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个人简介
Personal Profile
2000年毕业于中国协和医科大学临床医学专业,获得博士学位。同年进入北京协和医院内科担任住院医师,2020年起担任主任医师。工作以来作为第一作者或通讯作者在国内核心杂志或国外杂志发表文章100余篇,所著论文2次获得中华风湿病学杂志优秀论文奖。作为主编编辑出版了风湿免疫科疑难病诊断(第2集)。担任了中华临床免疫和变态反应杂志编辑部副主任。参与的系统性红斑狼疮发病机制及诊断方法学研究,获得中华医学科技奖贰等奖(第10位)及高校科技进步奖贰等奖(第12位)。从2008年开始加入了欧洲抗风湿病联盟硬皮病试验研究组队列研究(EUSTAR),并先后两次到国外参加了EUSTAR的系统性硬化症及甲褶微循环培训课程。分别在2011年及2012年申请北京协和医院及中华医学会临床医学科研专项资金——风湿病学发展与研究资金,参与了十一五、十三五和十四五国家重点研究项目。目前研究方向主要在系统性硬化症及干燥综合征的临床和基础方面,建立了前瞻性临床队列、影像学队列和标本库。担任了国家皮肤与免疫疾病临床医学中心硬皮病与肌炎委员会副组长,中国医师学会风湿免疫科分会痛风专业委员会副组长。
团队简介
Team Profile
依托于科室,建立了多种自身免疫性疾病(尤其是系统性硬化症和干燥综合征)前瞻性队列和标本库。与清华大学合作,建立了系统性硬化症前瞻性磁共振影像学队列。基于这些队列和标本库,与北京大学、协和医院临研中心合作,进行基础研究,寻找疾病发病机制。
硕士研究生 2 名,博士研究生 0 名
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# | 论文题目 | 期刊名称 | 发表年份 | 论文署名 |
---|---|---|---|---|
1 | 不同性别系统性硬化症患者的临床特点分析 | 中华内科杂志 | 2022-06-01 | 徐东 |
2 | 系统性红斑狼疮伴Libman-Sacks心内膜炎的临床特点分析 | 中华风湿病学杂志 | 2022-06-01 | 徐东 |
3 | 发病年龄对系统性硬化病临床表现的影响 | 中华风湿病学杂志 | 2022-06-01 | 徐东 |
4 | Gastrointestinal manifestations on impaired quality of life in systemic sclerosis | J Dig Dis | 2019-04-02 | 第一作者 |
5 | Characteristics of Chinese patients with primary Sjogren's syndrome: preliminary report of a multi-centre registration study | LUPUS | 2020-01-01 | 第一作者 |
6 | Association between comorbidities and extraglandular manifestations in primary Sjögren’s syndrome: a multicenter cross-sectional study | Clin Rheumatol | 2020-03-01 | 通讯作者 |
7 | The Chinese herb Tripterygium wilfordii Hook F for the treatment of systemic sclerosis-associated interstitial lung disease: data from a Chinese EUSTAR Center | CLINICAL RHEUMATOLOGY | 2020-03-01 | 通讯作者 |
8 | Clinical features and long-term outcomes of Chinese patients with scleroderma renal crisis | Internatoional Journal of Rheumatic Diseases | 2020-09-01 | 通讯作者 |
9 | Factors Associated With Renal Involvement in Primary Sjogren's Syndrome: A Meta-Analysis | Frontiers in medicine | 2020-11-01 | 第一作者 |
10 | Risk and prognosis factors for systemic sclerosis with lung cancer: A single-centre case-control study in China | INTERNATIONAL JOURNAL OF CLINICAL PRACTICE | 2021-04-01 | 通讯作者 |
11 | Tofacitinib as a possible treatment for skin thickening in diffuse cutaneous systemic sclerosis | RHEUMATOLOGY | 2021-05-14 | 第一作者 |
12 | Characteristics and outcomes of coronary artery involvement in polyarteritis nodosa. | CANADIAN JOURNAL OF CARDIOLOGY | 2021-06-01 | 通讯作者 |
13 | Rheumatic Immune-Related Adverse Events Induced by Immune Checkpoint Inhibitors | Asia-Pacific Journal of Clinical Oncology | 2021-06-01 | 通讯作者 |
14 | Prevalence and risk factors for left ventricular diastolic dysfunction in systemic sclerosis: a multi-center study of CRDC cohort in China | CLIN RHEUMATOL | 2021-11-01 | 通讯作者 |
15 | Primary Sjogren's syndrome is associated with increased risk of malignancies besides lymphoma: A systematic review and meta-analysis. | Autoimmunity reviews | 2022-05-01 | 通讯作者 |
