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黎明,男,医学博士,北京协和医院内分泌科研究员、博士研究生导师。北京市科技新星计划入选者。2013-2015 美国宾夕法尼亚大学(费城儿童医院)2年 Visiting Scientist; 兼任《中华糖尿病杂志》、《中国糖尿病杂志》、《国际糖尿病》等多个期刊编委及《Heliyou》期刊 Associate Editor,BMC Endocrine Disorders 编委以及《International Journal of Obesity》、《EBioMedicine》等多种SCI期刊审稿专家;兼任中华医学会糖尿病学分会基础与转化医学学组委员、妇幼健康研究会肥胖与控制专业委员会常委等职。1995年中国协和医科大学研究生毕业获医学硕士学位,2010年北京协和医学院获博士学位。1995年留协和医院内分泌科工作至今,主要致力于肥胖、糖尿病等胰岛素抵抗相关疾病早期预警和发病机制研究。目前作为首都十大疾病攻关项目专家,专注于受国家重点研发计划、国家自然基金、北京市科技重点项目等资助的 “北京儿童青少年代谢综合征队列研究(The Beijing Child and Adolescent Metabolic Syndrome study, BCAMS)”,基于国际珍贵的儿童肥胖大型前瞻性队列10年深度随访,从环境因素、遗传、表观遗传以及蛋白组和代谢组学等方面多组学探寻预示肥胖、糖尿病发生、发展的关键标志物。目前已发表论文140余篇,其中SCI 60余篇,部分论文发表在《J Clin Endocrinol Metab》、《International Journal of Obesity》、《Clinical Nutrition》、《EBioMedicine》、《Sleep》、《 Cardiovascular Diabetology》、《Metabolism》等专业著名期刊,并在顶级国际学术会议如美国糖尿病科学年会(ADA)上交流论文20余篇。已获发明专利2项及科研成果奖4项。率先在中国儿童青少年人群开展“代谢健康型肥胖和代谢异常型肥胖的精准识别和预警研究”,获首都十大疾病科技攻关创新型进展奖;主笔发布第一版“中国儿童代谢健康型肥胖的定义和筛查专家共识”,参与“儿童代谢健康型肥胖”国际专家共识制定,有关肥胖的研究成果受到CCTV、人民日报等众多媒体多次报道。
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硕士研究生 0 名,博士研究生 0 名
# | 项目名称 | 起止日期 | 金额 | 项目类型 | 本人角色 |
---|---|---|---|---|---|
1 | lncRNA 编码介导的宫内不良营养环境导致子代糖脂代谢紊乱的跨代机制” | 2019-01-01 —— 2022-12-30 | 57.0 | 参与在研的国家或省部级科研项目 | 参与者 |
2 | 瘦素、脂联素在睡眠不足导致心脏损伤的作用机制” | 2020-01-01 —— 2023-12-30 | 55.0 | 参与在研的国家或省部级科研项目 | 参与者 |
3 | 基于单克隆抗体的脂联素诊断试剂盒在肥胖/糖尿病防治中的转化应用 | 2020-05-30 —— 2023-06-01 | 120.0 | 主持在研的国家或省部级科研项目 | 主持者 |
# | 论文题目 | 期刊名称 | 发表年份 | 论文署名 |
---|---|---|---|---|
1 | Impact of parental smoking on adipokine profiles and cardiometabolic risk factors in Chinese children. | Atherosclerosis | 2022-06-02 | 黎明 |
2 | A Novel Type of Extreme Insulin Resistance: Nonhypoglycemic Insulin Autoimmune Syndrome | J Clin Endocrinol Metab | 2022-06-02 | 黎明 |
3 | Genetic variations in adiponectin levels and dietary patterns on metabolic health among children with normal weight versus obesity: the BCAMS study. | Int J Obes (Lond). | 2022-06-02 | 黎明 |
4 | Childhood sleep duration modifies the polygenic risk for obesity in youth through leptin pathway: the?Beijing?Child and Adolescent Metabolic Syndrome cohort study. | Int J Obes (Lond) | 2022-06-02 | 黎明 |
5 | Adipose Tissue Mediates the Associations of Birth Weight With Glucose Metabolism Disorders in Children. | Obesity | 2022-06-02 | 黎明 |
6 | Insulin resistance, beta-cell function, adipokine profiles and cardiometabolic risk factors among Chinese youth with isolated impaired fasting glucose versus impaired glucose tolerance: the?BCAMS?study. | BMJ Open Diabetes Res Care | 2022-06-02 | 黎明 |
7 | Vitamin D levels are associated with metabolic syndrome in adolescents and young adults: The BCAMS study | Clin Nutr | 2022-06-02 | 黎明 |
8 | FGF21 deficiency?is associated with childhood obesity, insulin resistance and?hypoadiponectinemia: The BCAMS Study. | Diabetes & Metabolism | 2022-06-02 | 黎明 |
9 | Associations of breast milk adiponectin, leptin, insulin and ghrelin with maternal characteristics and early infant growth: a longitudinal study. | Br J Nutr. | 2022-06-02 | 黎明 |
