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Contact Information
个人简介
Personal Profile
康维明,男,主任医师,教授,博士生导师,外科学系副主任。1998年毕业于中国协和医科大学,医学博士,目前为中国医学科学院北京协和医院基本外科教授、主任医师、博士生导师。同时兼任中国抗癌协会胃癌专业委员会 委员;北京胃癌质控专家委员会 副主任委员;中国抗癌协会手术安全与质控专业委员会 常委;中华医学会肠外肠内营养学分会 常务委员;北京医学会肠外肠内营养学分会 副主任委员;中华医学会肠外肠内营养学分会NUSOC学组 组长;中国临床肿瘤学会胃肠间质瘤专家委员会 委员;中国医师协会胃肠间质瘤专家委员会 委员;北京围术期医学研究会减重代谢专业委员会 常委;中国研究型医院用状腺疾病专业委员会 委员,中华临床营养杂志特约审稿专家,中华诊断学杂志编委,中华医学教育探索杂志编委,中国医学科学院学报特约审稿专家,中华慈善总会格列卫代表医生,中国癌症基金会索坦代表医生,华夏医学科技奖评审委员会专家,北京市自然科学基金评审专家。曾赴德国、台湾学习腹腔镜手术技术、肥胖症及糖尿病手术技术。专业研究方向为胃肠道肿瘤基础临床研究、肠内肠外营养治疗基础临床研究、肥胖症及糖尿病手术基础临床研究。
团队简介
Team Profile
本团队是国内最早开展胃癌规范化诊疗的团队之一。2006年国内即开展胃癌新辅助治疗,2009年国内成熟开展胃癌全腹腔镜治疗,2019年成熟开展胃食管肿瘤多学科会诊,2021年成为国家胃癌质控中心单位。 本团队目前已建立北京协和医院胃癌数据库(病例数达1532例),包含患者病理、影像、治疗及预后随访等全套信息,以及全面的胃癌基础研究体系。团队长期致力于胃癌免疫逃逸研究和潜在免疫治疗靶点的探索,与加拿大麦吉尔大学戴维斯夫人研究所犹太医院Kostas Pantopoulos教授和哈佛大学布列根妇女医院Jonathan Fletcher教授均建立深度的学术和临床合作,近三年发表SCI论文31篇(中科院1区2篇),其中胃癌免疫治疗潜在靶点OTUB2的初步结果已发表于《Cell death discovery》和《Clinical and Translational Medicine》期刊,且获得北京市自然科学基金1项。
硕士研究生 0 名,博士研究生 5 名
# | 项目名称 | 起止日期 | 金额 | 项目类型 | 本人角色 |
---|---|---|---|---|---|
1 | 非进展期胃癌(T1/T2)保留胃功能手术的临床研究 | 2017-12-01 —— 2023-03-01 | 18万元 | 参与在研的国家或省部级科研项目 | 主持者 |
2 | SHP2抑制剂提高PDGFRA外显子18突变GIST细胞对阿伐替尼敏感性的基础研究 | 2022-01-01 —— 2024-01-01 | 15万元 | 主持在研的国家或省部级科研项目 | 主持者 |
3 | miR-30b/KRAS/GSTπ通路介导胃癌化疗耐药的分子机制研究 | 2020-01-01 —— 2023-12-31 | 20万元 | 主持在研的国家或省部级科研项目 | 主持者 |
4 | 减重代谢手术围手术期多学科主动管理诊疗规范的建立 | 2020-10-01 —— 2022-10-01 | 40万元 | 主持在研的国家或省部级科研项目 | 主持者 |
5 | OTUB2通过诱导胃癌PD-L1表达和M2型TAM极化促进胃癌进展的分子机制研究 | 2023-01-01 —— 2025-12-01 | 20万元 | 主持在研的国家或省部级科研项目 | 主持人 |
6 | 非进展期胃癌(T1/T2)保留胃功能手术的临床研究 | 2017-11-01 —— 2022-03-01 | 18万 | 主持在研的国家或省部级科研项目 | 主持人 |
7 | 胃癌规范化精准诊疗体系的建立 | 2022-10-01 —— 2025-09-01 | 100万元 | 主持的企业/行业委托重大项目 | 主持人 |
8 | miR-30b/KRAS/GST通路介导胃癌化疗耐药的分子机制研究 | 2020-01-01 —— 2023-12-01 | 20万元 | 主持的企业/行业委托重大项目 | 主持人 |
9 | 袖状胃切除术对肠屏 障及肠道菌群的影响 | 2019-10-01 —— 2021-09-01 | 3万元 | 主持的企业/行业委托重大项目 | 主持人 |
10 | 新型胃超声技术在胃癌早期诊断及治疗中的临床应用转化研究 | 2023-12-01 —— 2025-11-30 | 50万元 | 主持在研的国家或省部级科研项目 | 主持人 |
11 | 减重代谢手术围手术期多学科主动管理诊疗规范的建立 | 2020-12-01 —— 2022-11-01 | 40万元 | 主持的企业/行业委托重大项目 | 主持人 |
12 | ghrelin与胃肠间质瘤临床病理相关性及预后分析 | 2019-06-01 —— 2021-06-01 | 5万元 | 主持在研的国家或省部级科研项目 | 主持人 |
13 | 新型工业化三腔袋细菌培养及对胰岛素吸附作用对对照研究 | 2020-09-01 —— 2021-12-31 | 14万元 | 主持在研的国家或省部级科研项目 | 主持人 |
# | 论文题目 | 期刊名称 | 发表年份 | 论文署名 |
---|---|---|---|---|
1 | The Role and Mechanism of microRNA-1224 in Human Cancer | Frontiers in oncology | 2022-06-12 | 康维明 |
2 | The Sensitivity Prediction of Neoadjuvant Chemotherapy for Gastric Cancer | Frontiers in oncology | 2022-06-12 | 康维明 |
3 | Rare Multiple Liver Lesions With AQ :1 | Am J Gastroenterol | 2022-06-12 | 康维明 |
4 | The Association between Total Percent Fat and Serum Uric Acid in Adults | Frontiers in Nutrition | 2022-06-12 | 康维明 |
5 | "Interpretation of the development of neoadjuvant therapy for gastric cancer based on the vicissitudes of the NCCN guidelines" | WORLD J GASTRO ONCOL | 2022-06-12 | 康维明 |
6 | A Place Where Angiolipoma Rarely Occurs-Case Series | Journal of Internatinal Medical Research | 2022-06-12 | 康维明 |
7 | 腹腔镜辅助胃癌根治术后发生早期并发症的影响因素分析 | 中华消化外科 | 2022-06-12 | 康维明 |
8 | The roles of non-coding RNAs in radiotherapy of gastrointestinal carcinoma | Frontiers in Cell and Developmental Biology | 2022-06-12 | 康维明 |
