导师风采
李雷
个人信息
Personal Information
- 性别：男
- 导师类型：硕导
- 职称：主任医师
- 该职称任职时间：4
联系方式
Contact Information
- 所属院系：北京协和医院
- 所属专业：妇产科学
- 邮箱 : lileigh@163.com
- 工作电话 : 010-69156204
个人简介
Personal Profile
李雷，男，中国协和医科大学临床专业毕业，医学博士，主任医师，硕士生导师，中国民主同盟盟员。 1997年入北京大学生命科学学院医学预科，2000年入中国协和医科大学八年制临床专业。2005年毕业，获博士学位。2005年入职中国医学科学院北京协和医院妇产科。 目前就职于中国医学科学院北京协和医院妇产科妇科肿瘤中心，从事妇科肿瘤的临床和科研工作。 目前担任：疑难重症及罕见病全国重点实验室郎景和实验室负责人；《协和医学杂志》编委会青年编委；中国民主同盟中央卫生与健康委员会委员。2018年以来以第一作者或通讯作者发表SCI收录论著60余篇，以及中文核心论著60余篇。主编著作2部（《协和妇科肿瘤笔记 第一辑》，2016年；《子宫腺肌病2017观点》，2017年）
团队简介
Team Profile
负责北京协和医院妇科肿瘤中心妇科三病房的临床工作，以及疑难重症及罕见病全国重点实验室的科研工作。 临床团队包括五位主任医师、两位副主任医师、两位主治医师。 科研团队即中国医学科学院北京协和医院疑难重症及罕见病全国重点实验室成员，包括两位在站博士后，三位科研助理及四位研究生。 李雷团队的临床四原则： 一、追求自身的公正、清明、善良、开放。 二、尽全力调动资源、因地制宜，服务患者，解决病痛。 三、尽全力维护、促进同事和团队的福祉与成长。 四、追求真理和精深的医学艺术。
- 研究方向Research Directions
妇科肿瘤
- 在校研究生Current Graduate Students
硕士研究生 3 名，博士研究生 0 名
- 科研项目Research Projects
| # | 项目名称 | 起止日期 | 金额 | 项目类型 | 本人角色 |
|---|---|---|---|---|---|
| 1 | 北京协和医院中央高水平医院临床科研专项 | 2022-10 —— 2025-09 | 100 | 参与在研的国家或省部级科研项目 | 主持人 |
| 2 | 基于液体活检的单细胞多组学检测技术在宫颈癌和子宫内膜癌中的系统性研究 | 2022-10 —— 2026-09 | 50 | 主持在研的国家或省部级科研项目 | 主持人 |
| 3 | 细胞学DNA甲基化用于宫颈病变筛查的临床试验及多中心研究 | 2021-10 —— 2024-10 | 100 | 主持在研的国家或省部级科研项目 | 主持人 |
| 4 | 卵巢癌表观遗传学标记物的开发和验证 | 2022-07 —— 2024-09 | 50 | 主持的企业/行业委托重大项目 | 主持人 |
- 发表论文Papers
| # | 论文题目 | 期刊名称 | 发表年份 | 论文署名 |
|---|---|---|---|---|
| 1 | Risk of malignancies among asymptomatic postmenopausal women with thickened endometrium: A cohort study | MEDICINE | 2019-02-01 | 通讯作者 |
| 2 | The incidence and predictors of gynecologic malignancies among postmenopausal patients with endometrial fluid collection | ARCH GYNECOL OBSTET | 2019-04-01 | 通讯作者 |
| 3 | The impact of sexual intercourse during pregnancy on obstetric and neonatal outcomes: a cohort study in China | J OBSTET GYNAECOL | 2019-05-01 | 通讯作者 |
| 4 | Comprehensive functional exercises with patient education for the prevention of venous thrombosis after major gynecologic surgery: A randomized controlled study | THROMB RES | 2019-06-01 | 通讯作者 |
| 5 | Comparison of screening strategies for Lynch syndrome in patients with newly diagnosed endometrial cancer: a prospective cohort study in China | Chinese Journal of Cancer | 2019-06-06 | 通讯作者 |
| 6 | Efficacy of different surgical approaches in the clinical and survival outcomes of patients with early-stage cervical cancer: protocol of a phase III multicentre randomised controlled trial in China | BMJ OPEN | 2019-08-01 | 通讯作者 |
| 7 | Ovarian primary primitive neuroectodermal tumor: a review of cases at PUMCH and in the published literature | Orphanet Journal of Rare Diseases | 2019-06-06 | 通讯作者 |
| 8 | The impact of the surgical routes and learning curve of radical hysterectomy on the survival outcomes in stage IB cervical cancer:A retrospective cohort study | International Journal of Surgery | 2019-06-18 | 通讯作者 |
| 9 | The clinicopathological characteristics and survival outcomes of endometrial carcinoma coexisting with or arising in adenomyosis: A pilot study | SCIENTIFIC REPORTS | 2020-04-01 | 通讯作者 |
| 10 | Efficacy of different surgical approaches on survival outcomes in patients with early-stage cervical cancer: protocol for a multicentre longitudinal study in China. | BMJ Open | 2020-08-08 | 通讯作者 |
| 11 | Germline and somatic mutations of multi-gene panel in Chinese patients with epithelial ovarian cancer: a prospective cohort study | JOURNAL OF OVARIAN RESEARCH | 2019-08-01 | 通讯作者 |
| 12 | Laparoscopic vs. Abdominal Radical Hysterectomy for Locally Advanced Cervical Cancer | FRONTIERS IN ONCOLOGY | 2019-11-01 | 通讯作者 |
| 13 | Diagnostic strategies for recurrent cervical cancer: A cohort study | Front Oncol | 2020-12-01 | 通讯作者 |
