导师风采
毛友生
个人信息
Personal Information
- 性别：男
- 导师类型：博士生导师
- 职称：教授
- 该职称任职时间：2004
联系方式
Contact Information
- 所属院系：肿瘤医院
- 所属专业：肿瘤学
- 邮箱 : youshengmao@gmail.com
- 工作电话 : 010-87788909
个人简介
Personal Profile
毛友生，医学博士，主任医师, 胸外科一病区主任， 博士生导师。 1984年毕业于湘雅医学院到中国医学科学院肿瘤医院胸外科工作至今，现任胸外科胸一病区主任，中国抗癌协会食管癌专业委员会候任主任委员；中国国际食管疾病协会前任主席；中国控烟协会肺癌防治委员会常委，国际食管疾病协会和国际抗癌联盟及国际肺癌研究协会会员；中国肿瘤临床与康复杂志编委；中华医学杂志英文版、中华外科杂志、中华肿瘤杂志等杂志审稿专家。在肺癌、食管癌、贲门癌及纵隔肿瘤等胸部肿瘤诊断和手术治疗方面积累了丰富的临床经验，擅长胸腔镜微创外科治疗肺癌、食管癌和纵膈肿瘤及早期肺癌影像诊断分析。曾赴美国马利兰大学医学院心胸外科进修学习两年。主持和参与多项肺癌和食管癌研究,包括十一五和十二五国家科技支撑计划课题：“非小细胞肺癌规范化多学科综合治疗的多中心协作研究”及“基于网络平台的食管癌规范化综合治疗示范研究”。已在国内外医学杂志上发表文章60余篇。参与编写《胸部肿瘤学》及《临床肿瘤学》两部著作（第一副主编）。
团队简介
Team Profile
待补充更新
- 研究方向Research Directions
肺癌及食管癌临床及转化研究
- 在校研究生Current Graduate Students
硕士研究生 0 名，博士研究生 6 名
- 科研项目Research Projects
| # | 项目名称 | 起止日期 | 金额 | 项目类型 | 本人角色 |
|---|---|---|---|---|---|
| 1 | 不同期别非小细胞肺癌患者围手术期和术后血液 循环肿瘤细胞监测与预后关系的研究 | 2020-10-01 —— 2023-09-01 | 50.0 | 主持在研的国家或省部级科研项目 | 主持者 |
| 2 | 早期非小细胞肺癌患者术后应用胸腺法新免疫相关疗效评估 | 2024-06 —— 2027-06 | 63万 | 主持的企业/行业委托重大项目 | 主持人 |
| 3 | 依据快速人工智能肺动脉流域三维立体成像技术指导解剖性部分肺叶切除术的教学培训效果研究 | 2024-01 —— 2025-12 | 2万 | 主持的企业/行业委托重大项目 | 主持人 |
- 发表论文Papers
| # | 论文题目 | 期刊名称 | 发表年份 | 论文署名 |
|---|---|---|---|---|
| 1 | Long-term survival of the middle and lower thoracic esophageal cancer patients after surgical treatment through left or right thoracic approach | J Thorac Dis | 2022-07-11 | 毛友生 |
| 2 | 食管癌环周切缘阳性对预测食管癌预后的研究现状 | 中华肿瘤杂志 | 2022-07-11 | 毛友生 |
| 3 | Optimal preoperative neoadjuvant therapy for resectable locally advanced esophageal squamous cell carcinoma | Ann N Y Acad Sci | 2022-06-09 | 毛友生 |
| 4 | Ⅰ期非小细胞肺癌预后影响因素的研究进展 | 中国肿瘤 | 2022-06-09 | 毛友生 |
| 5 | Spread through air spaces predicts a worse survival in patients with stage I adenocarcinomas >2 cm after radical lobectomy | J Thorac Dis | 2022-06-09 | 毛友生 |
| 6 | Identification of Tumor Microenvironment-Related Prognostic lncRNAs in Lung Adenocarcinoma | Front Oncol | 2022-06-09 | 毛友生 |
| 7 | A novel nomogram predicting the risk of postoperative pneumonia for esophageal cancer patients after minimally invasive esophagectomy | Surg Endosc | 2022-06-09 | 毛友生 |
| 8 | Comparison of Two Proposed Changes to the Current Nodal Classification for Non-Small Cell Lung Cancer Based on the Number and Ratio of Metastatic Lymph Nodes | Chest | 2022-06-09 | 毛友生 |
| 9 | 胸段食管癌经胸腔镜手术与常规开胸手术淋巴结清扫程度的比较 | 中华肿瘤杂志 | 2022-06-09 | 毛友生 |
| 10 | 肺磨玻璃结节筛查及随诊研究进展 | 中华肿瘤杂志 | 2022-06-09 | 毛友生 |
