导师风采
戴梦华
个人信息
Personal Information
- 性别：男
- 导师类型：博导
- 职称：主任医师
- 该职称任职时间：2010
联系方式
Contact Information
- 所属院系：北京协和医院
- 所属专业：外科学
- 邮箱 : daim66@126.com
- 工作电话 : 13910307115
个人简介
Personal Profile
戴梦华教授，医学博士，毕业于中国协和医科大学。美国Memorial Sloan-Kettering Cancer Center高级访问学者。长期从事胰腺癌早期诊断和综合治疗的基础及临床研究工作。临床工作方面，每年诊治疑难病症近千例，擅长胆胰疾病的微创手术治疗。近年以第一作者或通讯作者身份发表SCI及中文核心论著30余篇，累计影响因子≥110分.现任中华医学会外科分会内镜及腹腔镜学组委员，北京市医师协会普外科专家委员会委员兼秘书，中国研究型医院学会微创外科分会常务委员，中国医促会胰腺疾病委员会副主任委员。《中国实用外科杂志》、《中华腔镜外科杂志》电子版）和《腹腔镜外科杂志》 编委; 《中华外科杂志》通讯编委，美国《Medicine》编审，《Clinics in Surgery - General Surgery》编委等 。
团队简介
Team Profile
戴梦华教授团队长期从事胰腺癌早期诊断和综合治疗的基础及临床研究工作。临床工作方面，每年诊治疑难病症近千例，擅长胆胰疾病的微创手术治疗，完成根治性胰十二指肠切除术、胰体尾脾切除术和胰岛素瘤切除术百余例，胃癌根治术数百余例，腹膜后肿物切除术近百例。率先在国内开展机器人及腹腔镜微创胰腺外科手术，腹腔镜胰岛素瘤切除术、腹腔镜胰十二指肠切除术、胰腺远端切除术、慢性胰腺炎胰管-空肠侧侧吻合术、胰腺假性囊肿-空肠Roux-en-Y吻合术、腹腔镜腹腔神经丛阻滞术、腹腔镜胃癌根治术和单孔腹腔镜胆囊切除术及阑尾切除术。参与国家九五攻关、国家973攻关课题和十一五科技支撑课题的研究。研究方向：胰腺癌早期诊断及综合治疗。已结题课题：溶瘤单纯疱疹病毒联合放疗治疗胰腺癌协同作用机制的蛋白质组学研究（2010年国家自然基金81071898）、胰腺癌发生发展的蛋白质组学研究（医科院协同创新团队课题）、ERAS理念下胰十二指肠切除术后腹腔引流管拔管时间的多中心RCT研究（北京市科技计划课题首都特色项目Z171100001017018）等。在研课题：1. Tp53-Fas通路在胰腺癌侵袭、转移中的作用与分子机制（2020年国家自然基金面上项目）；2、经腹腔镜及开腹根治性顺行模块胰体尾脾切除术治疗胰体尾癌疗效的多中心随机对照研究（首都卫生发展科研专项2020-1-4011）。
- 研究方向Research Directions
胰腺癌早期诊断及综合治疗
- 在校研究生Current Graduate Students
硕士研究生 1 名，博士研究生 4 名
- 科研项目Research Projects
| # | 项目名称 | 起止日期 | 金额 | 项目类型 | 本人角色 |
|---|---|---|---|---|---|
| 1 | 医科院创新团队-胰腺癌发生发展的蛋白质组学研究 | 2016-09-01 —— 2020-12-31 | 主持的企业/行业委托重大项目 | 主持人 | |
| 2 | 首都特色—ERAS理念下优化胰十二指肠切除术后引流管管理路径的多中心RCT研究 | 2017-02-01 —— 2020-05-01 | 主持在研的国家或省部级科研项目 | 主持人 | |
| 3 | 经腹腔镜及开腹根治性顺行模块胰体尾脾切除术治疗胰体尾癌疗效的多中心随机对照研究 | 2020-07-01 —— 2023-06-01 | 主持在研的国家或省部级科研项目 | 主持人 | |
| 4 | ERAS理念下优化胰十二指肠切除术后引流管管理路径的多中心RCT研究 | 2017-01-07 —— 2020-11-30 | 主持在研的国家或省部级科研项目 | 主持人 | |
| 5 | 首发-经腹腔镜及开腹根治性顺行模块胰体尾脾切除术治疗胰体尾癌疗效的多中心随机对照研究 | 2020-07-01 —— 2023-06-30 | 91 | 主持在研的国家或省部级科研项目 | 主持人 |
| 6 | 十三五课题-胰腺癌转移的新型阶段化分子特征谱及其机制研究 | 2018-01-01 —— 2020-12-31 | 主持在研的国家或省部级科研项目 | 主持人 | |
| 7 | TP53-FAS信号通路介导胰腺癌预后的基因组测序及分子机制研究 | 2021-01-01 —— 2024-12-31 | 57万 | 主持在研的国家或省部级科研项目 | 主持人 |
| 8 | 胰腺癌多学科协作精准诊疗体系 | 2022-06 —— 2025-06 | 120万 | 参与在研的国家或省部级科研项目 | 参与者 |
| 9 | 胰腺囊性肿瘤的综合诊治研究 | 2022-11 —— 2025-11 | 105万 | 参与在研的国家或省部级科研项目 | 参与者 |
- 发表论文Papers
| # | 论文题目 | 期刊名称 | 发表年份 | 论文署名 |
|---|---|---|---|---|
| 1 | Effect of Blumgart anastomosis in reducing the incidence rate of pancreatic fistula after pancreatoduodenectomy. | WORLD JOURNAL OF GASTROENTEROLOGY | 2019-05-28 | 通讯作者 |
| 2 | Risk factors for new-onset diabetes mellitus after distal pancreatectomy | BMJ OPEN DIABETES RESEARCH ＆ CARE | 2020-10-01 | 通讯作者 |
| 3 | High Expression of MUC15 Is Correlated with Poor Prognosis of Pancreatic Cancer and Promotes Migration, Invasion, and Chemo-Resistance In Vitro | MEDICAL SCIENCE MONITOR | 2020-10-01 | 通讯作者 |
| 4 | Glutathione S-Transferase Mu-3 Predicts a Better Prognosis and Inhibits Malignant Behavior and Glycolysis in Pancreatic Cancer | FRONTIERS IN ONCOLOGY | 2020-08-01 | 通讯作者 |
| 5 | Status and situation of postgraduate medical students in China under the influence of COVID-19 | POSTGRADUATE MEDICAL JOURNAL | 2020-05-13 | 通讯作者 |
| 6 | CTC phenotyping for a preoperative assessment of tumor metastasis and overall survival of pancreatic ductal adenocarcinoma patients | EBIOMEDICINE | 2019-08-01 | 通讯作者 |
