导师风采
康维明

个人信息

Personal Information

  • 性别:男
  • 导师类型:博导
  • 职称:主任医师
  • 该职称任职时间:201309

联系方式

Contact Information

  • 所属院系:北京协和医院
  • 所属专业:
  • 邮箱 : kangweiming@163.com
  • 工作电话 : 13810979989

个人简介

Personal Profile

康维明,男,主任医师,教授,博士生导师,外科学系副主任。1998年毕业于中国协和医科大学,医学博士,目前为中国医学科学院北京协和医院基本外科教授、主任医师、博士生导师。同时兼任中国抗癌协会胃癌专业委员会 委员;北京胃癌质控专家委员会 副主任委员;中国抗癌协会手术安全与质控专业委员会 常委;中华医学会肠外肠内营养学分会 常务委员;北京医学会肠外肠内营养学分会 副主任委员;中华医学会肠外肠内营养学分会NUSOC学组 组长;中国临床肿瘤学会胃肠间质瘤专家委员会 委员;中国医师协会胃肠间质瘤专家委员会 委员;北京围术期医学研究会减重代谢专业委员会 常委;中国研究型医院用状腺疾病专业委员会 委员,中华临床营养杂志特约审稿专家,中华诊断学杂志编委,中华医学教育探索杂志编委,中国医学科学院学报特约审稿专家,中华慈善总会格列卫代表医生,中国癌症基金会索坦代表医生,华夏医学科技奖评审委员会专家,北京市自然科学基金评审专家。曾赴德国、台湾学习腹腔镜手术技术、肥胖症及糖尿病手术技术。专业研究方向为胃肠道肿瘤基础临床研究、肠内肠外营养治疗基础临床研究、肥胖症及糖尿病手术基础临床研究。

团队简介

Team Profile

本团队是国内最早开展胃癌规范化诊疗的团队之一。2006年国内即开展胃癌新辅助治疗,2009年国内成熟开展胃癌全腹腔镜治疗,2019年成熟开展胃食管肿瘤多学科会诊,2021年成为国家胃癌质控中心单位。 本团队目前已建立北京协和医院胃癌数据库(病例数达1532例),包含患者病理、影像、治疗及预后随访等全套信息,以及全面的胃癌基础研究体系。团队长期致力于胃癌免疫逃逸研究和潜在免疫治疗靶点的探索,与加拿大麦吉尔大学戴维斯夫人研究所犹太医院Kostas Pantopoulos教授和哈佛大学布列根妇女医院Jonathan Fletcher教授均建立深度的学术和临床合作,近三年发表SCI论文31篇(中科院1区2篇),其中胃癌免疫治疗潜在靶点OTUB2的初步结果已发表于《Cell death discovery》和《Clinical and Translational Medicine》期刊,且获得北京市自然科学基金1项。

