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神经科主任医师,教授,博士生导师。 主要专业方向:脑血管病、脑淀粉样血管病以及烟雾病等少见原因脑血管病;对缺血性脑卒中的发病机制及病因分型具有深刻的认识;近年来开始致力于脑小血管病尤其是脑淀粉样血管病的基础与临床影像研究,对脑淀粉样血管病的临床及影像有较深入的研究工作基础,发表相关文章并获得课题资助;基于北京协和医院多科协作的平台,完成青年卒中、烟雾病等少见病因脑血管病的基础与临床研究。作为课题负责人主持十四五科技创新2030重大项目课题;十三五期间作为子课题负责人与中国科技大学和华西医院合作,进行脑小血管病早期预警和预后评估研究,作为课题骨干先后参与十一五、十二五等多项国家级脑血管病课题;近年已发表第一/通讯作者SCI论文40篇,包括CVD、JAD、Int J Stroke、Trans Stroke Res、EJoN,Ann Neurol、Stroke等杂志;作为通讯作者之一执笔《脑小血管病转化医学专家共识》,参与撰写《BAD中国专家共识》和《急性缺血性卒中再灌注治疗医疗质量评价与改进专家建议》;学会/期刊任职:中国卒中学会医疗质量管理与促进分会副主任委员;国家脑卒中防治工程专家委员会脑小血管病分委会常委兼秘书长;中国卒中学会脑小血管病分委会常务委员;中华医学会神经病学分会神经康复学组委员;北京神经病学分会委员;JAD期刊associated editor;中华神经科杂志编委;中华医学杂志英文版及SCI期刊审稿专家。
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Team Profile
神经科主任医师,教授,博士生导师。 主要专业方向:脑血管病、脑淀粉样血管病以及烟雾病等少见原因脑血管病;对缺血性脑卒中的发病机制及病因分型具有深刻的认识;近年来开始致力于脑小血管病尤其是脑淀粉样血管病的基础与临床影像研究,对脑淀粉样血管病的临床及影像有较深入的研究工作基础,发表相关文章并获得课题资助;基于北京协和医院多科协作的平台,完成青年卒中、烟雾病等少见病因脑血管病的基础与临床研究。作为课题负责人主持十四五科技创新2030重大项目课题;十三五期间作为子课题负责人与中国科技大学和华西医院合作,进行脑小血管病早期预警和预后评估研究,作为课题骨干先后参与十一五、十二五等多项国家级脑血管病课题;近年已发表第一/通讯作者SCI论文40篇,包括CVD、JAD、Int J Stroke、Trans Stroke Res、EJoN,Ann Neurol、Stroke等杂志;作为通讯作者之一执笔《脑小血管病转化医学专家共识》,参与撰写《BAD中国专家共识》和《急性缺血性卒中再灌注治疗医疗质量评价与改进专家建议》;学会/期刊任职:中国卒中学会医疗质量管理与促进分会副主任委员;国家脑卒中防治工程专家委员会脑小血管病分委会常委兼秘书长;中国卒中学会脑小血管病分委会常务委员;中华医学会神经病学分会神经康复学组委员;北京神经病学分会委员;JAD期刊associated editor;中华神经科杂志编委;中华医学杂志英文版及SCI期刊审稿专家。
硕士研究生 1 名,博士研究生 3 名
# | 项目名称 | 起止日期 | 金额 | 项目类型 | 本人角色 |
---|---|---|---|---|---|
1 | 脑库数字化管理平台及相关数据库建设 | 2021-12-01 —— 2026-11-30 | 1000万 | 主持在研的国家或主持在研的国家或省部级科研项目科研项目 | 主持人 |
2 | 基于18F-AV45 PET和血清生物标志物的脑淀粉样血管病临床分型诊断和出血风险预测研究 | 2021-09-01 —— 2023-08-31 | 主持的企业/行业委托重大项目 | 主持人 |
# | 论文题目 | 期刊名称 | 发表年份 | 论文署名 |
---|---|---|---|---|
1 | Efficacy and safety of cinepazide maleate injection in patients with acute ischemic stroke: A multicenter, randomized, double-blind, placebo-controlled trial | BMC Neurology | 2020-07-01 | 第一作者 |
2 | Human urinary kallidinogenase in acute ischemic stroke: A single-arm, multicenter, phase IV study (RESK study) | CNS Neurosci Ther | 2021-08-17 | 第一作者 |
3 | Study protocol of Branch Atheromatous Disease?related stroke (BAD?study): a multicenter prospective cohort study | BMC Neurology | 2022-12-09 | 第一作者 |
4 | Consecutive Slices is More Effective than Transversal Diameter to Differentiate Mechanisms of Single Subcortical Infarctions in the Lenticulostriate Artery Territory | Front Neurol | 2019-04-09 | 通讯作者 |
5 | Cerebral Microbleeds Correlated with White Matter and Hippocampal Volumes in Community-Dwelling Populations. | JOURNAL OF ALZHEIMERS DISEASE | 2019-09-17 | 通讯作者 |
6 | Sex differences of ischemic stroke in young adults—A single-center Chinese cohort study | Journal of Stroke & Cerebrovascular Diseases | 2020-06-20 | 通讯作者 |
7 | Superficial Siderosis and Microbleed Restricted in Cortex Might Be Correlated to Atrophy and Cognitive Decline in Sneddon’s Syndrome | Frontiers in Neurology | 2020-08-14 | 通讯作者 |
8 | Needs assessment for a curriculum for difficult conversations -a survey from 5 Chinese accredited neurology residency training programs | BMC Medical Education | 2020-09-01 | 通讯作者 |
9 | Cerebral amyloid angiopathy-related inflammation: current status and future implications | CHINESE MEDICAL JOURNAL | 2021-04-01 | 通讯作者 |