9 | OTUB2 regulates KRT80 stability via deubiquitination and promotes tumour proliferation in gastric cancer | Cell Death Discovery | 2022-06-12 | 康维明 |
10 | The immune microenvironment in gastric cancer: Prognostic prediction | Frontiers in oncology | 2022-06-12 | 康维明 |
11 | Comparison of prognosis between microscopically positive and negative surgical margins for primary gastrointestinal stromal tumors: A systematic review and meta-analysis | Frontiers in oncology | 2022-06-12 | 康维明 |
12 | The Correlation of Total Percent Fat with Cardiovascular Disease-Related Lipid Biomarkers in Adults | Frontiers in Nutrition | 2022-06-12 | 康维明 |
13 | Low urinary iodine is a protective factor of central lymph node metastasis in papillary thyroid cancer: a cross-sectional study | World Journal of Surgical Oncology | 2022-06-12 | 康维明 |
14 | The Correlation of Type 2 Diabetes Status with Total Percent Fat in Adults | Frontiers in Nutrition | 2022-06-12 | 康维明 |
15 | Comparison Among Endoscopic,Laparoscopic, and Open Resection for Relatively Small Gastric Gastrointestinal Stromal Tumors (<5 cm): A Bayesian Network Meta-Analysis | Frontiers in oncology | 2022-06-12 | 康维明 |
16 | Changing patterns of thyroid cancer in different stages of Universal Salt Iodization in Peking Union Medical College Hospital, 1986–2018 | Gland Surg | 2022-06-12 | 康维明 |
17 | Eukaryotic initiation factor 5A2 and human digestive system neoplasms | World Journal of Gastrointestinal Oncology | 2019-06-15 | 通讯作者 |
18 | Interpretation of the development of neoadjuvant therapy for gastric cancer based on the vicissitudes of the NCCN guidelines | WORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY | 2020-01-01 | 通讯作者 |
19 | Exploration of the role of serum ghrelin in the diagnosis and treatment of digestive tract malignancies | JOURNAL OF INTERNATIONAL MEDICAL RESEARCH | 2020-05-01 | 通讯作者 |
20 | Rare localization of angiolipoma in the gastrointestinal tract: a case series | JOURNAL OF INTERNATIONAL MEDICAL RESEARCH | 2020-06-01 | 通讯作者 |
21 | Changing patterns of thyroid cancer in different stages of Universal Salt Iodization in Peking Union Medical College Hospital, 1986-2018 | Gland Surgery | 2020-10-01 | 通讯作者 |
22 | Rare multiple liver lesions with concentric circle pattern | AMERICAN JOURNAL OF GASTROENTEROLOGY | 2021-03-09 | 通讯作者 |
23 | The Sensitivity Prediction of Neoadjuvant Chemotherapy for Gastric Cancer | Frontiers in Oncology | 2021-04-16 | 通讯作者 |
24 | Low urinary iodine is a protective factor of central lymph node metastasis in papillary thyroid cancer: a cross-sectional study | World Journal of Surgical Oncology | 2021-07-12 | 通讯作者 |
25 | Comparison Among Endoscopic, Laparoscopic, and Open Resection for Relatively Small Gastric Gastrointestinal Stromal Tumors (<5 cm): A Bayesian Network Meta-Analysis | Frontiers in Oncology | 2021-11-29 | 通讯作者 |
26 | OTUB2 regulates KRT80 stability via deubiquitination and promotes tumour proliferation in gastric cancer | CELL DEATH DISCOVERY | 2022-02-02 | 通讯作者 |
27 | The Correlation of Total Percent Fat With Alterations in Cholesterol and Triglycerides in Adults | FRONTIERS IN NUTRITION | 2022-03-31 | 通讯作者 |
28 | The Correlation of Prediabetes and Type 2 Diabetes With Adiposity in Adults | FRONTIERS IN NUTRITION | 2022-04-11 | 通讯作者 |
