导师风采
高树庚

个人信息

Personal Information

  • 性别:男
  • 导师类型:博士生导师
  • 职称:主任医师
  • 该职称任职时间:20080901

联系方式

Contact Information

  • 所属院系:肿瘤医院
  • 所属专业:肿瘤学
  • 邮箱 : gaoshugeng@cicams.ac.cn
  • 工作电话 : 87787150

个人简介

Personal Profile

高树庚,中国协和医科大学医学博士,主任医师、博士研究生导师,北京协和医学院长聘教授,享受国务院特殊津贴专家,国家卫生健康突出贡献中青年专家,全国对口支援新疆先进个人,北京协和医学院教学名师。现任国家癌症中心副主任、中国医学科学院肿瘤医院副院长。担任中华医学会胸心血管外科分会副主任委员兼秘书长、中国医师协会胸外科医师分会副会长兼总干事、北京医学会胸外科分会主任委员兼肺癌学组组长,《Journal of Thoracic Diseases》、《中华胸心血管外科杂志》、《中华胸部外科电子杂志》副主编,《中华外科杂志》、《中华肿瘤杂志》编委等学术职务,入选中国国家健康科普专家库第一批成员名单、AATS会员。

团队简介

Team Profile

待补充更新

  • 研究方向Research Directions
早期肺癌精准微创外科新技术的研发;新辅助免疫治疗在非小细胞肺癌患者中的个性化应用
  • 在校研究生Current Graduate Students