| 11 | 中国食管癌临床流行特征及外科治疗概况大数据分析 | 中华肿瘤杂志 | 2022-06-09 | 毛友生 |
| 12 | 食管癌手术入路和淋巴结清扫范围的选择 | 中华胃肠外科杂志 | 2022-06-09 | 毛友生 |
| 13 | 我国食管癌外科治疗目前存在的热点争议与未来研究方向 | 中华胃肠外科杂志 | 2022-06-09 | 毛友生 |
| 14 | 胸段食管癌手术入路选择争议与共识 | 中华胃肠外科杂志 | 2022-06-09 | 毛友生 |
| 15 | GINS4 might be a novel prognostic immune-related biomarker of not only esophageal squamous cell carcinoma and other cancers | BMC Med Genomics . | 2022-06-09 | 毛友生 |
| 16 | Mesenchymal cystic hamartoma of the lung: A case report | Medicine (Baltimore) | 2022-06-09 | 毛友生 |
| 17 | Lobe-specific Lymph Node Dissection in Clinical Stage IA Solid-dominant Non-small-cell Lung Cancer: A Propensity Score Matching Study | Clin Lung Cancer | 2022-06-09 | 毛友生 |
| 18 | Analysis of a registry database for esophageal cancer from high-volume centers in China | Dis Esophagus | 2022-06-09 | 毛友生 |
| 19 | 胸部肿瘤外科临床研究的质量控制 | 中国胸心血管外科临床杂志 | 2022-06-09 | 毛友生 |
| 20 | 胸段食管癌喉返神经旁淋巴结转移对食管癌颈部淋巴结清扫的指导价值 | 中华肿瘤杂志 | 2022-06-09 | 毛友生 |
| 21 | YM155, a survivin suppressant, triggers PARP-dependent cell death (parthanatos) and inhibits esophageal squamous-cell carcinoma xenografts in mice. | ONCOTARGET | 2022-06-09 | 毛友生 |
| 22 | 胸段食管鳞癌淋巴结转移规律及淋巴结清扫方式的选择 | 中华胃肠外科杂志 | 2022-07-11 | 毛友生 |
| 23 | 食管肿瘤微创外科治疗进展 | 中华胃肠外科杂志 | 2022-07-11 | 毛友生 |
| 24 | 肺上沟瘤的治疗进展 | 中国肺癌杂志 | 2022-07-11 | 毛友生 |
| 25 | Prognostic factors in curatively resected pathological stage I lung adenocarcinoma. | J Thorac Dis | 2022-06-09 | 毛友生 |
| 26 | Predictors of lymph node metastasis and possible selective lymph node dissection in clinical stage IA non-small cell lung cancer. | J Thorac Dis | 2022-06-09 | 毛友生 |
| 27 | Society for Translational Medicine Expert consensus on the selection of surgical approaches in the management of thoracic esophageal carcinoma | J Thorac Dis | 2022-06-09 | 毛友生 |
| 28 | 病理亚型在Ⅰ期肺腺癌手术方式选择中作用的研究进展 | 中国肿瘤 | 2022-06-09 | 毛友生 |
| 29 | 胸段食管癌喉返神经旁淋巴结清扫的技术要点与相关并发症的防治 | 中华肿瘤杂志 | 2022-06-09 | 毛友生 |
| 30 | 肺癌胸腔镜术后并发症的防治策略 | 中国肺癌杂志 | 2022-06-09 | 毛友生 |
| 31 | Intraoperative frozen section for identifying the invasion status of lung adenocarcinoma: A systematic review and meta-analysis | Int. J. Surg | 2022-06-09 | 毛友生 |
| 32 | The current optimal multimodality treatments for oesophageal squamous-cell carcinoma: A systematic review and meta-analysis | Int. J. Surg | 2022-06-09 | 毛友生 |
| 33 | 可切除非小细胞肺癌新辅助免疫治疗的进展 | 中国肺癌杂志 | 2022-06-09 | 毛友生 |
| 34 | Lymph node dissection and recurrent laryngeal nerve protection in minimally invasive esophagectomy | Ann N Y Acad Sci | 2022-06-09 | 毛友生 |
