导师风采
李晓光
个人信息
Personal Information
- 性别：男
- 导师类型：博士生导师
- 职称：教授
- 该职称任职时间：2009
联系方式
Contact Information
- 所属院系：北京医院
- 所属专业：
- 邮箱 : xglee88@126.com
- 工作电话 : 85132997
个人简介
Personal Profile
1990年9月至1996年7月在中国医科大学七年制学习，然后转学入中国协和医科大学八年制临床医学专业，师从国内著名放射学家和介入治疗专家金征宇教授，1998年7月毕业并获得医学博士学位，1998年8月分配到北京协和医院放射科工作，全面轮转放射科各亚专业，先后担任住院医师、总住院医师，2001年9月晋升为主治医师，开始固定从事介入诊疗工作，2004年通过卫生部评审取得副主任医师资格，2005年9月聘任为副主任医师。2006年4月赴美国密西根大学医院放射科从事血管介入工作一年，期间取得美国密西根州临时医师执照，完成各种血管介入手术近千例，取得Fellowship培训证书。2007年3月归国回北京协和医院放射科继续工作。2009年通过卫生部评审取得主任医师资格，2011年9月起聘任为北京协和医院放射科主任医师。2012年取得博士生导师资格。2016年8月调入北京医院，组建肿瘤微创治疗中心并担任科主任。2023年11月起兼任放射科主任。
团队简介
Team Profile
待补充更新
- 研究方向Research Directions
肿瘤影像,肿瘤介入,肿瘤免疫
- 在校研究生Current Graduate Students
硕士研究生 0 名，博士研究生 2 名
- 科研项目Research Projects
| # | 项目名称 | 起止日期 | 金额 | 项目类型 | 本人角色 |
|---|---|---|---|---|---|
| 1 | PTC技术指导下多模态介入治疗无法手术或放化疗不耐受及失败的三期非小细胞肺癌 | 2022-04-01 —— | 41.6 | 主持在研的国家或省部级科研项目 | 主持者 |
| 2 | 老年不可手术切除Ⅲ期非小细胞肺癌综合微创介入治疗模式的临床研究及预后因素分析 | 2021-01-01 —— | 53.0 | 主持者 | |
| 3 | 泌尿生殖系统肿瘤复合式冷热消融应用评价与示范研究 | 2023-11 —— 2026-10 | 100 | 主持在研的国家或省部级科研项目 | 主持人 |
| 4 | CT 引导下微波消融治疗老年早期肺癌安全性提升及疗效评价关键技术研究 | 2023-10 —— 2026-10 | 100 | 主持在研的国家或省部级科研项目 | 主持人 |
| 5 | DEB-BACE 用于常规治疗失败、拒绝或不适合行常规 治疗的 II/III 期 NSCLC 的疗效与安全性：一项前瞻性、多中心、单臂临床研究 | 2021-05 —— 2024-10 | 5.83 | 主持的企业/行业委托重大项目 | 主持人 |
- 发表论文Papers
| # | 论文题目 | 期刊名称 | 发表年份 | 论文署名 |
|---|---|---|---|---|
| 1 | Intratumoral Injection of Hypertonic Glucose in Treating Refractory Pneumothorax Caused by Microwave Ablation: a Preliminary Study | Cardiovasc Intervent Radiol | 2019-06 | 通讯作者 |
| 2 | The efficacy of drug-eluting beads bronchial arterial chemoembolization loaded with gemcitabine for treatment of non-small cell lung cancer | Thoracic Cancer | 2019-09 | 通讯作者 |
| 3 | Comparison of survival benefits of nephron-sparing intervention or active surveillance for patients with localized renal masses: a systematic review and meta-analysis | BMC Urol | 2019-08 | 通讯作者 |
| 4 | Synchronous core-needle biopsy and microwave ablation for highly suspicious malignant pulmonary nodule via a coaxial cannula | J Can Res Ther | 2019-11 | 通讯作者 |
| 5 | Computed tomography-guided percutaneous core-needle biopsy after thermal ablation for lung groundglass opacities: Is the method sound? | J Can Res Ther | 2019-11 | 第一作者 |
| 6 | Seven case reports on the prevention of hemorrhage after percutaneous computed tomography-guided core-needle biopsy of the spleen | J Cancer Res Ther | 2020-09 | 通讯作者 |
| 7 | Pneumothorax triggered by EGFR-tyrosine kinase inhibitors in three microwave ablation candidates: A review of the literature | Thorac Cancer | 2020-07 | 通讯作者 |
| 8 | The blood cells in NSCLC and the changes after RFA | Int J Hyperthermia | 2020-01 | 通讯作者 |
| 9 | Advances in study of the sequence of lung tumor biopsy and thermal ablation | Thorac Cancer | 2021-02 | 通讯作者 |
| 10 | Microwave Ablation for the Treatment of Cancer in Patients with Nephrotic Syndrome | Cardiovasc Intervent Radiol | 2021-05 | 通讯作者 |
| 11 | Cryoablation, high-intensity focused ultrasound, irreversible electroporation, and vascular-targeted photodynamic therapy for prostate cancer: a systemic review and meta-analysis | Int J Clin Oncol | 2021-03 | 通讯作者 |