| 14 | DNA methylation for cervical cancer screening: a training set in China | CLINICAL EPIGENETICS | 2020-06-01 | 通讯作者 |
| 15 | Survival outcomes of Stage IB cervical cancer treated with standard radical hysterectomy | EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY | 2019-10-01 | 通讯作者 |
| 16 | Treatment of symptomatic adenomyosis with the levonorgestrel-releasing intrauterine system | INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS | 2019-09-01 | 通讯作者 |
| 17 | Minimally invasive versus open radical trachelectomy for early stage cervical cancer: protocol for a multicernter randomized controlled trial in China | Trials | 2020-12-01 | 通讯作者 |
| 18 | The Prognosis of Stage IA Mixed Endometrial Carcinoma A Retrospective Cohort Study | AMERICAN JOURNAL OF CLINICAL PATHOLOGY | 2019-11-01 | 通讯作者 |
| 19 | The prognosis of stage IA synchronous endometrial endometrioid and ovarian carcinomas | ARCHIVES OF GYNECOLOGY AND OBSTETRICS | 2019-09-01 | 通讯作者 |
| 20 | The prognostic role of peritoneal cytology in stage IA endometrial endometrioid carcinomas | CURRENT PROBLEMS IN CANCER | 2020-04-01 | 通讯作者 |
| 21 | Pathological findings following risk-reducing salpingo-oophorectomy in BRCA mutation carriers: A systematic review and meta-analysis | EJSO-EUR J SURG ONC | 2020-01-01 | 通讯作者 |
| 22 | oncologic and obstetric outcomes after conization for adenocarcinoma in situ or stage IA1 cervical cancer | SCI Rep | 2020-11-01 | 通讯作者 |
| 23 | The effects of different instruments and suture methods of conization for cervical lesions | SCIENTIFIC REPORTS | 2019-12-01 | 通讯作者 |
| 24 | Malignant transformation of vaginal adenosis to clear cell carcinoma without prenatal diethylstilbestrol exposure: a case report and literature review | BMC CANCER | 2019-08-13 | 通讯作者 |
| 25 | Successful management of nongestational ovarian choriocarcinoma complicated with choriocarcinoma syndrome: A case report and a literature review | CURRENT PROBLEMS IN CANCER | 2020-08-01 | 通讯作者 |
| 26 | A family pedigree of malignancies associated with BRCA1 pathogenic variants: a reflection of the state of art in China | HEREDITARY CANCER IN CLINICAL PRACTICE | 2019-09-01 | 通讯作者 |
| 27 | Secondary Parkinson disease caused by breast cancer during pregnancy: A case report | WORLD JOURNAL OF CLINICAL CASES | 2019-12-01 | 通讯作者 |
| 28 | Pathologically confirmed brain metastases from primary uterine cervical tumors: two cases and a literature review | WORLD JOURNAL OF SURGICAL ONCOLOGY | 2019-10-01 | 通讯作者 |
| 29 | The Urodynamics and Survival Outcomes of Different Methods of Dissecting the Inferior Hypogastric Plexus in Laparoscopic Nerve-Sparing Radical Hysterectomy of Type C: A Randomized Controlled Study | ANN SURG ONCOL | 2019-05-01 | 第一作者 |
| 30 | Treatment of symptomatic adenomyosis with the levonorgestrel-releasing intrauterine system | INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS | 2019-09-01 | 第一作者 |
| 31 | The prophylactic effects of long-acting granulocyte colony-stimulating factor for febrile neutropenia in newly diagnosed patients with epithelial ovarian cancer: a randomised controlled study | BMJ SUPPORTIVE & PALLIATIVE CARE | 2019-12-01 | 第一作者 |
| 32 | HRD effects on first-line adjuvant chemotherapy and PARPi maintenance therapy in Chinese ovarian cancer patients | npj Precision Oncology | 2023-05-31 | 第一作者 |
| 33 | Secondary Parkinson disease caused by breast cancer during pregnancy: A case report | WORLD JOURNAL OF CLINICAL CASES | 2019-12-01 | 第一作者 |
| 34 | Identifying Serum Small Extracellular Vesicle MicroRNA as a Noninvasive Diagnostic and Prognostic Biomarker for Ovarian Cancer | ACS Nano | 2023-10-10 | 第一作者 |
- 科研获奖Research Awards
无
- 研究成果Research Findings
| # | 成果类型 | 项目/专利/新品种名称 |
|---|---|---|
| 1 | 出版高水平专著 | 协和妇科肿瘤笔记（第一辑） |
| 2 | 出版高水平专著 | 子宫腺肌病2017观点 |