| 7 | Comparison of minimal invasive versus open radical antegrade modular pancreatosplenectomy (RAMPS) for pancreatic ductal adenocarcinoma: a single center retrospective study | SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES | 2020-10-08 | 通讯作者 |
| 8 | ROBO2 hampers malignant biological behavior and predicts a better prognosis in pancreatic adenocarcinoma | SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY | 2021-06-19 | 通讯作者 |
| 9 | Retrospective analysis of seven cases of pancreatic mixed adenoneuroendocrine carcinoma from a high-volume center and review of the literature | BMC SURGERY | 2019-07-01 | 通讯作者 |
| 10 | Development of a nomogram to predict disease-specific survival for patients after resection of a non-metastatic adenocarcinoma of the pancreatic body and tail | Frontiers in oncology | 2020-10-01 | 通讯作者 |
| 11 | Risk factor for new-onset diabetes mellitus after distal pancreatectomy | BMJ Open Diabetes Res Care | 2020-09-01 | 通讯作者 |
| 12 | Radical antegrade modular pancreatosplenectomy (RAMPS) versus conventional distal pancreatosplenectomy (CDPS) for left-sided pancreatic ductal adenocarcinoma | SURGERY TODAY | 2021-01-03 | 通讯作者 |
| 13 | CD44+Circulating Tumor Endothelial Cells Indicate Poor Prognosis in Pancreatic Ductal Adenocarcinoma After Radical Surgery: A Pilot Study | Cancer Management and Research | 2021-06-01 | 通讯作者 |
| 14 | Changes in Serum Lactate Level Predict Postoperative Intra-Abdominal Infection After Pancreatic Resection | WORLD JOURNAL OF SURGERY | 2021-02-18 | 通讯作者 |
| 15 | Quantitative assessment of the diagnostic role of mucin family members in pancreatic cancer: a meta-analysis | Annals of Translational Medicine | 2021-02-01 | 通讯作者 |
| 16 | Multi-omics analysis of intra-tumoural and inter-tumoural heterogeneity in pancreatic ductal adenocarcinoma | CLINICAL AND TRANSLATIONAL MEDICINE | 2022-01-12 | 通讯作者 |
| 17 | Early Drain Removal is Safe in Patients With Low or Intermediate Risk of Pancreatic Fistula After Pancreaticoduodenectomy A Multicenter, Randomized Controlled Trial | ANNALS OF SURGERY | 2022-02-01 | 通讯作者 |
| 18 | Data mining-based study of collagen type III alpha 1(COL3A1) prognostic value and immune exploration in pan-cancer | Bioengineered | 2021-07-12 | 通讯作者 |
| 19 | Noninvasive detection of pancreatic ductal adenocarcinoma using the methylation signature of circulating tumour DNA | BMC Medicine | 2022-09-25 | 通讯作者 |
| 20 | CD177 Inhibits Neutrophil Extracellular Trap Formation and Protects against Acute Pancreatitis in Mice | Journal of Clinical Medicine | 2023-03-27 | 通讯作者 |
| 21 | Identifying the preoperative factors predicting the surgical difficulty of robotic distal pancreatectomy | SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES | 2023-01-23 | 通讯作者 |
| 22 | Pancreatic stellate cells exploit Wnt/β-catenin/TCF7-mediated glutamine metabolism to promote pancreatic cancer cells growth | CANCER LETTERS | 2023-02-28 | 通讯作者 |
| 23 | Pancreatic ductal adenocarcinoma with synchronous and metachronous hepatic metastasis predicted by contrast- enhanced ultrasound | QUANTITATIVE IMAGING IN MEDICINE AND SURGERY | 2023-06-01 | 通讯作者 |
| 24 | Robotic versus laparoscopic distal pancreatectomy on perioperative outcomes: a systematic review and meta-analysis | Updates in Surgery | 2023-01-01 | 通讯作者 |
