个人信息
Personal Information
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Contact Information
个人简介
Personal Profile
教授、博士生导师。北京协和医学院皮肤性病学系主任、皮肤科主任。中国医疗保健国际交流促进会皮肤科分会主任委员。国家皮肤与免疫疾病临床医学研究中心副主任。中国医师协会皮肤科分会副会长、中华医学会皮肤科分会病理学组副组长。华夏皮肤影像人工智能协作组组长。亚洲皮肤病学会(ADA)理事,亚洲银屑病学会(ASP)理事。北京医学会皮肤科分会候任主任委员,北京医师协会皮肤科分会会长。《中华皮肤科杂志》副总编、《中华变态反应和免疫学杂志》副主编、《中国临床医生杂志》副主编。
团队简介
Team Profile
带领的研究团队专注于免疫性皮肤病相关领域的临床及基础性研究,在推动免疫性皮肤病的规范化诊治和慢病管理、治疗方法优化、发病机理研究、药物临床试验、诊疗技术的普及推广等领域发挥行业引领作用。
硕士研究生 2 名,博士研究生 5 名
# | 项目名称 | 起止日期 | 金额 | 项目类型 | 本人角色 |
---|---|---|---|---|---|
1 | 脓疱型银屑病预后相关因素的病例注册登记研究 | 2022-01-01 —— 2025-12-31 | 200.0 | 主持的企业/行业委托重大项目 | 课题主持人 |
2 | 老年常见皮肤病创新疗法的临床研究 | 2022-12-01 —— 2025-12-01 | 520 | 主持在研的国家或省部级科研项目 | 课题主持人 |
3 | RNAm6A甲基化及其催化基因METTL3在寻常型银屑病中的作用及机制研究 | 2021-01-01 —— 2024-12-31 | 55 | 主持在研的国家或省部级科研项目 | 主持人 |
4 | 基于单细胞测序技术研 究制瘤素M通过JAK- STAT3通路对掌跖脓疱 病中角质形成细胞的调 控作用 | 2024-01-01 —— 2026-12-31 | 20 | 主持在研的国家或省部级科研项目 | 主持人 |
5 | 重大皮肤病精准诊疗体系的建立与转化研究 | 2022-10-01 —— 2025-09-01 | 560 | 主持的企业/行业委托重大项目 | 主持人 |
# | 论文题目 | 期刊名称 | 发表年份 | 论文署名 |
---|---|---|---|---|
1 | Interleukin (IL)-8 and IL-36 gamma but not IL-36Ra are related to acrosyringia in pustule formation associated with palmoplantar pustulosis | CLIN EXP DERMATOL | 2019-01-01 | 通讯作者 |
2 | Immune Regulation of TNFALP3 in Psoriasis through Its Association with Th1 and Th17 Cell Differentiation and p38 Activaton | Journal of Immunology Research | 2020-02-24 | 通讯作者 |
3 | Thymic Stromal Lymphopoietin Is Implicated in the Pathogenesis of Bullous Pemphigoid by Dendritic Cells | Journal of Immunology Research | 2020-09-01 | 通讯作者 |
4 | Lack of association between mutation in IL36RN and palmoplantar pustular psoriasis in Chinese patients | ANAIS BRASILEIROS DE DERMATOLOGIA | 2019-11-01 | 通讯作者 |
5 | Long-Term Follow-Up of Longevity and Diffusion Pattern of Hyaluronic Acid in Nasolabial Fold Correction through High-Frequency Ultrasound | PLASTIC AND RECONSTRUCTIVE SURGERY | 2019-08-01 | 通讯作者 |
6 | Retinol and vitamin A metabolites accumulate through RBP4 and STRA6 changes in a psoriasis murine model | Nutr Metab (Lond) | 2020-01-01 | 通讯作者 |
7 | Plasminogen activator inhibitor-1: a potential etiological role in livedoid vasculopathy | International Wound Journal | 2020-12-15 | 通讯作者 |
8 | Clinical Characteristics and Management of Patients With Clinical Amyopathic Dermatomyositis: A Retrospective Study of 64 Patients at a Tertiary Dermatology Department | FRONTIERS IN MEDICINE | 2021-12-02 | 通讯作者 |
9 | Platelet count and plateletcrit: Potential haematological biomarkers for livedoid vasculopathy? | AUSTRALASIAN JOURNAL OF DERMATOLOGY | 2022-05-30 | 通讯作者 |
10 | Efficacy of an anti-TNF-alpha agent in refractory livedoid vasculopathy: a retrospective analysis | JOURNAL OF DERMATOLOGICAL TREATMENT | 2022-03-09 | 通讯作者 |
11 | Neutrophil to lymphocyte ratio, platelet to lymphocyte ratio, and other hematological parameters in psoriasis patient | BMC immunology | 2021-09-01 | 通讯作者 |
12 | Profiling and multivariate analysis of serum cytokines in patients with generalized pustular psoriasis | European Journal of Inflammation | 2022-03-27 | 通讯作者 |
13 | tazarotene/betamethasone dipropionate cream in patients with plaque psoriasis:results of a prospective,multicenter,observational study | Dermatology | 2021-07-01 | 通讯作者 |
14 | Reduction of Methyltransferase-like 3-Mediated RNA N6-Methyladenosine Exacerbates the Development of Psoriasis Vulgaris in Imiquimod-Induced Psoriasis-like Mouse Model | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2022-10-21 | 通讯作者 |