16 | Renal tubular acidosis and associated factors in patients with primary Sjogren’s syndrome: a registry‐based study | CLINICAL RHEUMATOLOGY | 2022-11-16 | 通讯作者 |
17 | Hyperglobulinemia predicts increased risk of mortality in primary Sjögren's syndrome: based on a Chinese multicentre registry | MOD RHEUMATOL. | 2023-01-23 | 通讯作者 |
18 | Identifying risk and prognostic factors in polyarteritis nodosa patients with digital gangrene. | International Journal of Rheumatic Diseases | 2023-02-01 | 通讯作者 |
19 | The clinical characteristics and outcomes of patients with systemic sclerosis with myocardial involvement | Orphanet Journal of Rare Diseases | 2023-04-14 | 通讯作者 |
20 | Predictive value of bone marrow megakaryocyte count for immunotherapeutic response in primary Sjögren's syndrome patients with severe immune thrombocytopenia: A single-center case-control study in China | INT J RHEUM DIS | 2023-07-01 | 通讯作者 |
21 | Efficacy and safety of telitacicept in primary Sjögren's syndrome: a randomized, double-blind, placebo-controlled, phase 2 trial. | RHEUMATOLOGY | 2023-07-03 | 第一作者 |
22 | Diffusing capacity of lungs for carbon monoxide associated with subclinical myocardial impairment in systemic sclerosis: A cardiac MR study | RMD Open | 2023-12-07 | 通讯作者 |
23 | New investigational drugs to treat Sjogren's syndrome: lessons learnt from immunology. | EXPERT OPIN DRUG SAF | 2024-01-31 | 第一作者 |
24 | Systemic sclerosis patients with negative antinuclear antibodies have distinctive clinical manifestations: a multicenter CRDC cohort in China | ZEITSCHRIFT FUR RHEUMATOLOGIE | 2024-02-01 | 通讯作者 |
25 | Digital gangrene in systemic sclerosis patients: not only due to the microvascular disease. | CLIN RHEUMATOL | 2024-02-02 | 通讯作者 |
26 | Prediction of progressive fibrosing interstitial lung disease in patients with systemic sclerosis: insight from the CRDC cohort study | RMD Open | 2024-03-06 | 通讯作者 |
27 | Characterization of kidneys in patients with systemic sclerosis by multi-parametric magnetic resonance quantitative imaging. | J MAGN RESON IMAGING | 2024-03-19 | 通讯作者 |
28 | Telitacicept in patients with active systemic lupus erythematosus: results of a phase 2b, randomised, double-blind, placebo-controlled trial | ANNALS OF THE RHEUMATIC DISEASES | 2024-04-01 | 第一作者 |
29 | Changes of cerebral structure and perfusion in subtypes of systemic sclerosis: a brain magnetic resonance imaging study | rheumatology | 2024-08 | 通讯作者 |
# | 获奖证书编号 | 奖项名称 | 获奖级别 | 获奖类别 | 获奖等级 | 获奖日期 | 颁奖单位 | 本单位是否为第一完成单位 | 完成单位排名 | 本人排序 | 备注 |
---|---|---|---|---|---|---|---|---|---|---|---|
1 | 2009-257 | 系统性红斑狼疮发病机制及诊断方法学研究 | 省部级 | 科学技术进步奖 | 二等奖 | 2010-01-01 | 教育部 | 是 | 1 | 12 | |
2 | 20090202020P1010 | 系统性红斑狼疮发病机制及诊断方法学研究 | 省部级 | 中华医学科技奖 | 二等奖 | 2009-12-25 | 中华医学会 | 是 | 1 | 10 |
# | 成果类型 | 项目/专利/新品种名称 |
---|---|---|
1 | 出版高水平专著 | 北京协和医院 风湿免疫科疑难病诊断——协和医生临床思维例释 |
2 | 出版高水平专著 | 临床路径释义 |
3 | 出版高水平专著 | 风湿科主治医生1088问 |
4 | 出版高水平专著 | 内科学(第2版) |