10 | Loss of Cardio-Protective Effects at the CDH13 Locus Due to Gene-Sleep Interaction: The BCAMS Study | Ebiomedicine | 2022-06-02 | 黎明 |
11 | Serum resistin correlates with central obesity but weakly with insulin resistance in Chinese children and adolescents. | Int J Obes (Lond) | 2022-06-02 | 黎明 |
12 | Childhood retinol-binding protein 4 (RBP4) levels predicting the 10-year risk of insulin resistance and metabolic syndrome: the BCAMS study. | Cardiovascular Diabetology. | 2022-06-02 | 黎明 |
13 | Angiopoietin-Like Protein 8/Leptin Crosstalk Influences Cardiac Mass in Youths With Cardiometabolic Risk: The BCAMS Study. | Front Endocrinol (Lausanne) | 2022-06-02 | 黎明 |
14 | Sleep Duration and Cardiometabolic Risk Among Chinese School-aged Children: Do Adipokines Play a Mediating Role? | SLEEP | 2022-06-02 | 黎明 |
15 | Role of adipokines FGF21, leptin and adiponectin in self-concept of youths with obesity. | Eur Neuropsychopharmacol. | 2022-06-02 | 黎明 |
16 | Leptin-adiponectin imbalance as a marker of metabolic syndrome among Chinese children and adolescents: The BCAMS study. | PLOS ONE | 2022-06-02 | 黎明 |
17 | Interaction between early environment and genetic predisposition instigates the metabolically obese, normal weight phenotype in children: findings from the?BCAMS?study. | Eur J Endocrinol | 2022-06-02 | 黎明 |
18 | Plasma adiponectin levels in relation to prognosis in patients with angiographic coronary artery disease. | Metabolism. | 2022-06-02 | 黎明 |
19 | Vitamin D modifies the associations between circulating betatrophin and cardiometabolic risk factors among youths at risk for metabolic syndrome | Cardiovasc Diabetol. | 2022-06-02 | 黎明 |
20 | Puberty Status Modifies the Effects of Genetic Variants, Lifestyle Factors and Their Interactions on Adiponectin: The BCAMS Study. | Front Endocrinol (Lausanne). | 2022-06-02 | 黎明 |
21 | Insulin resistance determined by Homeostasis Model Assessment (HOMA) and associations with metabolic syndrome among Chinese children and teenagers. | Diabetol Metab Syndr | 2022-06-02 | 黎明 |
22 | Association between sleep duration and cardiac structure in youths at risk for metabolic syndrome | Sci. Rep. | 2022-06-02 | 黎明 |
23 | Identification of Genetic and Environmental Factors Predicting Metabolically Healthy Obesity in Children: Data From the BCAMS Study | J Clin Endocrinol Metab | 2022-06-02 | 黎明 |
24 | Circulating Osteonectin and Adipokine Profiles in Relation to Metabolically Healthy Obesity in Chinese Children: Findings From?BCAMS | J Am Heart Assoc | 2022-06-02 | 黎明 |
# | 获奖证书编号 | 奖项名称 | 获奖级别 | 获奖类别 | 获奖等级 | 获奖日期 | 颁奖单位 | 本单位是否为第一完成单位 | 完成单位排名 | 本人排序 | 备注 |
---|---|---|---|---|---|---|---|---|---|---|---|
1 | 2006-J-2-046 | 山西省科学技术进步奖 | 省部级 | 科技进步奖、哲学社科奖 | 二等奖 | 2006-12-01 | 山西省科学技术委员会 | 否 | 2 | 2 | |
2 | 2008-J-2-051 | 山西省科技进步奖 | 省部级 | 科技进步奖、哲学社科奖 | 二等奖 | 2009-01-01 | 山西省科技厅 | 否 | 2 | 3 | |
3 | 无 | 儿童代谢“健康型”肥胖和代谢异常型肥胖的精准识别和预警研究 | 省部级 | 其他省部级奖励 | 其他 | 2016-11-01 | 北京市科委 | 是 | 1 | 1 |
# | 成果类型 | 项目/专利/新品种名称 |
---|---|---|
1 | 作为主创人员获得授权的发明专利和新品种 | 抗人脂联素的单克隆抗体及其应用 |