  • 研究方向Research Directions
胃肠外科
  • 在校研究生Current Graduate Students

硕士研究生 0 名,博士研究生 5 名

  • 科研项目Research Projects
# 项目名称 起止日期 金额 项目类型 本人角色
1非进展期胃癌(T1/T2)保留胃功能手术的临床研究2017-12-01 —— 2023-03-0118万元参与在研的国家或省部级科研项目主持者
2SHP2抑制剂提高PDGFRA外显子18突变GIST细胞对阿伐替尼敏感性的基础研究2022-01-01 —— 2024-01-0115万元主持在研的国家或省部级科研项目主持者
3 miR-30b/KRAS/GSTπ通路介导胃癌化疗耐药的分子机制研究 2020-01-01 —— 2023-12-3120万元主持在研的国家或省部级科研项目主持者
4减重代谢手术围手术期多学科主动管理诊疗规范的建立2020-10-01 —— 2022-10-0140万元主持在研的国家或省部级科研项目主持者
5OTUB2通过诱导胃癌PD-L1表达和M2型TAM极化促进胃癌进展的分子机制研究2023-01-01 —— 2025-12-0120万元主持在研的国家或省部级科研项目主持人
6非进展期胃癌(T1/T2)保留胃功能手术的临床研究2017-11-01 —— 2022-03-0118万主持在研的国家或省部级科研项目主持人
7胃癌规范化精准诊疗体系的建立2022-10-01 —— 2025-09-01100万元主持的企业/行业委托重大项目主持人
8miR-30b/KRAS/GST通路介导胃癌化疗耐药的分子机制研究2020-01-01 —— 2023-12-0120万元主持的企业/行业委托重大项目主持人
9袖状胃切除术对肠屏 障及肠道菌群的影响2019-10-01 —— 2021-09-013万元主持的企业/行业委托重大项目主持人
10新型胃超声技术在胃癌早期诊断及治疗中的临床应用转化研究2023-12-01 —— 2025-11-3050万元主持在研的国家或省部级科研项目主持人
11减重代谢手术围手术期多学科主动管理诊疗规范的建立2020-12-01 —— 2022-11-0140万元主持的企业/行业委托重大项目主持人
12ghrelin与胃肠间质瘤临床病理相关性及预后分析2019-06-01 —— 2021-06-015万元主持在研的国家或省部级科研项目主持人
13新型工业化三腔袋细菌培养及对胰岛素吸附作用对对照研究2020-09-01 —— 2021-12-3114万元主持在研的国家或省部级科研项目主持人
  • 发表论文Papers
# 论文题目 期刊名称 发表年份 论文署名
1The Role and Mechanism of microRNA-1224 in Human CancerFrontiers in oncology2022-06-12康维明
2The Sensitivity Prediction of Neoadjuvant Chemotherapy for Gastric CancerFrontiers in oncology2022-06-12康维明
3Rare Multiple Liver Lesions With AQ :1Am J Gastroenterol2022-06-12康维明
4The Association between Total Percent Fat and Serum Uric Acid in AdultsFrontiers in Nutrition2022-06-12康维明
5"Interpretation of the development of neoadjuvant therapy for gastric cancer based on the vicissitudes of the NCCN guidelines"WORLD J GASTRO ONCOL2022-06-12康维明
6A Place Where Angiolipoma Rarely Occurs-Case SeriesJournal of Internatinal Medical Research2022-06-12康维明
7腹腔镜辅助胃癌根治术后发生早期并发症的影响因素分析中华消化外科2022-06-12康维明
8The roles of non-coding RNAs in radiotherapy of gastrointestinal carcinomaFrontiers in Cell and Developmental Biology 2022-06-12康维明
9OTUB2 regulates KRT80 stability via deubiquitination and promotes tumour proliferation in gastric cancerCell Death Discovery 2022-06-12康维明
10The immune microenvironment in gastric cancer: Prognostic predictionFrontiers in oncology2022-06-12康维明
11Comparison of prognosis between microscopically positive and negative surgical margins for primary gastrointestinal stromal tumors: A systematic review and meta-analysisFrontiers in oncology2022-06-12康维明
12The Correlation of Total Percent Fat with Cardiovascular Disease-Related Lipid Biomarkers in AdultsFrontiers in Nutrition2022-06-12康维明
13Low urinary iodine is a protective factor of central lymph node metastasis in papillary thyroid cancer: a cross-sectional studyWorld Journal of Surgical Oncology2022-06-12康维明
14The Correlation of Type 2 Diabetes Status with Total Percent Fat in AdultsFrontiers in Nutrition2022-06-12康维明
15Comparison Among Endoscopic,Laparoscopic, and Open Resection for Relatively Small Gastric Gastrointestinal Stromal Tumors (<5 cm): A Bayesian Network Meta-AnalysisFrontiers in oncology2022-06-12康维明
16Changing patterns of thyroid cancer in different stages of Universal Salt Iodization in Peking Union Medical College Hospital, 1986–2018 Gland Surg2022-06-12康维明
17Eukaryotic initiation factor 5A2 and human digestive system neoplasmsWorld Journal of Gastrointestinal Oncology2019-06-15通讯作者
18Interpretation of the development of neoadjuvant therapy for gastric cancer based on the vicissitudes of the NCCN guidelinesWORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY2020-01-01通讯作者
19Exploration of the role of serum ghrelin in the diagnosis and treatment of digestive tract malignanciesJOURNAL OF INTERNATIONAL MEDICAL RESEARCH2020-05-01通讯作者
20Rare localization of angiolipoma in the gastrointestinal tract: a case seriesJOURNAL OF INTERNATIONAL MEDICAL RESEARCH2020-06-01通讯作者
21Changing patterns of thyroid cancer in different stages of Universal Salt Iodization in Peking Union Medical College Hospital, 1986-2018Gland Surgery2020-10-01通讯作者