10 | Correlation between total homocysteine and cerebral small vessel disease: A Mendelian randomization study | EUROPEAN JOURNAL OF NEUROLOGY | 2021-06-01 | 通讯作者 |
11 | White matter but not gary matter volumes are associated with cognition in community-dwelling Chinese populations | Journal of Alzheimer's Disease | 2021-09-16 | 通讯作者 |
12 | Response to letter to the editor by Zhang et al | EUROPEAN JOURNAL OF NEUROLOGY | 2022-02-20 | 通讯作者 |
13 | Fabry disease with aseptic meningitis: a case series and literature review of an underestimated clinical presentation | Current Medical Science | 2022-04-13 | 通讯作者 |
14 | Risk Factors of Ischemic Stroke in Young Adults: A Chinese Single-Center Study | Frontiers in Neurology | 2022-05-18 | 通讯作者 |
15 | comparing characteristics and outcomes of in-hospital stroke and community-onset stroke | JOURNAL OF NEUROLOGY | 2022-10-08 | 通讯作者 |
16 | Distinct lesion features and underlying mechanisms in patients with acute multiple infarcts in multiple cerebral territories | Frontiers in Neurology | 2023-01-16 | 通讯作者 |
17 | Clinical and prognostic characteristics of cerebral venous thrombosis at high altitude: a single-center retrospective study of Tibet | JOURNAL OF NEUROLOGY | 2023-02-08 | 通讯作者 |
18 | The Differential Effects of APOE 4 on Cerebral Volumetric Structures in Different Lifespan in Community-Dwelling Populations | JOURNAL OF ALZHEIMERS DISEASE | 2023-04-07 | 通讯作者 |
19 | Mechanisms of in-hospital acute ischemic stroke and their relevance to prognosis: A retrospective analysis | Journal of Stroke & Cerebrovascular Diseases | 2023-04-07 | 通讯作者 |
20 | Burden of dilated perivascular spaces in patients with moyamoya disease and moyamoya syndrome is related to middle cerebral artery stenosis | Frontiers in Neurology | 2023-06-05 | 通讯作者 |
21 | Blood-based biomarkers for Alzheimer's disease: a multicenter-based cross-sectional and longitudinal study in China | Science Bulletin | 2023-07-10 | 通讯作者 |
22 | Current status and value of testing antiphospholipid antibody in patients with acute ischemic stroke: a retrospective single-center study in China | NEUROLOGICAL SCIENCES | 2023-09-14 | 通讯作者 |
23 | The prevalence and prognosis of asymptomatic intracranial atherosclerosis in a community-based population: Results based on high-resolution magnetic resonance imaging | EUROPEAN JOURNAL OF NEUROLOGY | 2023-09-21 | 通讯作者 |
24 | Neurophobia among medical students and resident trainees in a tertiary comprehensive hospital in China | BMC Medical Education | 2023-11-02 | 通讯作者 |
25 | Circulating inflammatory biomarkers and risk of intracranial aneurysm: a Mendelian randomization study | EUROPEAN JOURNAL OF MEDICAL RESEARCH | 2024-01-03 | 通讯作者 |
26 | RNF213 in moyamoya disease: Genotype-phenotype association and the underlying mechanism | CHINESE MEDICAL JOURNAL | 2024-01-19 | 通讯作者 |
27 | Clinical characteristics of cerebral amyloid angiopathy and risk factors of cerebral amyloid angiopathy related intracerebral hemorrhage | JOURNAL OF NEUROLOGY | 2024-05-26 | 通讯作者 |
28 | Efficacy and safety of tirofiban in patients with acute branch atheromatous disease-related stroke (BRANT): a protocol for a randomised controlled trial | BMJ Open | 2024-06-10 | 通讯作者 |
无
# | 成果类型 | 项目/专利/新品种名称 |
---|---|---|
1 | 出版高水平专著 | 缺血性脑血管病 |