硕士研究生 3 名,博士研究生 6 名

  • 科研项目Research Projects
# 项目名称 起止日期 金额 项目类型 本人角色
1肺癌手术联合新辅助免疫治疗的评价体系和优选模式研究2021-12-01 —— 2024-11-302800.0主持在研的国家或省部级科研项目主持者
2肿瘤微创诊疗一体化医疗器械关键技术及应用的研究2021-10-01 —— 2025-12-313200.0主持在研的国家或省部级科研项目主持者
3新辅助免疫治疗非小细胞肺癌患者ctDNA甲基化动态演变研究2023-01-01 —— 2026-12-3170.6主持在研的国家或省部级科研项目主持者
4高龄患者周围 型早期非小细胞肺癌外科手术方式探索的多中心前瞻性临床研究2022-05-06 —— 2027-05-01100.0主持在研的国家或省部级科研项目主持者
  • 发表论文Papers
# 论文题目 期刊名称 发表年份 论文署名
1Preoperative systemic immune-inflammation index and prognostic nutritional index predict prognosis of patients with pulmonary neuroendocrine tumors after surgical resectionAnnals of Translational Medicine2022-05-31高树庚
2Integrated molecular characterization reveals potential therapeutic strategies for pulmonary sarcomatoid carcinomaNature Communications2022-05-31高树庚
3Different pathologic responses to neoadjuvant anti-PD-1 in primary squamous lung cancer and regional lymph nodesnpj Precision Oncology2022-05-31高树庚
4Clinical outcomes following an initial experience with a novel powered vascular stapler in video-assisted thoracoscopic lobectomies: results of a Chinese multi-center studyJournal of Thoracic Disease2022-05-31高树庚
5Society for Translational Medicine Expert Consensus on the prevention and treatment of postoperative pulmonary infection in esophageal cancer patientsJournal of Thoracic Disease2022-05-31高树庚
6mTOR up-regulation of BEX4 promotes lung adenocarcinoma cell proliferation by potentiating OCT4Biochemical and Biophysical Research Communications2022-05-31高树庚
7Worldwide burden and epidemiological trends of tracheal, bronchus, and lung cancer: A population-based studyEbioMedicine2022-05-31高树庚
8Genomic features and tumor immune microenvironment alteration in NSCLC treated with neoadjuvant PD-1 blockadenpj Precision Oncology2022-05-31高树庚
9Severe hypoglycemia and finger clubbing in a patient with a BRCA1 mutation in a solitary fibrous tumor: a case reportAnnals of Translational Medicine2022-05-31高树庚
10Preoperative systemic immune-inflammation index predicts survival and recurrence in patients with resected primary pulmonary sarcomatoid carcinomaTranslational Lung Cancer Research2022-05-31高树庚
11Elevated Heterogeneous Nuclear Ribonucleoprotein C Expression Correlates With Poor Prognosis in Patients With Surgically Resected Lung AdenocarcinomaFrontiers in Oncology2022-05-31高树庚
12Clinicopathological characteristics and prognostic factors of primary pulmonary lymphomaJournal of Thoracic Disease2022-05-31高树庚
13A rare case of primary pulmonary inflammatory pseudotumor-like follicular dendritic cell sarcoma successfully treated by lobectomyAnnals of Translational Medicine2022-05-31高树庚
14Uniportal versus multiportal thoracoscopic sleeve lobectomy for the surgical treatment of centrally located lung cancer: a single institution experienceJournal of Thoracic Disease2022-05-31高树庚
15Construction and validation of a novel immune and tumor mutation burden-based prognostic model in lung adenocarcinomaCancer Immunology Immunotherapy2022-05-31高树庚
16Programmed cell death ligand 1 expression in esophageal squamous cell carcinoma: a comparative analysis of three different assaysChinese Medical Journal2022-05-31高树庚
17Comprehensive Analysis of PD-L1 Expression, Immune Infiltrates, and m6A RNA Methylation Regulators in Esophageal Squamous Cell CarcinomaFrontiers in immunology2022-05-31高树庚
18The value of multidisciplinary team (MDT) management in the diagnosis and treatment of primary intrathoracic synovial sarcomas: a single-center experienceJournal of Thoracic Disease2022-05-31高树庚
19Prognostic value of tumor-infiltrating lymphocytes in esophageal cancer: an updated meta-analysis of 30 studies with 5,122 patientsAnnals of Translational Medicine2022-05-31高树庚
20Neoadjuvant PD-1 inhibitor (Sintilimab) in Non-Small Cell Lung CancerJournal of Thoracic Oncology2022-05-31高树庚
