘤杂志 | 2022-05-31 | 于胜吉 |
| 34 | 中国结直肠癌骨转移多学科综合治疗专家共识(2020版) | 中华结直肠疾病电子杂志 | 2022-05-31 | 于胜吉 |
| 35 | The long non-coding RNA CRNDE competed endogenously with miR-205 to promote proliferation and metastasis of melanoma cells by targeting CCL18 | CELL CYCLE | 2022-05-31 | 于胜吉 |
| 36 | 四肢与躯干侵袭性纤维瘤病的治疗与预后影响因素分析 | 中国骨与关节杂志 | 2022-05-31 | 于胜吉 |
| 37 | 弹力纤维瘤的诊断和治疗分析 | 癌症进展 | 2022-05-31 | 于胜吉 |
| 38 | C 臂引导下经皮椎体穿刺活检在胸腰椎转移瘤中的临床诊断价值 | 肿瘤学杂志 | 2022-05-31 | 于胜吉 |
| 39 | Clinicopathological Features and Prognosis of Malignant Peripheral Nerve Sheath Tumor：A Retrospective Study of 159 Cases from 1999 to 2016 | Oncotarget | 2022-05-31 | 于胜吉 |
| 40 | Undifferentiated Pleomorphic Sarcoma of the extremity and trunk: a retrospective cohort study of 166 cases in a large institution | Translational Cancer Research | 2022-05-31 | 于胜吉 |
| 41 | Schwann cells promote prevascularization and osteogenesis of tissue-engineered bone via bone marrow mesenchymal stem cell-derived endothelial cells | Stem Cell Research & Therapy | 2022-05-31 | 于胜吉 |
| 42 | MicroRNA-429 inhibits bone metastasis in breast cancer by regulating CrkL and MMP-9 | BONE | 2022-05-31 | 于胜吉 |
| 43 | 四肢躯干平滑肌肉瘤18例临床分析 | 中国综合临床 | 2022-05-31 | 于胜吉 |
| 44 | 股内侧间室软组织肉瘤的手术治疗效果 | 中华肿瘤杂志 | 2022-05-31 | 于胜吉 |
| 45 | 隔离肢体灌注治疗局部进展期软组织肉瘤 | 癌症进展 | 2022-05-31 | 于胜吉 |
| 46 | Patient-derived Tumour Organoids: A Bridge between Cancer Biology and Personalised Therapy | Acta Biomaterialia | 2022-07 | 于胜吉 |
| 47 | Cancer organoid co-culture model system: Novel approach to guide precision medicine | Frontiers in Immunology | 2023-01 | 于胜吉 |
| 48 | Transcription-associated cyclin-dependent kinase 12 (CDK12) as a potential target for cancer therapy | BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER | 2023-01 | 于胜吉 |
| 49 | Acral Lentiginous Melanoma: A Clinicoprognostic Study of 149 Cases at a Single Institution | AMERICAN SURGEON | 2023-09 | 于胜吉 |
| 50 | A Modification of the American Joint Committee on Cancer Nomogram for Undifferentiated Sarcoma With External Validation and Risk Stratification | AMERICAN SURGEON | 2023-10 | 于胜吉 |
| 51 | Comprehensive Analysis Reveals Prognostic and Therapeutic Immunity-Related Biomarkers for Pediatric Metastatic Osteosarcoma | Medicina-Lithuania | 2024-01 | 于胜吉 |
| 52 | CFLAR: A novel diagnostic and prognostic biomarker in soft tissue sarcoma, which positively modulates the immune response in the tumor microenvironment | Oncology Letters | 2024-02 | |
| 53 | Organoids derived from metastatic cancers: Present and future | Heliyon | 2024-04 | |
| 54 | Development of a nomogram for predicting cancer-specific survival in synovial sarcoma: Insights from SEER and a Chinese cohort study | Asian Journal of Surgery | 2024-05 | 于胜吉 |
| 55 | Hidden blood loss and its influencing factors after cement augmentation for vertebral metastasis | Heliyon | 2024-03 | 于胜吉 |
| 56 | Global, Regional, and National Incidence Trend Analysis of Malignant Skin Melanoma Between 1990 and 2019, and Projections Until 2034 | Cancer Control | 2024-01 | 于胜吉 |
| 57 | The efficacy of re-excision after unplanned excision for synovial sarcoma | Heliyon | 2023-12 | 于胜吉 |
| 58 | Can the Unipedicular Approach Replace Bipedicular Percutaneous Balloon Kyphoplasty for the Management of Metastatic Vertebral Lesions? | ACADEMIC RADIOLOGY | 2023-10 | 于胜吉 |
| 59 | Risk factors for pulmonary cement embolism after percutaneous vertebroplasty and radiofrequency ablation for spinal metastases | Frontiers in Oncology | 2023-05 | 于胜吉 |
| 60 | Clinical analysis of percutaneous kyphoplasty for spinal metastases in older adults with comorbidities | Journal of Geriatric Oncology | 2023-01 | 于胜吉 |
| 61 | The infuence of diverse bone cement distribution patterns for metastatic vertebral lesions after bilateral percutaneous kyphoplasty | BMC MUSCULOSKELETAL DISORDERS | 2022-07 | 于胜吉 |
- 科研获奖Research Awards
无
- 研究成果Research Findings
| # | 成果类型 | 项目/专利/新品种名称 |
|---|---|---|
| 1 | 出版高水平专著 | 腕关节外科 |
| 2 | 出版高水平专著 | 协和医生答疑丛书-骨与软组织肿瘤199个怎么办 |
| 3 | 出版高水平专著 | 中华医学百科全书. 临床医学 肿瘤学分卷 |
| 4 | 出版高水平专著 | 骨转移手册(患者指南) |
| 5 | 出版高水平专著 | 应对骨与软组织肿瘤专家谈 |
| 6 | 出版高水平专著 | 骨转移手册(医护专业人员版) |
| 7 | 出版高水平专著 | 骨与软组织肿瘤的治疗 |
| 8 | 出版高水平专著 | Dahlin骨肿瘤（第六版） |