| 35 | Correlation between CXCR4, CXCR5 and CCR7 expression and survival outcomes in patients with clinical T1N0M0 non-small cell lung cancer | Thorac Cancer | 2022-06-09 | 毛友生 |
| 36 | Elevated expression of lung development-related protein HSP90β indicates poor prognosis in non-small cell lung cancer through affecting the cell cycle and apoptosis | Signal Transduct Target Ther | 2022-06-09 | 毛友生 |
| 37 | 早期非小细胞肺癌淋巴结转移规律与清扫方式研究进展 | 中国肺癌杂志 | 2022-06-09 | 毛友生 |
| 38 | T1期非小细胞肺癌纵膈淋巴结转移规律及清扫方式研究进展 | 中国肺癌杂志 | 2022-06-09 | 毛友生 |
| 39 | Moving forward: the nationwide advertising ban of areca nut in China | Oral Oncol | 2022-06-09 | 毛友生 |
| 40 | Oncologic outcomes of segmentectomy vs lobectomy in pathologic stage IA (≤2 cm) invasive lung adenocarcinoma: A population-based study | J Surg Oncol | 2022-06-09 | 毛友生 |
| 41 | Epidemiology of Lung Cancer | Surg Oncol Clin N Am | 2022-06-09 | 毛友生 |
| 42 | 胸段食管鳞状细胞癌右喉返神经旁淋巴结转移特点 | 中华肿瘤杂志 | 2024-06 | 通讯作者 |
| 43 | Minimally invasive versus open esophagectomy for resectable thoracic esophageal cancer (NST 1502): a multicenter prospective cohort study | Journal of the National Cancer Center | 2023-06 | 第一作者 |
| 44 | Efficacy and safety of esophagectomy via left thoracic approach versus via right thoracic approach for middle and lower thoracic esophageal cancer: a multicenter randomized clinical trial (NST1501) | Ann Transl Med. | 2022-08 | 第一作者 |
| 45 | 中国食管癌研究热点和展望 | 中华胃肠外科杂志 | 2023-06 | 通讯作者 |
| 46 | 食管癌淋巴结转移与预后关系研究进展 | 中华胃肠外科杂志 | 2024-01 | 通讯作者 |
| 47 | 浅表食管癌淋巴结转移的危险因素和预测模型：进展与挑战 | 肿瘤预防与治疗 | 2024-01 | 通讯作者 |
| 48 | 多原发肺癌的诊疗进展 | 癌症进展 | 2023-08 | 通讯作者 |
| 49 | Pathological response and tumor stroma immunogenic features predict long-term survival in non-small cell lung cancer after neoadjuvant chemotherapy | Cell Oncol (Dordr) | 2024-02 | 通讯作者 |
| 50 | Proposed novel grading system for stage I invasive lung adenocarcinoma and a comparison with the 2020 IASLC grading system. | Thorac Cancer | 2024-03 | 通讯作者 |
| 51 | The impact of open access on citations, Pageviews, and downloads: a scientometric analysis in Postgraduate Medical Journal. | Postgrad Med J | 2024-04 | 通讯作者 |
| 52 | Proteome-Wide Multicenter Mendelian Randomization Analysis to Identify Novel Therapeutic Targets for Lung Cancer. | Arch Bronconeumol. | 2024-05 | 通讯作者 |
| 53 | Career adaptability among new oncology nurses: A longitudinal exploration. | Int Nurs Rev. | 2024-05 | 通讯作者 |