21Lung Cancer in People’s Republic of ChinaJournal of Thoracic Oncology2022-05-31高树庚
22Immune signature of tumor-infiltrating immune cells predicts the prognosis and therapeutic effects in squamous cell carcinomaInternational Immunopharmacology2022-05-31高树庚
23Comprehensive Analysis of Ferroptosis Regulators in Lung Adenocarcinomas Identifies Prognostic and Immunotherapy-Related BiomarkersFrontiers in Molecular Biosciences2022-05-31高树庚
24Three-dimensional reconstruction/personalized three-dimensional printed model for thoracoscopic anatomical partial-lobectomy in stage I lung cancer: a retrospective studyTranslational Lung Cancer Research2022-05-31高树庚
25Bleeding is the most common cause of unplanned return to operating room after lung cancer surgeriesJournal of Thoracic Disease2022-05-31高树庚
26Esophageal Squamous Cell Carcinoma Involving the Lip, Back and HipJournal of Thoracic Oncology2022-05-31高树庚
27Clinicopathologic Correlation With Expression of PD-L1 on Both Tumor Cells and Tumor-infiltrating Immune Cells in Patients With Non–Small Cell Lung CancerJournal of Immunotherapy2022-05-31高树庚
28Clinical significance of ≥ 50% PD-L1 expression with the SP263 monoclonal antibody in non-small cell lung cancer patientsThoracic Cancer2022-05-31高树庚
29Long-term outcomes and prognostic factors of patients with surgically treated pulmonary atypical carcinoid tumors: our institutional experience with 68 patientsJournal of Thoracic Disease2022-05-31高树庚
30Clinical significance of skipping mediastinal lymph node metastasis in N2 non-small cell lung cancerJournal of Thoracic Disease2022-05-31高树庚
31The Society for Translational Medicine: clinical practice guidelines for the postoperative management of chest tube for patients undergoing lobectomyJournal of Thoracic Disease2022-05-31高树庚
32The Society for Translational Medicine: clinical practice guidelines for mechanical ventilation management for patients undergoing lobectomyJournal of Thoracic Disease2022-05-31高树庚
33Pseudogene PHBP1 promotes esophageal squamous cell carcinoma proliferation by increasing its cognate gene PHB expressionOncotarget2022-05-31高树庚
34Unilateral absence of pulmonary artery associated with contralateral lung cancerJournal of Thoracic Disease2022-05-31高树庚
35Systematic Review and Meta-analysis of Atrial Fibrillation Prophylaxis After Lung SurgeryJ Cardiovasc Pharmacol2022-05-31高树庚
36Loss of SUSD2 expression correlates with poor prognosis in patients with surgically resected lung adenocarcinomaJournal of Cancer2022-05-31高树庚
37Elevated SLC2A1 Expression Correlates with Poor Prognosis in Patients with Surgically Resected Lung Adenocarcinoma: A Study Based on Immunohistochemical Analysis and BioinformaticsDNA and Cell Biology2022-05-31高树庚
38Development and validation of an immune‐related prognostic signature in lung adenocarcinomaCancer Medicine2022-05-31高树庚
39Up-regulation of C5orf34 promotes lung adenocarcinoma migration and is correlated with worse prognosisGene2022-05-31高树庚
40The?powered?vascular?staple?(PVS)?versus?conventional?powered?linier?cutter?(PLC) for the?application?of?bronchial?transection?in?thoracoscopic?anatomic?segmentectomyJournal of Thoracic Disease2022-05-31高树庚
41Clinicopathological features and prognosis of ciliated muconodular papillary tumorJournal of Cardiothoracic Surgery2022-05-31高树庚
42Clinical guidelines on perioperative management strategies for enhanced recovery after lung surgeryTranslational?Lung?Cancer?Research2022-05-31高树庚
43The role of maintenance therapy in the treatment of elderly non-small-cell lung cancer patients: a meta-analysis of randomized controlled trialsDrug Design, Development and Therapy2022-05-31高树庚
44Open three-stage transthoracic oesophagectomy versus minimally invasive thoraco-laparoscopic oesophagectomy for oesophageal cancer: protocol for a multicentre prospective, open and parallel, randomised controlled trialBmj Open2022-05-31高树庚