15 | Efficacy, Safety and Pharmacokinetics of IL-17 Monoclonal Antibody Injection (AK111) in Patients with Moderate-to-Severe Plaque Psoriasis: A Randomized, Double-Blinded, Placebo-Controlled Phase Ib Multidose Escalation Clinical Study | Dermatology and Therapy | 2023-01-07 | 通讯作者 |
16 | Transcriptome-Wide m6A Methylation in Skin Lesions From Patients With Psoriasis Vulgaris | frontiers in cell and developmental biology | 2020-11-05 | 通讯作者 |
17 | Systemic monotherapy with acitretin for erythrodermic psoriasis: results of a retrospective study of 81 patients | Therapeutic Advances in Chronic Disease | 2023-06-20 | 通讯作者 |
18 | Livedoid vasculopathy and peripheral neuropathy: A retrospective cohort study of 55 Chinese patients and literature review | International Wound Journal | 2023-05-04 | 通讯作者 |
19 | Investigation of using very high‐frequency ultrasound in the differential diagnosis of early‐stage pemphigus vulgaris vs seborrheic dermatitis | SKIN RESEARCH AND TECHNOLOGY | 2020-01-13 | 通讯作者 |
20 | The efficacy and safety of 5-Aminolevulinic acid photodynamic therapy (ALA-PDT) as an adjunct therapy for symptoms in patients with dissecting cellulitis of the scalp: A retrospective study | Photodiagnosis and Photodynamic Therapy | 2021-06-01 | 通讯作者 |
21 | Inpatient Dermatology Consultations in a General Surgery Ward in a Tertiary Hospital in China: A Retrospective Study of 251 Patients | Dermatologic Therapy | 2021-04-22 | 通讯作者 |
22 | The efficacy and safety of DermalaxTM DEEP in the correction of moderate to severe nasolabial folds: a multicenter, randomized, double-blind clinical study. | JOURNAL OF DERMATOLOGICAL TREATMENT | 2021-08-01 | 通讯作者 |
23 | Characteristics and Burdens of Disease in Patients from Beijing with Generalized Pustular Psoriasis and Palmoplantar Pustulosis: Multicenter Retrospective Cohort Study Using a Regional Database. | AMERICAN JOURNAL OF CLINICAL DERMATOLOGY | 2023-06-29 | 通讯作者 |
24 | Genetics of hair graying with age | AGEING RESEARCH REVIEWS | 2023-06-03 | 通讯作者 |
25 | A Review of CRISPR-Based Advances in Dermatological Diseases | Molecular Diagnosis & Therapy | 2023-04-11 | 通讯作者 |
26 | Biologics in pediatric psoriasis | JOURNAL OF DERMATOLOGY | 2023-04-01 | 通讯作者 |
27 | An update on therapeutic options for palmoplantar pustulosis: a narrative review and expert recommendations | Expert Review of Clinical Immunology | 2023-05-04 | 通讯作者 |
28 | Circular RNA as a Potential Biomarker for Melanoma: A Systematic Review | frontiers in cell and developmental biology | 2021-04-01 | 通讯作者 |
29 | Pregnancy in adult-onset dermatomyositis/polymyositis: A systematic review | AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY | 2022-11-01 | 通讯作者 |
30 | Stigmatization in Patients With Psoriasis: A Mini Review | Frontiers in Immunology | 2021-11-15 | 通讯作者 |
31 | Association between metabolic syndrome and psoriasis: a meta-analysis of observational studies with non-psoriasis control groups. | Archives of Medical Science | 2021-11-09 | 通讯作者 |
32 | Livedoid vasculopathy and its association with genetic variants: A systematic review | International Wound Journal | 2021-10-01 | 通讯作者 |
33 | Rivaroxaban for treatment of livedoid vasculopathy: A systematic review | Dermatologic Therapy | 2021-09-01 | 通讯作者 |
34 | Efficacy and safety of intravenous immunoglobulin for treating refractory livedoid vasculopathy: a systematic review | Therapeutic Advances in Chronic Disease | 2022-05-22 | 通讯作者 |
