导师风采
徐东

个人信息

Personal Information

  • 性别:女
  • 导师类型:硕导
  • 职称:主任医师
  • 该职称任职时间:2020

联系方式

Contact Information

  • 所属院系:北京协和医院
  • 所属专业:内科学
  • 邮箱 : xudong74@hotmail.com
  • 工作电话 : 13621318151

个人简介

Personal Profile

2000年毕业于中国协和医科大学临床医学专业,获得博士学位。同年进入北京协和医院内科担任住院医师,2020年起担任主任医师。工作以来作为第一作者或通讯作者在国内核心杂志或国外杂志发表文章100余篇,所著论文2次获得中华风湿病学杂志优秀论文奖。作为主编编辑出版了风湿免疫科疑难病诊断(第2集)。担任了中华临床免疫和变态反应杂志编辑部副主任。参与的系统性红斑狼疮发病机制及诊断方法学研究,获得中华医学科技奖贰等奖(第10位)及高校科技进步奖贰等奖(第12位)。从2008年开始加入了欧洲抗风湿病联盟硬皮病试验研究组队列研究(EUSTAR),并先后两次到国外参加了EUSTAR的系统性硬化症及甲褶微循环培训课程。分别在2011年及2012年申请北京协和医院及中华医学会临床医学科研专项资金——风湿病学发展与研究资金,参与了十一五、十三五和十四五国家重点研究项目。目前研究方向主要在系统性硬化症及干燥综合征的临床和基础方面,建立了前瞻性临床队列、影像学队列和标本库。担任了国家皮肤与免疫疾病临床医学中心硬皮病与肌炎委员会副组长,中国医师学会风湿免疫科分会痛风专业委员会副组长。

团队简介

Team Profile

依托于科室,建立了多种自身免疫性疾病(尤其是系统性硬化症和干燥综合征)前瞻性队列和标本库。与清华大学合作,建立了系统性硬化症前瞻性磁共振影像学队列。基于这些队列和标本库,与北京大学、协和医院临研中心合作,进行基础研究,寻找疾病发病机制。