45Expert consensus on perioperative immunotherapy for local advanced non-small cell lung cancerTranslational Lung Cancer Research2022-05-31高树庚
46Identification of prognostic genes and tumor-infiltrating immune cells in the tumor microenvironment of esophageal squamous cell carcinoma and esophageal adenocarcinomaTranslational Cancer Research2022-05-31高树庚
47Prognostic Impact of IGF2BP3 Expression in Patients with Surgically Resected Lung AdenocarcinomaDNA and Cell Biology2022-05-31高树庚
48Uniportal video-assisted thoracic surgery for the treatment of lung cancer: a consensus report from Chinese Society for Thoracic and Cardiovascular Surgery (CSTCVS) and Chinese Association of Thoracic Surgeons (CATS)Translational Lung Cancer Research2022-05-31高树庚
49Translational value of IDH1 and DNA methylation biomarkers in diagnosing lung cancers: a novel diagnostic panel of stage and histology-specificity. Journal of Translational Medicine2022-05-31高树庚
50miR-873 induces lung adenocarcinoma cell proliferation and migration by targeting SRCIN1American Journal of Translational Research2022-05-31高树庚
51PSC subtyping based on TTF-1 and p40 expression reveals distinct molecular characteristics and therapeutic strategiesInternational Journal of Cancer2023-07-02高树庚
52Letter to the Editor: An ultra-sensitive assay using cell-free DNA fragmentomics for multi-cancer early detectionMolecular Cancer2023-07-02高树庚
53A Pan-Cancer Analysis of the Oncogenic Role of WD Repeat Domain 74 in Multiple TumorsFrontiers in Genetics2023-07-02高树庚
54Outcomes and experience of anatomical partial lobectomy The Journal of Thoracic and Cardiovascular Surgery2023-07-02高树庚
55RNA modification writer expression profiles predict clinical outcomes and guide neoadjuvant immunotherapy in non-small cell lung cancerEbioMedicine2023-07-02高树庚
56Integrating microarray-based spatial transcriptomics and single-cell RNA-sequencing reveals tissue architecture in esophageal squamous cell carcinomaEbioMedicine2023-07-02高树庚
57ERAP2 Is Associated With Immune Infiltration and Predicts Favorable Prognosis in SqCLCFrontiers in immunology2023-07-02高树庚
58Global burden and temporal trends in incidence and mortality of oesophageal cancerJournal of advanced research2023-07-02高树庚
59Comprehensive analysis of the immunological implication and prognostic value of CXCR4 in non-small cell lung cancerCancer Immunology Immunotherapy2023-07-02高树庚
60Reporting guidelines for surgical technique could be improved: a scoping review and a call for actionJournal of clinical epidemiology2023-07-02高树庚
61Association between radiotherapy and risk of second primary malignancies in patients with resectable lung cancer: a population-based studyJournal of translational medicine2023-07-02高树庚
62The epidemic of malignant mesothelioma in China: a prediction of incidence during 2016-2030Translational Lung Cancer Research2023-07-02高树庚
63Efficacy, Safety, and Biomarker Analysis of Neoadjuvant Camrelizumab and Apatinib in Patients With Resectable NSCLC: A Phase 2 Clinical TrialJournal of Thoracic Oncology2023-07-02高树庚
64Comparing a PD-L1 inhibitor plus chemotherapy to chemotherapy alone in neoadjuvant therapy for locally advanced ESCC: a randomized Phase II clinical trial : A randomized clinical trial of neoadjuvant therapy for ESCCBMC medicine2023-07-02高树庚
65Multiple primary lung cancer: Updates of clinical management and genomic featuresFrontiers in Oncology2023-07-02高树庚
66Single-cell RNA-sequencing data reveals the genetic source of extracellular vesicles in esophageal squamous cell carcinomaPharmacological Research2023-07-02高树庚
67PVR/TIGIT and PD-L1/PD-1 expression predicts survival and enlightens combined immunotherapy in lung squamous cell carcinomaTranslational Oncology2023-07-02高树庚
68Expert consensus on perioperative treatment for non-small cell lung cancerTranslational Lung Cancer Research2023-07-02高树庚