| 54 | New perspectives on cancer clinical research in the era of big data and machine learning. | Surg Oncol | 2024-02 | 通讯作者 |
| 55 | Screening microRNAs as potential prognostic biomarkers for lung adenocarcinoma | Ann Med | 2023-02 | 通讯作者 |
| 56 | MARCKSL1 interacted with F-actin to promote esophageal squamous cell carcinoma mobility by modulating the formation of invadopodia. | Cancer Med. | 2023-02 | 通讯作者 |
| 57 | Nomograms for intraoperative prediction of lymph node metastasis in clinical stage IA lung adenocarcinoma. | Cancer Med. | 2023-05 | 通讯作者 |
| 58 | Pan-cancer analysis of TRPV2 identifies its potential role as a prognostic and immunologic biomarker in oesophageal cancer. | Br J Cancer. | 2023-06 | 通讯作者 |
| 59 | Multi-omics analysis unravels the underlying mechanisms of poor prognosis and differential therapeutic responses of solid predominant lung adenocarcinoma. | Front Immunol. | 2023-02 | 通讯作者 |
| 60 | Risk and prognosis of secondary thoracic cancers after radiation therapy for esophageal cancer. | J Gastroenterol Hepatol. | 2023-06 | 通讯作者 |
| 61 | Do open access articles have a citation advantage in Journal of Hepatology? | J Hepatol. | 2023-04 | 通讯作者 |
| 62 | Regulations on e-cigarettes: China is taking action. Pulmonology. | Pulmonology. | 2023-04 | 通讯作者 |
| 63 | The origin of severe hepatitis of unknown aetiology in children: SARS-CoV-2 or adenovirus? | J Hepatol | 2023-01 | 通讯作者 |
| 64 | Comment on "High population burden of Omicron variant (B.1.1.529) is associated with the emergence of severe hepatitis of unknown etiology in children". | Int J Infect Dis. | 2022-09 | 通讯作者 |
| 65 | Effect of histology on the efficacy of immune checkpoint inhibitors in advanced non-small cell lung cancer: A systematic review and meta-analysis. | Front Oncol. | 2022-11 | 通讯作者 |
| 66 | Pan-Cancer Analysis of B4GALNT1 as a Potential Prognostic and Immunological Biomarker. | J Immunol Res. | 2022-07 | 通讯作者 |
- 科研获奖Research Awards
| # | 获奖证书编号 | 奖项名称 | 获奖级别 | 获奖类别 | 获奖等级 | 获奖日期 | 颁奖单位 | 本单位是否为第一完成单位 | 完成单位排名 | 本人排序 | 备注 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | - | 教育部科学技术进步奖 | 国家级 | 教育部高校科研成果奖（科学技术、人文社科） | 一等奖 | 2013-02-01 | 教育部 | 是 | 1 | 14 | |
| 2 | - | 北京市科学技术奖 | 省部级 | 省（市、自治区）政府自然科学奖、技术发明奖 | 一等奖 | 2012-12-12 | 北京市科委 | 是 | 1 | 14 | |
| 3 | - | 中华医学科技奖 | 国家级 | 科技进步奖、哲学社科奖 | 一等奖 | 2012-12-12 | 中华医学会 | 是 | 1 | 14 |
- 研究成果Research Findings
| # | 成果类型 | 项目/专利/新品种名称 |
|---|---|---|
| 1 | 出版高水平专著 | 临床肿瘤学 |
| 2 | 出版高水平专著 | 胸部肿瘤学 |