  • 研究方向Research Directions
风湿免疫性疾病脏器受累的早期预警
  • 在校研究生Current Graduate Students

硕士研究生 2 名,博士研究生 0 名

  • 科研项目Research Projects


  • 发表论文Papers
# 论文题目 期刊名称 发表年份 论文署名
1不同性别系统性硬化症患者的临床特点分析中华内科杂志2022-06-01徐东
2系统性红斑狼疮伴Libman-Sacks心内膜炎的临床特点分析中华风湿病学杂志2022-06-01徐东
3发病年龄对系统性硬化病临床表现的影响中华风湿病学杂志2022-06-01徐东
4Gastrointestinal manifestations on impaired quality of life in systemic sclerosisJ Dig Dis2019-04-02第一作者
5Characteristics of Chinese patients with primary Sjogren's syndrome: preliminary report of a multi-centre registration studyLUPUS2020-01-01第一作者
6Association between comorbidities and extraglandular manifestations in primary Sjögren’s syndrome: a multicenter cross-sectional studyClin Rheumatol2020-03-01通讯作者
7The Chinese herb Tripterygium wilfordii Hook F for the treatment of systemic sclerosis-associated interstitial lung disease: data from a Chinese EUSTAR CenterCLINICAL RHEUMATOLOGY2020-03-01通讯作者
8Clinical features and long-term outcomes of Chinese patients with scleroderma renal crisisInternatoional Journal of Rheumatic Diseases2020-09-01通讯作者
9Factors Associated With Renal Involvement in Primary Sjogren's Syndrome: A Meta-AnalysisFrontiers in medicine2020-11-01第一作者
10Risk and prognosis factors for systemic sclerosis with lung cancer: A single-centre case-control study in ChinaINTERNATIONAL JOURNAL OF CLINICAL PRACTICE2021-04-01通讯作者
11Tofacitinib as a possible treatment for skin thickening in diffuse cutaneous systemic sclerosisRHEUMATOLOGY2021-05-14第一作者
12Characteristics and outcomes of coronary artery involvement in polyarteritis nodosa.CANADIAN JOURNAL OF CARDIOLOGY2021-06-01通讯作者
13Rheumatic Immune-Related Adverse Events Induced by Immune Checkpoint InhibitorsAsia-Pacific Journal of Clinical Oncology2021-06-01通讯作者
14Prevalence and risk factors for left ventricular diastolic dysfunction in systemic sclerosis: a multi-center study of CRDC cohort in ChinaCLIN RHEUMATOL2021-11-01通讯作者
15Primary Sjogren's syndrome is associated with increased risk of malignancies besides lymphoma: A systematic review and meta-analysis.Autoimmunity reviews2022-05-01通讯作者
16Renal tubular acidosis and associated factors in patients with primary Sjogren’s syndrome: a registry‐based studyCLINICAL RHEUMATOLOGY2022-11-16通讯作者
17Hyperglobulinemia predicts increased risk of mortality in primary Sjögren's syndrome: based on a Chinese multicentre registryMOD RHEUMATOL.2023-01-23通讯作者
18Identifying risk and prognostic factors in polyarteritis nodosa patients with digital gangrene.International Journal of Rheumatic Diseases2023-02-01通讯作者
19The clinical characteristics and outcomes of patients with systemic sclerosis with myocardial involvementOrphanet Journal of Rare Diseases2023-04-14通讯作者
20Predictive value of bone marrow megakaryocyte count for immunotherapeutic response in primary Sjögren's syndrome patients with severe immune thrombocytopenia: A single-center case-control study in ChinaINT J RHEUM DIS2023-07-01通讯作者
21Efficacy and safety of telitacicept in primary Sjögren's syndrome: a randomized, double-blind, placebo-controlled, phase 2 trial. RHEUMATOLOGY2023-07-03第一作者
22Diffusing capacity of lungs for carbon monoxide associated with subclinical myocardial impairment in systemic sclerosis: A cardiac MR studyRMD Open2023-12-07通讯作者
23New investigational drugs to treat Sjogren's syndrome: lessons learnt from immunology.EXPERT OPIN DRUG SAF2024-01-31第一作者
24Systemic sclerosis patients with negative antinuclear antibodies have distinctive clinical manifestations: a multicenter CRDC cohort in ChinaZEITSCHRIFT FUR RHEUMATOLOGIE2024-02-01通讯作者
25Digital gangrene in systemic sclerosis patients: not only due to the microvascular disease.CLIN RHEUMATOL2024-02-02通讯作者
26Prediction of progressive fibrosing interstitial lung disease in patients with systemic sclerosis: insight from the CRDC cohort studyRMD Open2024-03-06通讯作者
27Characterization of kidneys in patients with systemic sclerosis by multi-parametric magnetic resonance quantitative imaging.J MAGN RESON IMAGING2024-03-19通讯作者
28Telitacicept in patients with active systemic lupus erythematosus: results of a phase 2b, randomised, double-blind, placebo-controlled trialANNALS OF THE RHEUMATIC DISEASES2024-04-01第一作者
29Changes of cerebral structure and perfusion in subtypes of systemic sclerosis: a brain magnetic resonance imaging studyrheumatology2024-08通讯作者
  • 科研获奖Research Awards
# 获奖证书编号 奖项名称 获奖级别 获奖类别 获奖等级 获奖日期 颁奖单位 本单位是否为第一完成单位 完成单位排名 本人排序 备注
12009-257系统性红斑狼疮发病机制及诊断方法学研究省部级科学技术进步奖二等奖2010-01-01教育部112
220090202020P1010系统性红斑狼疮发病机制及诊断方法学研究省部级中华医学科技奖二等奖2009-12-25中华医学会110
  • 研究成果Research Findings
# 成果类型 项目/专利/新品种名称
1出版高水平专著北京协和医院 风湿免疫科疑难病诊断——协和医生临床思维例释
2出版高水平专著临床路径释义
3出版高水平专著风湿科主治医生1088问
4出版高水平专著内科学(第2版)