69Sensitive detection of stage I lung adenocarcinoma using plasma cell-free DNA breakpoint motif profilingEbioMedicine2023-07-02高树庚
70Identification and Validation of a Novel Signature Based on NK Cell Marker Genes to Predict Prognosis and Immunotherapy Response in Lung Adenocarcinoma by Integrated Analysis of Single-Cell and Bulk RNA-SequencingFrontiers in immunology2023-07-02高树庚
71Three-Year Follow-Up of Neoadjuvant Programmed Cell Death Protein-1 Inhibitor (Sintilimab) in NSCLCJournal of Thoracic Oncology2023-07-02高树庚
72A new N descriptor for non-small cell lung cancer: the classification based on anatomic location, number and ratio of metastatic lymph nodesTranslational Lung Cancer Research2023-07-02高树庚
73Efficacy and safety of esophagectomy via left thoracic approach versus via right thoracic approach for middle and lower thoracic esophageal cancer: a multicenter randomized clinical trial (NST1501)Annals of Translational Medicine2023-07-02高树庚
74TIGIT/CD47 dual high expression predicts prognosis and is associated with immunotherapy response in lung squamous cell carcinomaThoracic Cancer2023-07-02高树庚
75Identifying novel tumor-related antigens and immune phenotypes for developing mRNA vaccines in lung adenocarcinomaInternational Immunopharmacology2023-07-02高树庚
76Consolidation Tumor Ratio Combined With Pathological Features Could Predict Status of Lymph Nodes of Early-Stage Lung AdenocarcinomaFrontiers in Oncology2022-05-31高树庚
77Evidence on reporting guidelines for surgical technique in clinical disciplines: a scoping review protocolGland Surgery2022-05-31高树庚
78Lobectomy?vs.?sublobectomy for stage I non-small-cell lung cancer: a meta-analysisAnnals of Translational Medicine2022-05-31高树庚
79Primary pulmonary epithelioid malignant peripheral nerve sheath tumor in a child: a case reportAnnals of Translational Medicine2022-05-31高树庚
80Uniportal video-assisted thoracic surgery could reduce postoperative thorax drainage for lung cancer patientsThoracic Cancer2022-05-31高树庚
81Minimally invasive McKeown esophagectomy with two-field lymph node dissection and manual cervical esophagogastric anastomosis.Journal of Thoracic Disease2022-05-31高树庚
82Effectiveness of crizotinib in a patient with mesenchymal-epithelial transition overexpression/fluorescence in situ hybridization-negative/next-generation sequencing-negative advanced lung adenocarcinoma: a case reportTranslational Cancer Research2022-05-31高树庚
83Concomitant TP53 mutations with response to crizotinib treatment in patients with ALK-rearranged non-small-cell lung cancerCancer Medicine2022-05-31高树庚
84Pan-cancer analysis combined with experiments explores the oncogenic role of spindle apparatus coiled-coil protein 1 (SPDL1)Cancer Cell International2022-05-31高树庚
85Dynamic recurrence risk and adjuvant chemotherapy benefit prediction by ctDNA in resected NSCLCNature Communications2022-05-31高树庚
86Uniportal video‐assisted thoracoscopic left pneumonectomy: Retrospective analysis of eighteen consecutive patients from a single centerThoracic Cancer2022-05-31高树庚
87Elevated TOP2A and UBE2C expressions correlate with poor prognosis in patients with surgically resected lung adenocarcinoma: a study based on immunohistochemical analysis and bioinformaticsJournal of Cancer Research and Clinical Oncology?2022-05-31高树庚
88Development of a predictive nomogram for cause-specific mortality in surgically resected early-stage oesophageal cancer: a Surveillance, Epidemiology, and End Results (SEER) analysisJournal of Thoracic Disease2022-05-31高树庚
89Variation of Programmed Death Ligand 1 Expression After Platinum-based Neoadjuvant Chemotherapy in Lung CancerJournal of Immunotherapy2022-05-31高树庚
90Clinicopathological characteristics and prognosis of lung cancer in young patients aged 30 years and younger Journal of Thoracic Disease2022-05-31高树庚