| 12 | Proton Pump Inhibitors Increase the Risk of Early Biliary Infection After Placement of Percutaneous Transhepatic Biliary Stents | J Vasc Interv Radiol | 2021-02 | 通讯作者 |
| 13 | Risk prediction of pleural effusion in lung malignancy patients treated with CT-guided percutaneous microwave ablation: a nomogram and artificial neural network model | Int J Hyperthermia | 2021-06 | 通讯作者 |
| 14 | Risk prediction of pneumothorax in lung malignancy patients treated with percutaneous microwave ablation: development of nomogram model | Int J Hyperthermia | 2021-06 | 通讯作者 |
| 15 | Survival prediction for non-small cell lung cancer patients treated with CT-guided microwave ablation: development of a prognostic nomogram | Int J Hyperthermia | 2021-06 | 通讯作者 |
| 16 | A Comparative Study of Cavitary and Non-Cavitary Non-small Cell Lung Cancer Patients Treated with CT-Guided Microwave Ablation | J Vasc Interv Radiol | 2021-08 | 通讯作者 |
| 17 | Microwave ablation of lung malignancies with coexisting severe emphysema: a retrospective analysis of safety and efficacy in 26 patients | Int J Hyperthermia | 2021-01 | 通讯作者 |
| 18 | Computed tomography-guided microwave ablation for the treatment of non-small cell lung cancer patients with and without adjacent lobe invasion: A comparative study | Thorac Cancer | 2021-10 | 通讯作者 |
| 19 | Synchronous microwave ablation followed by core-needle biopsy via a coaxial cannula for highly suspected malignant lung ground-glass opacities: A single-center, single-arm retrospective study | Thorac Cancer | 2021-12 | 通讯作者 |
| 20 | Comparison of the radiofrequency ablation versus laparoscopic adrenalectomy for aldosterone-producing adenoma: a meta-analysis of perioperative outcomes and safety | Updates Surg | 2021-08 | 通讯作者 |
| 21 | Correlations of RENAL, PADUA and NePhRO Scores With Complications and Outcomes in Patients After CT-Guided Microwave Ablation of Renal Tumors | Altern Ther Health Med | 2021-09 | 通讯作者 |
| 22 | Sintilimab plus Bronchial Arterial Infusion Chemotherapy/Drug-Eluting Embolic Chemoembolization for Advanced Non-Small Cell Lung Cancer: A Preliminary Study of 10 Patients | J Vasc Interv Radiol | 2021-12 | 通讯作者 |
| 23 | Multicentre study of microwave ablation for pulmonary oligorecurrence after radical resection of non-small-cell lung cancer | Br J Cancer | 2021-08 | 通讯作者 |
| 24 | Combination of thermal ablation and activated functional killer cells immunotherapy for cancer: A retrospective study | J Cancer Res Ther | 2021-07 | 通讯作者 |
| 25 | Local progression after computed tomography-guided microwave ablation in non-small cell lung cancer patients: prediction using a nomogram model | Int J Hyperthermia | 2021-01 | 通讯作者 |
| 26 | Drug-Eluting Bead Bronchial Arterial Chemoembolization With and Without Microwave Ablation for the Treatment of Advanced and Standard Treatment-Refractory/Ineligible Non-Small Cell Lung Cancer: A Comparative Study | Front Oncol | 2022-03 | 通讯作者 |
| 27 | Computed tomography (CT)-guided percutaneous coaxial biopsy combined with microwave ablation for the treatment of renal masses | Minim Invasive Ther Allied Technol | 2022-03 | 通讯作者 |