35 | Role of interferon regulatory factor-mediated signaling in psoriasis | International Journal of Medical Sciences | 2021-10-16 | 通讯作者 |
36 | Low-Density Granulocytes in Immune-Mediated Inflammatory Diseases | JOURNAL OF IMMUNOLOGY RESEARCH | 2022-02-03 | 通讯作者 |
37 | Update on the aetiology and mechanisms of generalized pustular psoriasis | EUROPEAN JOURNAL OF DERMATOLOGY | 2021-10-01 | 通讯作者 |
38 | Role of Neutrophils in Psoriasis | JOURNAL OF IMMUNOLOGY RESEARCH | 2020-06-01 | 通讯作者 |
39 | Biologics in the treatment of pustular psoriasis | EXPERT OPINION ON DRUG SAFETY | 2020-07-01 | 通讯作者 |
40 | RNA N-6-Methyladenosine Modifications and the Immune Response | JOURNAL OF IMMUNOLOGY RESEARCH | 2020-01-01 | 通讯作者 |
41 | RNA N6-methyladenosine modification and the immune | Journal of Immunology Research | 2020-01-21 | 通讯作者 |
42 | Role of B cells in immune-mediated dermatoses | MOLECULAR IMMUNOLOGY | 2020-10-01 | 通讯作者 |
43 | Heat shock proteins and psoriasis | Eur J Dermatol | 2019-05-01 | 通讯作者 |
44 | Lack of association of the IL-1RN and IL-10 polymorphisms with risk of psoriasis: A meta-analysis | Mol Genet Genomic Med | 2019-01-20 | 通讯作者 |
45 | Exosomes in chronic inflammatory skin diseases and skin tumors | EXP DERMATOL | 2019-03-01 | 通讯作者 |
46 | Heart failure in erythrodermic psoriasis: a retrospective study of 225 patients | Frontiers in Cardiovascular Medicine | 2023-08-01 | 通讯作者 |
47 | Low-dose Interleukin-2 For Psoriasis Therapy Based on the Regulation of Th17/Treg Cell Balance in Peripheral Blood | INFLAMMATION | 2023-08-18 | 通讯作者 |
48 | Risk factors predisposing relapse of bullous pemphigoid at initial diagnosis: A retrospective cohort study of 205 patients | INTERNATIONAL IMMUNOPHARMACOLOGY | 2023-10-31 | 通讯作者 |
49 | Interleukin-17A Inhibitors in Patients with Psoriasis and Tuberculosis Infection: A 2-Year Prospective Study on Safety Without Preventive Treatment | DERMATOL THER | 2024-03-14 | 通讯作者 |
50 | Pregnancy in pemphigus vulgaris: A systematic review | AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY | 2024-01-16 | 通讯作者 |
51 | Research progress of metabolomics in psoriasis | CHINESE MEDICAL JOURNAL | 2023-08-05 | 通讯作者 |
52 | Extracellular vesicles from keratinocytes and other skin-related cells in psoriasis: A review | EXPERIMENTAL DERMATOLOGY | 2024-01-15 | 通讯作者 |
53 | Tazarotene/Betamethasone Dipropionate Cream in Patients with Plaque Psoriasis: Results of a Prospective, Multicenter, Observational Study | Dermatology | 2020-12 | 通讯作者 |
# | 获奖证书编号 | 奖项名称 | 获奖级别 | 获奖类别 | 获奖等级 | 获奖日期 | 颁奖单位 | 本单位是否为第一完成单位 | 完成单位排名 | 本人排序 | 备注 |
---|---|---|---|---|---|---|---|---|---|---|---|
1 | 2003医院-3-038-03 | 人乳头瘤病毒感染的临床和实验研究 | 省部级 | 北京市科学技术进步奖 | 三等奖 | 2004-03-01 | 北京市人民政府 | 是 | 1 | 3 | |
2 | 202202001P1501 | 免疫相关性皮肤病临床基础研究及诊疗体系建设 | 省部级以下 | 北京医学科技奖二等奖 | 特等奖 | 2023-07-26 | 北京医学会 | 是 | 1 | 1 | 2022年度奖项,2023年获批证书 |
3 | 202303267P0801 | 免疫相关性皮肤病临床基础研究及诊疗体系建设 | 省部级 | 中华医学科学技术奖 | 三等奖 | 2024-01-18 | 中华医学会 | 是 | 1 | 1 | 2023年度奖项,2024年获批证书 |
# | 成果类型 | 项目/专利/新品种名称 |
---|---|---|
1 | 作为主创人员获得授权的发明专利和新品种 | 一种便携式液氮治疗仪 |
2 | 作为主创人员获得授权的发明专利和新品种 | 红外LED照光器械 |
3 | 出版高水平专著 | 《简明皮肤病手册》 |
4 | 出版高水平专著 | 《实用皮肤病理学》 |
5 | 出版高水平专著 | 《协和皮肤临床病理学》 |
6 | 出版高水平专著 | 《临床路径释义·皮肤病及性病学分册》2022年版 |
7 | 出版高水平专著 | Dermatovenereology |
8 | 出版高水平专著 | 《皮肤病学》(第4版) |
9 | 获得省部级及以上科研奖励 | 免疫相关性皮肤病临床基础研究及诊疗体系建设 |
10 | 出版高水平专著 | 《皮肤病与性病诊疗常规》2019年版 |
11 | 出版高水平专著 | 《美容皮肤科》 |
12 | 出版高水平专著 | 《皮肤病与性病诊疗常规》2012年版 |
13 | 出版高水平专著 | 《临床路径释义·皮肤病及性病学分册》2018年版 |
14 | 出版高水平专著 | 译著《皮肤病理学精要图谱》 |
15 | 出版高水平专著 | 译著《费舍尔接触性皮炎》 |
16 | 出版高水平专著 | 译著《Hall皮肤病学:系统疾病的皮肤表现》 |