22Rare multiple liver lesions with concentric circle patternAMERICAN JOURNAL OF GASTROENTEROLOGY2021-03-09通讯作者
23The Sensitivity Prediction of Neoadjuvant Chemotherapy for Gastric CancerFrontiers in Oncology2021-04-16通讯作者
24Low urinary iodine is a protective factor of central lymph node metastasis in papillary thyroid cancer: a cross-sectional studyWorld Journal of Surgical Oncology2021-07-12通讯作者
25Comparison Among Endoscopic, Laparoscopic, and Open Resection for Relatively Small Gastric Gastrointestinal Stromal Tumors (<5 cm): A Bayesian Network Meta-AnalysisFrontiers in Oncology2021-11-29通讯作者
26OTUB2 regulates KRT80 stability via deubiquitination and promotes tumour proliferation in gastric cancerCELL DEATH DISCOVERY2022-02-02通讯作者
27The Correlation of Total Percent Fat With Alterations in Cholesterol and Triglycerides in AdultsFRONTIERS IN NUTRITION2022-03-31通讯作者
28The Correlation of Prediabetes and Type 2 Diabetes With Adiposity in AdultsFRONTIERS IN NUTRITION2022-04-11通讯作者
29The Role and Mechanism of microRNA-1224 in Human CancerFRONTIERS IN ONCOLOGY2022-04-14通讯作者
30Comparison of prognosis between microscopically positive and negative surgical margins for primary gastrointestinal stromal tumors: A systematic review and meta-analysisFrontiers in Oncology2022-04-19通讯作者
31The Roles of Non-Coding RNAs in Radiotherapy of Gastrointestinal Carcinomafrontiers in cell and developmental biology2022-04-20通讯作者
32The Immune Microenvironment in Gastric Cancer: Prognostic PredictionFRONTIERS IN ONCOLOGY2022-04-28通讯作者
33The Association Between Total Percent Fat and Serum Uric Acid in AdultsFRONTIERS IN NUTRITION2022-05-20通讯作者
34Comparison of prognosis between neoadjuvant imatinib and upfront surgery for GIST: A systematic review and meta-analysisFrontiers in Pharmacology2022-08-29通讯作者
35Baseline splenic volume as a biomarker for clinical outcome and circulating lymphocyte count in gastric cancerFrontiers in Oncology2023-01-30通讯作者
36Comparisons of nutritional status and complications between patients with and without postoperative feeding jejunostomy tube in gastric cancer: a retrospective studyJournal of Gastrointestinal Oncology2023-02-28通讯作者
37Integrated analysis from multicentre studies identities m7G-related lncRNA-derived molecular subtypes and risk stratification systems for gastric cancerFrontiers in Immunology2023-03-02通讯作者
38Comprehensive analysis of cuproptosis-related immune biomarker signature to enhance prognostic accuracy in gastric cancerAging-US2023-04-07通讯作者
39Tumour-associated macrophages in gastric cancer: From function and mechanism to applicationClinical and Translational Medicine2023-08-22通讯作者
40Perioperative Enteral Immunonutrition Support for the Immune Function and Intestinal Mucosal Barrier in Gastric Cancer Patients Undergoing Gastrectomy: A Prospective Randomized Controlled StudyNutrients2023-11-27通讯作者
41Comprehensive integration of single-cell RNA and transcriptome RNA sequencing to establish a pyroptosis-related signature for improving prognostic prediction of gastric cancerComputational and Structural Biotechnology Journal2024-02-07通讯作者
42The clustering status of detached gastric cancer cells inhibits anoikis-induced ferroptosis to promote metastatic colonizationCancer Cell International2024-02-18通讯作者
43Identification and validation of protein biomarkers for predicting gastrointestinal stromal tumor recurrenceComputational and Structural Biotechnology Journal2024-02-22通讯作者
44Association between the gut microbiota, inflammatory factors, and colorectal cancer: evidence from Mendelian randomization analysisFrontiers in Microbiology2024-03-18通讯作者
45Integrated analysis of disulfidptosis-related immune genes signature to boost the efficacy of prognostic prediction in gastric cancerCancer Cell International2024-03-25通讯作者
  • 科研获奖Research Awards


  • 研究成果Research Findings
# 成果类型 项目/专利/新品种名称
1出版高水平专著中国国家处方集
2出版高水平专著协和临床外科手册
3出版高水平专著家庭肠外营养
4出版高水平专著临床营养学