29 | The Role and Mechanism of microRNA-1224 in Human Cancer | FRONTIERS IN ONCOLOGY | 2022-04-14 | 通讯作者 |
30 | Comparison of prognosis between microscopically positive and negative surgical margins for primary gastrointestinal stromal tumors: A systematic review and meta-analysis | Frontiers in Oncology | 2022-04-19 | 通讯作者 |
31 | The Roles of Non-Coding RNAs in Radiotherapy of Gastrointestinal Carcinoma | frontiers in cell and developmental biology | 2022-04-20 | 通讯作者 |
32 | The Immune Microenvironment in Gastric Cancer: Prognostic Prediction | FRONTIERS IN ONCOLOGY | 2022-04-28 | 通讯作者 |
33 | The Association Between Total Percent Fat and Serum Uric Acid in Adults | FRONTIERS IN NUTRITION | 2022-05-20 | 通讯作者 |
34 | Comparison of prognosis between neoadjuvant imatinib and upfront surgery for GIST: A systematic review and meta-analysis | Frontiers in Pharmacology | 2022-08-29 | 通讯作者 |
35 | Baseline splenic volume as a biomarker for clinical outcome and circulating lymphocyte count in gastric cancer | Frontiers in Oncology | 2023-01-30 | 通讯作者 |
36 | Comparisons of nutritional status and complications between patients with and without postoperative feeding jejunostomy tube in gastric cancer: a retrospective study | Journal of Gastrointestinal Oncology | 2023-02-28 | 通讯作者 |
37 | Integrated analysis from multicentre studies identities m7G-related lncRNA-derived molecular subtypes and risk stratification systems for gastric cancer | Frontiers in Immunology | 2023-03-02 | 通讯作者 |
38 | Comprehensive analysis of cuproptosis-related immune biomarker signature to enhance prognostic accuracy in gastric cancer | Aging-US | 2023-04-07 | 通讯作者 |
39 | Tumour-associated macrophages in gastric cancer: From function and mechanism to application | Clinical and Translational Medicine | 2023-08-22 | 通讯作者 |
40 | Perioperative Enteral Immunonutrition Support for the Immune Function and Intestinal Mucosal Barrier in Gastric Cancer Patients Undergoing Gastrectomy: A Prospective Randomized Controlled Study | Nutrients | 2023-11-27 | 通讯作者 |
41 | Comprehensive integration of single-cell RNA and transcriptome RNA sequencing to establish a pyroptosis-related signature for improving prognostic prediction of gastric cancer | Computational and Structural Biotechnology Journal | 2024-02-07 | 通讯作者 |
42 | The clustering status of detached gastric cancer cells inhibits anoikis-induced ferroptosis to promote metastatic colonization | Cancer Cell International | 2024-02-18 | 通讯作者 |
43 | Identification and validation of protein biomarkers for predicting gastrointestinal stromal tumor recurrence | Computational and Structural Biotechnology Journal | 2024-02-22 | 通讯作者 |
44 | Association between the gut microbiota, inflammatory factors, and colorectal cancer: evidence from Mendelian randomization analysis | Frontiers in Microbiology | 2024-03-18 | 通讯作者 |
45 | Integrated analysis of disulfidptosis-related immune genes signature to boost the efficacy of prognostic prediction in gastric cancer | Cancer Cell International | 2024-03-25 | 通讯作者 |
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# | 成果类型 | 项目/专利/新品种名称 |
---|---|---|
1 | 出版高水平专著 | 中国国家处方集 |
2 | 出版高水平专著 | 协和临床外科手册 |
3 | 出版高水平专著 | 家庭肠外营养 |
4 | 出版高水平专著 | 临床营养学 |