91Subjecting appropriate lung adenocarcinoma samples to next-generation sequencing-based molecular testing: challenges and possible solutions.Molecular Oncology2022-05-31高树庚
92Research Progress of Anti-PD-1/PD-L1 Immunotherapy Related Mechanisms and Predictive Biomarkers in NSCLCFrontiers in Oncology2022-05-31高树庚
93Comparison of surgical difficulty in patients with resectable non-small cell lung cancer under different neoadjuvant treatment modes: a retrospective cohort studyJournal of Thoracic Disease2022-05-31高树庚
94Identification of prognostic genes in lung adenocarcinoma immune microenvironmentChinese Medical Journal2022-05-31高树庚
95Ultrathin endoscopy versus computed tomography in the detection of anastomotic leak in the early period after esophagectomySurgical Oncology2022-05-31高树庚
96Ten-Year Trends of Clinicopathologic Features and Surgical Treatment of Lung Cancer in ChinaAnnals of Thoracic Sugery2022-05-31高树庚
97Diagnosis, treatment, and prognosis of bronchopulmonary carcinoid: an analysis of 74 patientsAnti-Cancer Drugs2022-05-31高树庚
98Characteristics and Surgical Outcomes for Primary Malignant Melanoma of the EsophagusScientific Reports2022-05-31高树庚
99BRD7 Acts as a Tumor Suppressor Gene in Lung AdenocarcinomaPLoS One2022-05-31高树庚
100A multi-center evaluation of a powered surgical stapler in video-assisted thoracoscopic lung resection procedures in ChinaJournal of Thoracic Disease2022-05-31高树庚
101Robot-assisted thoracic surgery versus open thoracic surgery for lung cancer: a system review and meta-analysisInternational Journal of Clinical and Experimental Medicine2022-05-31高树庚
102Partial?esophagogastrostomy?with?esophagogastric?anastomosis?below?the?aortic?arch?in?cardiac?carcinoma:?characteristics?and?treatment?of?postoperative?anastomotic?leakageJournal of Thoracic Disease2022-05-31高树庚
103Plasma extracellular vesicle microRNA profiling and the identification of a diagnostic signature for stage I lung adenocarcinomaCancer Science2022-05-31高树庚
104Developing the surgical technique reporting checklist and standards: a study protocolGland Surgery2022-05-31高树庚
105The effectiveness of three-dimensional reconstruction in the localization of multiple nodules in lung specimens: a prospective cohort studyTranslational Lung Cancer Research2022-05-31高树庚
106Treatment outcomes of patients with tracheobronchial mucoepidermoid carcinoma compared with those with adenoid cystic carcinomaEuropean Journal of Surgical Oncology2022-05-31高树庚
107Multimodal analysis of cell-free DNA whole-methylome sequencing for cancer detection and localizationNature Communications2024-02通讯作者
108Genomic characteristics and immune landscape of super multiple primary lung cancerEbioMedicine2024-02通讯作者
109Plasma extracellular vesicle long RNAs predict response to neoadjuvant immunotherapy and survival in patients with non-small cell lung cancerPharmacological Research2023-10通讯作者
110Single-cell RNA sequencing analysis reveals transcriptional heterogeneity of multiple primary lung cancerClinical and translational medicine2023-10通讯作者
111Minimal residual disease profiling predicts pathological complete response in esophageal squamous cell carcinomaMolecular Cancer2024-05通讯作者
  • 科研获奖Research Awards
# 获奖证书编号 奖项名称 获奖级别 获奖类别 获奖等级 获奖日期 颁奖单位 本单位是否为第一完成单位 完成单位排名 本人排序 备注
12017011182P1503肺癌个体化微创根治相关技术的系统研究及临床应用推广省部级其他省部级奖励一等奖2017-11-18中国医疗保健国际交流促进会33
22018-J-253-2-02-R04肺癌微创治疗体系及关键技术的研究与推广国家级国家最高科学技术奖、自然科学奖、技术发明奖、科技进步奖二等奖2018-12-12中华人民共和国国务院44
32017011194P1504肺癌个体化微创根治相关技术的系统研究及临床应用推广省部级其他省部级奖励一等奖2018-01-22中华医学会44
  • 研究成果Research Findings
# 成果类型 项目/专利/新品种名称
1作为主创人员获得授权的发明专利和新品种一种锆瓷手术电极
2作为主创人员获得授权的发明专利和新品种用于肺癌诊断的试剂盒、装置及方法
3作为主创人员获得授权的发明专利和新品种一种用于预测肿瘤突变负荷的核酸组合物及其方法和设备
4作为主创人员获得授权的发明专利和新品种外周血甲基化基因及IDH1联合检测诊断肺癌模型
5出版高水平专著胸外科热点问题专家评论
6出版高水平专著应对食管癌专家谈
7出版高水平专著Esophageal Cancer
8出版高水平专著Segmentectomy for Thoracic Diseases