| 25 | GSTM3 Function and Polymorphism in Cancer：Emerging but Promising | Cancer Management and Research | 2020-10-01 | 通讯作者 |
| 26 | pancreatic cancer with ovarian metastases: a case report and review of the literature | WORLD JOURNAL OF CLINICAL CASES | 2020-11-01 | 通讯作者 |
| 27 | Mucins in pancreatic cancer: A well-established but promising family for diagnosis, prognosis and therapy | Journal of Cellular & Molecular Medicine | 2020-08-01 | 通讯作者 |
| 28 | Tumor microenvironment in chemoresistance, metastasis and immunotherapy of pancreatic cancer | American Journal of Cancer Research | 2020-07-01 | 通讯作者 |
| 29 | Research Progress on Slit/Robo Pathway in Pancreatic Cancer: Emerging and Promising | JOURNAL OF ONCOLOGY | 2020-06-01 | 通讯作者 |
| 30 | Risk stratification of clinically relevant delayed gastric emptying after pancreaticoduodenectomy | BMC Surgery | 2023-08-09 | 通讯作者 |
| 31 | A novel clinical model for risk prediction and stratification of new- onset diabetes mellitus after distal pancreatectomy | Hepatobiliary Surgery and Nutrition | 2023-12-01 | 通讯作者 |
| 32 | Pancreatic schwannoma mimicking pancreatic cystadenoma: A case report and literature review of the imaging features | MEDICINE | 2019-06-01 | 通讯作者 |
| 33 | Risk factors for new-onset diabetes mellitus after distal pancreatectomy | BMJ OPEN DIABETES RESEARCH ＆ CARE | 2020-10-01 | 第一作者 |
| 34 | Risk factor for new-onset diabetes mellitus after distal pancreatectomy | BMJ Open Diabetes Res Care | 2020-09-01 | 第一作者 |
| 35 | Radical antegrade modular pancreatosplenectomy (RAMPS) versus conventional distal pancreatosplenectomy (CDPS) for left-sided pancreatic ductal adenocarcinoma | SURGERY TODAY | 2021-01-03 | 第一作者 |
| 36 | Early Drain Removal is Safe in Patients With Low or Intermediate Risk of Pancreatic Fistula After Pancreaticoduodenectomy A Multicenter, Randomized Controlled Trial | ANNALS OF SURGERY | 2022-02-01 | 第一作者 |
| 37 | Long-term survival, quality of life, and molecular features of the patients with solid pseudopapillary neoplasm of the pancreas: a retrospective study of 454 cases | ANNALS OF MEDICINE | 2023-12-01 | 第一作者 |
| 38 | Local resection for solid pseudopapillary neoplasms of the pancreas shows improved postoperative gastrointestinal function and reduced mental stress: a multiquestionnaire survey from a large cohort | International Journal of Surgery | 2023-12-01 | 第一作者 |
| 39 | Analysing the causal relationship between potentially protective and risk factors and cutaneous melanoma: A Mendelian randomization study | JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY | 2023-10-04 | 通讯作者 |
- 科研获奖Research Awards
| # | 获奖证书编号 | 奖项名称 | 获奖级别 | 获奖类别 | 获奖等级 | 获奖日期 | 颁奖单位 | 本单位是否为第一完成单位 | 完成单位排名 | 本人排序 | 备注 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2015-254 | 国家科学技术进步奖 | 国家级 | 科技进步奖、哲学社科奖 | 二等奖 | 2016-06-01 | 未知 | 4 | 4 | ||
| 2 | 201502030P1004 | 中华医学科技奖 | 国家级 | 国家最高科学技术奖、自然科学奖、技术发明奖、科技进步奖 | 二等奖 | 2015-06-01 | 未知 | 1 | 1 | 排名无 | |
| 3 | 2015-医-005-04 | 北京市科学技术奖 | 省部级 | 省（市、自治区）政府自然科学奖、技术发明奖 | 一等奖 | 2015-06-01 | 未知 | 1 | 1 | 排名无 |
- 研究成果Research Findings
| # | 成果类型 | 项目/专利/新品种名称 |
|---|---|---|
| 1 | 获得省部级及以上科研奖励 | 胰腺肿瘤影像特征机制研究与技术创新应用 |
| 2 | 作为主创人员获得授权的发明专利和新品种 | 一种基于多组学整合分析的多囊卵巢综合征靶点的筛选方法及多囊卵巢综 |
| 3 | 作为主创人员获得授权的发明专利和新品种 | 器械定位方法、装置、计算机设备和存储介质 |