| 28 | Computed tomography-guided microwave ablation for non-small cell lung cancer patients on antithrombotic therapy: a retrospective cohort study | Quant Imaging Med Surg | 2022-06 | 通讯作者 |
| 29 | Comparison of analgesic effect in celiac plexus neurolysis: ethanol injection with or without iodine-125 radioactive seeds implantation | J Cancer Res Ther | 2022-05-31 | 通讯作者 |
| 30 | Liquid biopsy assay for pulmonary adenocarcinoma using supernatants from core-needle biopsy specimens | Thoracic Cancer | 2022-12 | 通讯作者 |
| 31 | Nerve Injury and Regeneration after Neurolysis: Ethanol versus Ethanol with Brachytherapy in Rabbits | J Vasc Interv Radiol | 2022-09 | 通讯作者 |
| 32 | Microwave ablation combined with anti-PD-1/CTLA-4 therapy induces an antitumor immune response to renal cell carcinoma in a murine model | Cell Cycle | 2022-01 | 通讯作者 |
| 33 | Iodine-125 Seed Implantation and Transarterial Chemoinfusion Combined with Immune Checkpoint Inhibitors for Thoracic SMARCA4-UT | J Vasc Interv Radiol | 2023-01 | 通讯作者 |
| 34 | Standard treatment-refractory/ineligible small cell lung cancer treated with drug-eluting beads bronchial arterial chemoembolization: a retrospective cohort study | Quant Imaging Med Surg | 2023-01 | 通讯作者 |
| 35 | Effects of tract embolization on pneumothorax rate after percutaneous pulmonary microwave ablation: a rabbit study | Int J Hyperthermia | 2023-01 | 通讯作者 |
| 36 | Percutaneous microwave ablation-induced pulmonary artery pseudoaneurysm: a case description and literature analysis | Quant Imaging Med Surg | 2023-02 | 通讯作者 |
| 37 | Diagnostic performance and safety of percutaneous fine-needle aspiration immediately before microwave ablation for pulmonary ground-glass nodules | Quant Imaging Med Surg | 2023-06 | 通讯作者 |
| 38 | Microwave Ablation for Inoperable Stage I Non-small Cell Lung Cancer in Patients Aged ≥ 70 Years: A Prospective, Single-center Study | J Vasc Interv Radiol | 2023-10 | 通讯作者 |
| 39 | Effects of microwave ablation on cysts and cystic neoplasms with tissue-mimicking model: an ex vivo study | Int J Hyperthermia | 2023-01 | 通讯作者 |
| 40 | Percutaneous core-needle biopsy before and immediately after coaxial microwave ablation in solid non-small cell lung cancer: the comparison of genomic testing from specimens | Cancer Imaging | 2023-01 | 通讯作者 |
| 41 | Drug-eluting beads bronchial arterial chemoembolization/bronchial arterial infusion chemotherapy with and without PD-1 blockade for advanced non-small cell lung cancer: a comparative single-center cohort study | Quant Imaging Med Surg | 2023-06 | 通讯作者 |
| 42 | Microwave ablation with a blunt-tip antenna for pulmonary ground-glass nodules: a retrospective, multicenter, case-control study | Radiol Med | 2023-09 | 通讯作者 |
- 科研获奖Research Awards
无
- 研究成果Research Findings
| # | 成果类型 | 项目/专利/新品种名称 |
|---|---|---|
| 1 | 作为主创人员获得授权的发明专利和新品种 | 一种具有监测功能的气胸单向排气装置 |
| 2 | 作为主创人员获得授权的发明专利和新品种 | 一种球囊消融导管 |
| 3 | 作为主创人员获得授权的发明专利和新品种 | 一种囊性肿瘤微波消融针 |
| 4 | 作为主创人员获得授权的发明专利和新品种 | 用于提取痰液标本无细胞上清中游离DNA的化痰液 |
| 5 | 出版高水平专著 | 国家权威经典--中华影像医学 《介入放射学卷》 |
| 6 | 出版高水平专著 | 肺部肿瘤消融治疗 |
| 7 | 出版高水平专著 | CT引导下肺部肿瘤热消融图谱 |